Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma
IMAGING
General Features
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kodera C et al: Clinical manifestations of placental mesenchymal dysplasia in Japan: a multicenter case series. J Obstet Gynaecol Res. 47(3):1118-25, 2021
Guenot C et al: Placental mesenchymal dysplasia: an underdiagnosed placental pathology with various clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 234:155-64, 2019
Adams HP et al: Cystic placentomegaly on a second-trimester ultrasound. JAAPA. 31(1):36-40, 2018
Jitsumori S et al: Placental mesenchymal dysplasia with severe fetal growth restriction in one placenta of a dichorionic diamniotic twin pregnancy. J Obstet Gynaecol Res. 44(5):951-4, 2018
Toru HS et al: We can diagnose it if we consider it. diagnostic pitfall for placenta: placental mesenchymal dysplasia. Turk Patoloji Derg. 34(1):100-3, 2018
Marusik C et al: Diagnosis of placental mesenchymal dysplasia with magnetic resonance imaging. Ultrasound Obstet Gynecol. 49(3):410-2, 2017
Jha P et al: Multimodality imaging of placental masses: a pictorial review. Abdom Radiol (NY). 41(12):2435-44, 2016
Ishikawa S et al: Prospective risk of stillbirth in women with placental mesenchymal dysplasia. J Obstet Gynaecol Res. 41(10):1562-8, 2015
Himoto Y et al: Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging. J Obstet Gynaecol Res. 40(7):1894-900, 2014
Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Placental mesenchymal dysplasia (PMD)
Synonyms
Pseudopartial mole
Definitions
Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma
IMAGING
General Features
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kodera C et al: Clinical manifestations of placental mesenchymal dysplasia in Japan: a multicenter case series. J Obstet Gynaecol Res. 47(3):1118-25, 2021
Guenot C et al: Placental mesenchymal dysplasia: an underdiagnosed placental pathology with various clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 234:155-64, 2019
Adams HP et al: Cystic placentomegaly on a second-trimester ultrasound. JAAPA. 31(1):36-40, 2018
Jitsumori S et al: Placental mesenchymal dysplasia with severe fetal growth restriction in one placenta of a dichorionic diamniotic twin pregnancy. J Obstet Gynaecol Res. 44(5):951-4, 2018
Toru HS et al: We can diagnose it if we consider it. diagnostic pitfall for placenta: placental mesenchymal dysplasia. Turk Patoloji Derg. 34(1):100-3, 2018
Marusik C et al: Diagnosis of placental mesenchymal dysplasia with magnetic resonance imaging. Ultrasound Obstet Gynecol. 49(3):410-2, 2017
Jha P et al: Multimodality imaging of placental masses: a pictorial review. Abdom Radiol (NY). 41(12):2435-44, 2016
Ishikawa S et al: Prospective risk of stillbirth in women with placental mesenchymal dysplasia. J Obstet Gynaecol Res. 41(10):1562-8, 2015
Himoto Y et al: Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging. J Obstet Gynaecol Res. 40(7):1894-900, 2014
Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997
STATdx includes over 200,000 searchable images, including x-ray, CT, MR, and ultrasound images. To access all images, please log in or subscribe.