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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Placental mesenchymal dysplasia (PMD)
Synonyms
- Pseudopartial mole
Definitions
- Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma
IMAGING
General Features
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kodera C et al: Clinical manifestations of placental mesenchymal dysplasia in Japan: a multicenter case series. J Obstet Gynaecol Res. 47(3):1118-25, 2021
- Guenot C et al: Placental mesenchymal dysplasia: an underdiagnosed placental pathology with various clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 234:155-64, 2019
- Adams HP et al: Cystic placentomegaly on a second-trimester ultrasound. JAAPA. 31(1):36-40, 2018
- Jitsumori S et al: Placental mesenchymal dysplasia with severe fetal growth restriction in one placenta of a dichorionic diamniotic twin pregnancy. J Obstet Gynaecol Res. 44(5):951-4, 2018
- Toru HS et al: We can diagnose it if we consider it. diagnostic pitfall for placenta: placental mesenchymal dysplasia. Turk Patoloji Derg. 34(1):100-3, 2018
- Marusik C et al: Diagnosis of placental mesenchymal dysplasia with magnetic resonance imaging. Ultrasound Obstet Gynecol. 49(3):410-2, 2017
- Jha P et al: Multimodality imaging of placental masses: a pictorial review. Abdom Radiol (NY). 41(12):2435-44, 2016
- Ishikawa S et al: Prospective risk of stillbirth in women with placental mesenchymal dysplasia. J Obstet Gynaecol Res. 41(10):1562-8, 2015
- Himoto Y et al: Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging. J Obstet Gynaecol Res. 40(7):1894-900, 2014
- Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
- Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
- Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
- Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
- Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
- Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
- Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Placental mesenchymal dysplasia (PMD)
Synonyms
- Pseudopartial mole
Definitions
- Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma
IMAGING
General Features
Ultrasonographic Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kodera C et al: Clinical manifestations of placental mesenchymal dysplasia in Japan: a multicenter case series. J Obstet Gynaecol Res. 47(3):1118-25, 2021
- Guenot C et al: Placental mesenchymal dysplasia: an underdiagnosed placental pathology with various clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 234:155-64, 2019
- Adams HP et al: Cystic placentomegaly on a second-trimester ultrasound. JAAPA. 31(1):36-40, 2018
- Jitsumori S et al: Placental mesenchymal dysplasia with severe fetal growth restriction in one placenta of a dichorionic diamniotic twin pregnancy. J Obstet Gynaecol Res. 44(5):951-4, 2018
- Toru HS et al: We can diagnose it if we consider it. diagnostic pitfall for placenta: placental mesenchymal dysplasia. Turk Patoloji Derg. 34(1):100-3, 2018
- Marusik C et al: Diagnosis of placental mesenchymal dysplasia with magnetic resonance imaging. Ultrasound Obstet Gynecol. 49(3):410-2, 2017
- Jha P et al: Multimodality imaging of placental masses: a pictorial review. Abdom Radiol (NY). 41(12):2435-44, 2016
- Ishikawa S et al: Prospective risk of stillbirth in women with placental mesenchymal dysplasia. J Obstet Gynaecol Res. 41(10):1562-8, 2015
- Himoto Y et al: Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging. J Obstet Gynaecol Res. 40(7):1894-900, 2014
- Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
- Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
- Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
- Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
- Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
- Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
- Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997
