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Placental Mesenchymal Dysplasia
Anne M. Kennedy, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Placental mesenchymal dysplasia (PMD)
              • Synonyms

                • Pseudopartial mole
              • Definitions

                • Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
                                    2. Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
                                    3. Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
                                    4. Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
                                    5. Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
                                    6. Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
                                    7. Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Placental mesenchymal dysplasia (PMD)
                                                • Synonyms

                                                  • Pseudopartial mole
                                                • Definitions

                                                  • Abnormal placental development characterized by placentomegaly, stem-villous hydropic cyst formation, and abnormal villous stroma

                                                IMAGING

                                                • General Features

                                                  • Ultrasonographic Findings

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Gross Pathologic & Surgical Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Nayeri UA et al: Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 41(4):366-74, 2013
                                                                      2. Ruhland B et al: Prenatal imaging and postnatal pathologic work-up in a case of fetal hepatic hamartoma and placental mesenchymal dysplasia. Ultrasound Obstet Gynecol. 38(3):360-2, 2011
                                                                      3. Parveen Z et al: Placental mesenchymal dysplasia. Arch Pathol Lab Med. 131(1):131-7, 2007
                                                                      4. Robertson M et al: Mesenchymal dysplasia in a monochorionic diamniotic twin pregnancy with review of the differential diagnosis of cystic changes in the placenta. J Ultrasound Med. 26(5):689-93, 2007
                                                                      5. Pham T et al: Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol. 126(1):67-78, 2006
                                                                      6. Ohyama M et al: Mesenchymal dysplasia of the placenta. Pathol Int. 50(9):759-64, 2000
                                                                      7. Jauniaux E et al: Perinatal features associated with placental mesenchymal dysplasia. Placenta. 18(8):701-6, 1997