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Pleural Fibrosis and Fibrothorax
Allen Heeger, DO
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Pleural fibrosis
              • Fibrothorax
            • Definitions

              • Abnormal pleural thickening and calcification with resultant volume loss

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Natural History & Prognosis

                            • Treatment

                              DIAGNOSTIC CHECKLIST

                              • Consider

                                Selected References

                                1. Adrianza AM et al: Tyrosine kinase inhibitor-associated fibrothorax. Am J Respir Crit Care Med. 199(11):1432, 2019
                                2. Hallifax RJ et al: State-of-the-art: radiological investigation of pleural disease. Respir Med. 124:88-99, 2017
                                3. Batra H et al: Pleural mesothelial cells in pleural and lung diseases. J Thorac Dis. 7(6):964-80, 2015
                                4. Downer NJ et al: Investigating pleural thickening. BMJ. 346:e8376, 2013
                                5. Donath J et al: Restrictive chest wall disorders. Semin Respir Crit Care Med. 30(3):275-92, 2009
                                6. Jantz MA et al: Pleural fibrosis. Clin Chest Med. 27(2):181-91, 2006
                                7. Huggins JT et al: Causes and management of pleural fibrosis. Respirology. 9(4):441-7, 2004
                                8. Kim HY et al: Thoracic sequelae and complications of tuberculosis. Radiographics. 21(4):839-58; discussion 859-60, 2001
                                9. Ghoshal AG et al: Fibrothorax--problem, profile and prevention. J Indian Med Assoc. 95(12):610-2, 1997
                                10. Brown K et al: Intrathoracic calcifications: radiographic features and differential diagnoses. Radiographics. 14(6):1247-61, 1994
                                11. Deslauriers J et al: Fibrothorax and decortication. Ann Thorac Surg. 58(1):267-8, 1994
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Pathology

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Synonyms

                                            • Pleural fibrosis
                                            • Fibrothorax
                                          • Definitions

                                            • Abnormal pleural thickening and calcification with resultant volume loss

                                          IMAGING

                                          • General Features

                                            • Radiographic Findings

                                              • CT Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Natural History & Prognosis

                                                          • Treatment

                                                            DIAGNOSTIC CHECKLIST

                                                            • Consider

                                                              Selected References

                                                              1. Adrianza AM et al: Tyrosine kinase inhibitor-associated fibrothorax. Am J Respir Crit Care Med. 199(11):1432, 2019
                                                              2. Hallifax RJ et al: State-of-the-art: radiological investigation of pleural disease. Respir Med. 124:88-99, 2017
                                                              3. Batra H et al: Pleural mesothelial cells in pleural and lung diseases. J Thorac Dis. 7(6):964-80, 2015
                                                              4. Downer NJ et al: Investigating pleural thickening. BMJ. 346:e8376, 2013
                                                              5. Donath J et al: Restrictive chest wall disorders. Semin Respir Crit Care Med. 30(3):275-92, 2009
                                                              6. Jantz MA et al: Pleural fibrosis. Clin Chest Med. 27(2):181-91, 2006
                                                              7. Huggins JT et al: Causes and management of pleural fibrosis. Respirology. 9(4):441-7, 2004
                                                              8. Kim HY et al: Thoracic sequelae and complications of tuberculosis. Radiographics. 21(4):839-58; discussion 859-60, 2001
                                                              9. Ghoshal AG et al: Fibrothorax--problem, profile and prevention. J Indian Med Assoc. 95(12):610-2, 1997
                                                              10. Brown K et al: Intrathoracic calcifications: radiographic features and differential diagnoses. Radiographics. 14(6):1247-61, 1994
                                                              11. Deslauriers J et al: Fibrothorax and decortication. Ann Thorac Surg. 58(1):267-8, 1994