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Pleural Plaques
Allen Heeger, DO
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Fibrohyaline acellular lesion predominantly involving parietal pleura
                • Often along diaphragm and rib undersurfaces

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. Brims FJH et al: Pleural plaques and the risk of lung cancer in asbestos-exposed subjects. Am J Respir Crit Care Med. 201(1):57-62, 2020
                                              2. Batra H et al: Pleural mesothelial cells in pleural and lung diseases. J Thorac Dis. 7(6):964-80, 2015
                                              3. Norbet C et al: Asbestos-related lung disease: a pictorial review. Curr Probl Diagn Radiol. 44(4):371-82, 2015
                                              4. Cox CW et al: State of the art: Imaging of occupational lung disease. Radiology. 270(3):681-96, 2014
                                              5. Pairon JC et al: Asbestos exposure, pleural plaques, and the risk of death from lung cancer. Am J Respir Crit Care Med. 190(12):1413-20, 2014
                                              6. Jamrozik E et al: Clinical review: asbestos-related disease. Intern Med J. 2011 Feb 10. doi: 10.1111/j.1445-5994. 2011. ;41(5):372-80, 0245
                                              7. Kukkonen MK et al: Genetic susceptibility to asbestos-related fibrotic pleuropulmonary changes. Eur Respir J. 38(3):672-8, 2011
                                              8. Larson TC et al: Workers with Libby amphibole exposure: retrospective identification and progression of radiographic changes. Radiology. 255(3):924-33, 2010
                                              9. Nguyen NC et al: F-18 FDG PET/CT characterization of talc pleurodesis-induced pleural changes over time: a retrospective study. Clin Nucl Med. 34(12):886-90, 2009
                                              10. Paris C et al: Pleural plaques and asbestosis: dose- and time-response relationships based on HRCT data. Eur Respir J. 34(1):72-9, 2009
                                              11. Peretz A et al: Pleural plaques related to "take-home" exposure to asbestos: An international case series. Int J Gen Med. 1:15-20, 2009
                                              12. Greillier L et al: Mesothelioma and asbestos-related pleural diseases. Respiration. 76(1):1-15, 2008
                                              13. Hansell DM et al: Fleischner Society: glossary of terms for thoracic imaging. Radiology. 246(3):697-722, 2008
                                              14. Burkill GJ et al: Re: CT appearances of talc pleurodesis. Clin Radiol. 62(9):914-5, 2007
                                              15. Yamamuro M et al: Morphologic and functional imaging of malignant pleural mesothelioma. Eur J Radiol. 64(3):356-66, 2007
                                              16. Clarke CC et al: Pleural plaques: a review of diagnostic issues and possible nonasbestos factors. Arch Environ Occup Health. 61(4):183-92, 2006
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Fibrohyaline acellular lesion predominantly involving parietal pleura
                                                            • Often along diaphragm and rib undersurfaces

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Ultrasonographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. Brims FJH et al: Pleural plaques and the risk of lung cancer in asbestos-exposed subjects. Am J Respir Crit Care Med. 201(1):57-62, 2020
                                                                                          2. Batra H et al: Pleural mesothelial cells in pleural and lung diseases. J Thorac Dis. 7(6):964-80, 2015
                                                                                          3. Norbet C et al: Asbestos-related lung disease: a pictorial review. Curr Probl Diagn Radiol. 44(4):371-82, 2015
                                                                                          4. Cox CW et al: State of the art: Imaging of occupational lung disease. Radiology. 270(3):681-96, 2014
                                                                                          5. Pairon JC et al: Asbestos exposure, pleural plaques, and the risk of death from lung cancer. Am J Respir Crit Care Med. 190(12):1413-20, 2014
                                                                                          6. Jamrozik E et al: Clinical review: asbestos-related disease. Intern Med J. 2011 Feb 10. doi: 10.1111/j.1445-5994. 2011. ;41(5):372-80, 0245
                                                                                          7. Kukkonen MK et al: Genetic susceptibility to asbestos-related fibrotic pleuropulmonary changes. Eur Respir J. 38(3):672-8, 2011
                                                                                          8. Larson TC et al: Workers with Libby amphibole exposure: retrospective identification and progression of radiographic changes. Radiology. 255(3):924-33, 2010
                                                                                          9. Nguyen NC et al: F-18 FDG PET/CT characterization of talc pleurodesis-induced pleural changes over time: a retrospective study. Clin Nucl Med. 34(12):886-90, 2009
                                                                                          10. Paris C et al: Pleural plaques and asbestosis: dose- and time-response relationships based on HRCT data. Eur Respir J. 34(1):72-9, 2009
                                                                                          11. Peretz A et al: Pleural plaques related to "take-home" exposure to asbestos: An international case series. Int J Gen Med. 1:15-20, 2009
                                                                                          12. Greillier L et al: Mesothelioma and asbestos-related pleural diseases. Respiration. 76(1):1-15, 2008
                                                                                          13. Hansell DM et al: Fleischner Society: glossary of terms for thoracic imaging. Radiology. 246(3):697-722, 2008
                                                                                          14. Burkill GJ et al: Re: CT appearances of talc pleurodesis. Clin Radiol. 62(9):914-5, 2007
                                                                                          15. Yamamuro M et al: Morphologic and functional imaging of malignant pleural mesothelioma. Eur J Radiol. 64(3):356-66, 2007
                                                                                          16. Clarke CC et al: Pleural plaques: a review of diagnostic issues and possible nonasbestos factors. Arch Environ Occup Health. 61(4):183-92, 2006