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*Pneumocystis jirovecii* Pneumonia
Sherief H. Garrana, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Pneumocystis pneumonia (PCP)
              • Pneumocystis jirovecii pneumonia (PJP)
            • Definitions

              • Opportunistic fungal infection that often affects individuals with T-cell immunodeficiency
                • P. jirovecii

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Du CJ et al: Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients. Infect Dis Poverty. 9(1):149, 2020
                                        2. Hsu JM et al: Radiographic features in investigated for Pneumocystis jirovecii pneumonia: a nested case-control study. BMC Infect Dis. 20(1):492, 2020
                                        3. Cereser L et al: Pneumocystis jirovecii pneumonia at chest high-resolution computed tomography (HRCT) in non-HIV immunocompromised patients: spectrum of findings and mimickers. Eur J Radiol. 116:116-27, 2019
                                        4. Kloth C et al: Potential role of CT-textural features for differentiation between viral interstitial pneumonias, pneumocystis jirovecii pneumonia and diffuse alveolar hemorrhage in early stages of disease: a proof of principle. BMC Med Imaging. 19(1):39, 2019
                                        5. Schmidt JJ et al: Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years. Crit Care. 22(1):307, 2018
                                        6. Liu Y et al: Risk factors for mortality from pneumocystis carinii pneumonia (PCP) in non-HIV patients: a meta-analysis. Oncotarget. 8(35):59729-39, 2017
                                        7. Kanne JP et al: Pneumocystis jiroveci pneumonia: high-resolution CT findings in patients with and without HIV infection. AJR Am J Roentgenol. 198(6):W555-61, 2012
                                        8. Hardak E et al: Radiological features of Pneumocystis jirovecii pneumonia in immunocompromised patients with and without AIDS. Lung. 188(2):159-63, 2010
                                        9. Tasaka S et al: Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study. Intern Med. 49(4):273-81, 2010
                                        10. D'Avignon LC et al: Pneumocystis pneumonia. Semin Respir Crit Care Med. 29(2):132-40, 2008
                                        11. Kuhlman JE: Pneumocystic infections: the radiologist's perspective. Radiology. 198(3):623-35, 1996
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Pneumocystis pneumonia (PCP)
                                                    • Pneumocystis jirovecii pneumonia (PJP)
                                                  • Definitions

                                                    • Opportunistic fungal infection that often affects individuals with T-cell immunodeficiency
                                                      • P. jirovecii

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Du CJ et al: Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients. Infect Dis Poverty. 9(1):149, 2020
                                                                              2. Hsu JM et al: Radiographic features in investigated for Pneumocystis jirovecii pneumonia: a nested case-control study. BMC Infect Dis. 20(1):492, 2020
                                                                              3. Cereser L et al: Pneumocystis jirovecii pneumonia at chest high-resolution computed tomography (HRCT) in non-HIV immunocompromised patients: spectrum of findings and mimickers. Eur J Radiol. 116:116-27, 2019
                                                                              4. Kloth C et al: Potential role of CT-textural features for differentiation between viral interstitial pneumonias, pneumocystis jirovecii pneumonia and diffuse alveolar hemorrhage in early stages of disease: a proof of principle. BMC Med Imaging. 19(1):39, 2019
                                                                              5. Schmidt JJ et al: Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years. Crit Care. 22(1):307, 2018
                                                                              6. Liu Y et al: Risk factors for mortality from pneumocystis carinii pneumonia (PCP) in non-HIV patients: a meta-analysis. Oncotarget. 8(35):59729-39, 2017
                                                                              7. Kanne JP et al: Pneumocystis jiroveci pneumonia: high-resolution CT findings in patients with and without HIV infection. AJR Am J Roentgenol. 198(6):W555-61, 2012
                                                                              8. Hardak E et al: Radiological features of Pneumocystis jirovecii pneumonia in immunocompromised patients with and without AIDS. Lung. 188(2):159-63, 2010
                                                                              9. Tasaka S et al: Comparison of clinical and radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: a multicenter study. Intern Med. 49(4):273-81, 2010
                                                                              10. D'Avignon LC et al: Pneumocystis pneumonia. Semin Respir Crit Care Med. 29(2):132-40, 2008
                                                                              11. Kuhlman JE: Pneumocystic infections: the radiologist's perspective. Radiology. 198(3):623-35, 1996