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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Polymyositis/dermatomyositis (P/D)
Synonyms
- P/D interstitial lung disease (ILD)
- Idiopathic inflammatory myopathy ILD
Definitions
- Autoimmune myopathy
- Manifests with inflammation and weakness
- Dermatomyositis exhibits variety of cutaneous manifestations
- Polymyositis involves proximal muscles over weeks or months
- May be complicated by connective tissue disease-associated ILD (CTD-ILD), aspiration bronchiolitis, &/or hypoventilation from affected respiratory muscles
- CTD-ILD: Diffuse interstitial pneumonia secondary to P/D
- Aspiration bronchiolitis: Typically diffuse
- Autoimmune myopathy
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Elicker BM et al: Imaging of the thoracic manifestations of connective tissue disease. Clin Chest Med. 40(3):655-66, 2019
- Kusmirek JE et al: Thoracic manifestations of connective tissue diseases. Semin Ultrasound CT MR. 40(3):239-54, 2019
- Ahuja J et al: Imaging of pulmonary manifestations of connective tissue diseases. Radiol Clin North Am. 54(6):1015-31, 2016
- Wang H et al: Pulmonary hypertension in polymyositis. Clin Rheumatol. 34(12):2105-12, 2015
- Tanizawa K et al: The prognostic value of HRCT in myositis-associated interstitial lung disease. Respir Med. 107(5):745-52, 2013
- Hervier B et al: Clinical manifestations of anti-synthetase syndrome positive for anti-alanyl-tRNA synthetase (anti-PL12) antibodies: a retrospective study of 17 cases. Rheumatology (Oxford). 49(5):972-6, 2010
- Chen IJ et al: Interstitial lung disease in polymyositis and dermatomyositis. Clin Rheumatol. 28(6):639-46, 2009
- Kang EH et al: Interstitial lung disease in patients with polymyositis, dermatomyositis and amyopathic dermatomyositis. Rheumatology (Oxford). 44(10):1282-6, 2005
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References
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Polymyositis/dermatomyositis (P/D)
Synonyms
- P/D interstitial lung disease (ILD)
- Idiopathic inflammatory myopathy ILD
Definitions
- Autoimmune myopathy
- Manifests with inflammation and weakness
- Dermatomyositis exhibits variety of cutaneous manifestations
- Polymyositis involves proximal muscles over weeks or months
- May be complicated by connective tissue disease-associated ILD (CTD-ILD), aspiration bronchiolitis, &/or hypoventilation from affected respiratory muscles
- CTD-ILD: Diffuse interstitial pneumonia secondary to P/D
- Aspiration bronchiolitis: Typically diffuse
- Autoimmune myopathy
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Elicker BM et al: Imaging of the thoracic manifestations of connective tissue disease. Clin Chest Med. 40(3):655-66, 2019
- Kusmirek JE et al: Thoracic manifestations of connective tissue diseases. Semin Ultrasound CT MR. 40(3):239-54, 2019
- Ahuja J et al: Imaging of pulmonary manifestations of connective tissue diseases. Radiol Clin North Am. 54(6):1015-31, 2016
- Wang H et al: Pulmonary hypertension in polymyositis. Clin Rheumatol. 34(12):2105-12, 2015
- Tanizawa K et al: The prognostic value of HRCT in myositis-associated interstitial lung disease. Respir Med. 107(5):745-52, 2013
- Hervier B et al: Clinical manifestations of anti-synthetase syndrome positive for anti-alanyl-tRNA synthetase (anti-PL12) antibodies: a retrospective study of 17 cases. Rheumatology (Oxford). 49(5):972-6, 2010
- Chen IJ et al: Interstitial lung disease in polymyositis and dermatomyositis. Clin Rheumatol. 28(6):639-46, 2009
- Kang EH et al: Interstitial lung disease in patients with polymyositis, dermatomyositis and amyopathic dermatomyositis. Rheumatology (Oxford). 44(10):1282-6, 2005
