Dong J et al: Differentiation between ependymoma and medulloblastoma in children with radiomics approach. Acad Radiol. 28(3):318-27, 2020
Quon JL et al: Deep learning for pediatric posterior fossa tumor detection and classification: a multi-institutional study. AJNR Am J Neuroradiol. 41(9):1718-25, 2020
Takeishi Y et al: Advantage of high b value diffusion-weighted imaging for differentiation of common pediatric brain tumors in posterior fossa. Eur J Radiol. 128:108983, 2020
Zhou H et al: Automatic machine learning to differentiate pediatric posterior fossa tumors on routine MR imaging. AJNR Am J Neuroradiol. 41(7):1279-85, 2020
Jünger ST et al: Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort. Acta Neuropathol Commun. 7(1):181, 2019
Ma SC et al: Clinical characteristics and prognostic factors of treatment in pediatric posterior cranial fossa ependymoma. Pediatr Neurosurg. 54(2):98-107, 2019
Zapotocky M et al: Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost. Cancer.125(11):1867-76, 2019
Ramaswamy V et al: Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis. J Clin Oncol. 34(21):2468-77, 2016
Sabin ND et al: Quantitative imaging analysis of posterior fossa ependymoma location in children. Childs Nerv Syst. 32(8):1441-7, 2016
Archer TC et al: Defining the molecular landscape of ependymomas. Cancer Cell. 27(5):613-5, 2015
Huse JT et al: The emerging molecular foundations of pediatric brain tumors. J Child Neurol. 30(13):1838-50, 2015
Mohankumar KM et al: An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes. Nat Genet. 47(8):878-87, 2015
Nowak J et al: Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified. Neuro Oncol. 17(8):1157-65, 2015
Pajtler KW et al: Molecular classification of ependymal tumors across all CNS compartments, Histopathological Grades, and Age Groups. Cancer Cell. 27(5):728-43, 2015
Thompson YY et al: Posterior fossa ependymoma: current insights. Childs Nerv Syst. 31(10):1699-706, 2015
Mack SC et al: Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506(7489):445-50, 2014
Nobusawa S et al: Molecular genetics of ependymomas and pediatric diffuse gliomas: a short review. Brain Tumor Pathol. 31(4):229-33, 2014
Merchant TE et al: Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. Lancet Oncol. 10(3):258-66, 2009
Yuh EL et al: Imaging of ependymomas: MRI and CT. Childs Nerv Syst. 25(10):1203-13, 2009
Schneider JF et al: Multiparametric differentiation of posterior fossa tumors in children using diffusion-weighted imaging and short echo-time 1H-MR spectroscopy. J Magn Reson Imaging. 26(6):1390-8, 2007
Fouladi M et al: Clear cell ependymoma: a clinicopathologic and radiographic analysis of 10 patients. Cancer. 98(10):2232-44, 2003
Good CD et al: Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? J Neurosurg. 94(1):27-32, 2001
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Posterior fossa ependymoma (PF-EPN)
Slow-growing tumor of ependymal cells
IMAGING
General Features
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Dong J et al: Differentiation between ependymoma and medulloblastoma in children with radiomics approach. Acad Radiol. 28(3):318-27, 2020
Quon JL et al: Deep learning for pediatric posterior fossa tumor detection and classification: a multi-institutional study. AJNR Am J Neuroradiol. 41(9):1718-25, 2020
Takeishi Y et al: Advantage of high b value diffusion-weighted imaging for differentiation of common pediatric brain tumors in posterior fossa. Eur J Radiol. 128:108983, 2020
Zhou H et al: Automatic machine learning to differentiate pediatric posterior fossa tumors on routine MR imaging. AJNR Am J Neuroradiol. 41(7):1279-85, 2020
Jünger ST et al: Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort. Acta Neuropathol Commun. 7(1):181, 2019
Ma SC et al: Clinical characteristics and prognostic factors of treatment in pediatric posterior cranial fossa ependymoma. Pediatr Neurosurg. 54(2):98-107, 2019
Zapotocky M et al: Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost. Cancer.125(11):1867-76, 2019
Ramaswamy V et al: Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis. J Clin Oncol. 34(21):2468-77, 2016
Sabin ND et al: Quantitative imaging analysis of posterior fossa ependymoma location in children. Childs Nerv Syst. 32(8):1441-7, 2016
Archer TC et al: Defining the molecular landscape of ependymomas. Cancer Cell. 27(5):613-5, 2015
Huse JT et al: The emerging molecular foundations of pediatric brain tumors. J Child Neurol. 30(13):1838-50, 2015
Mohankumar KM et al: An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes. Nat Genet. 47(8):878-87, 2015
Nowak J et al: Systematic comparison of MRI findings in pediatric ependymoblastoma with ependymoma and CNS primitive neuroectodermal tumor not otherwise specified. Neuro Oncol. 17(8):1157-65, 2015
Pajtler KW et al: Molecular classification of ependymal tumors across all CNS compartments, Histopathological Grades, and Age Groups. Cancer Cell. 27(5):728-43, 2015
Thompson YY et al: Posterior fossa ependymoma: current insights. Childs Nerv Syst. 31(10):1699-706, 2015
Mack SC et al: Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506(7489):445-50, 2014
Nobusawa S et al: Molecular genetics of ependymomas and pediatric diffuse gliomas: a short review. Brain Tumor Pathol. 31(4):229-33, 2014
Merchant TE et al: Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. Lancet Oncol. 10(3):258-66, 2009
Yuh EL et al: Imaging of ependymomas: MRI and CT. Childs Nerv Syst. 25(10):1203-13, 2009
Schneider JF et al: Multiparametric differentiation of posterior fossa tumors in children using diffusion-weighted imaging and short echo-time 1H-MR spectroscopy. J Magn Reson Imaging. 26(6):1390-8, 2007
Fouladi M et al: Clear cell ependymoma: a clinicopathologic and radiographic analysis of 10 patients. Cancer. 98(10):2232-44, 2003
Good CD et al: Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? J Neurosurg. 94(1):27-32, 2001
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