link
Bookmarks
 (0)
Spine
Diagnosis
Spine Postprocedural Imaging
Post Radiation and Chemotherapy Complications
Postirradiation Vertebral Marrow
Postirradiation Vertebral Marrow
Kevin R. Moore, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
9
2
1

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Transformation of cellular vertebral marrow into fatty marrow following therapeutic irradiation

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Other Modality Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Caranci F et al: Magnetic resonance imaging correlates of benign and malignant alterations of the spinal bone marrow. Acta Biomed. 89(1-S):18-33, 2018
                                              2. Meixel AJ et al: From radiation osteitis to osteoradionecrosis: incidence and MR morphology of radiation-induced sacral pathologies following pelvic radiotherapy. Eur Radiol. 28(8):3550-9, 2018
                                              3. Yoo HJ et al: Measurement of fat content in vertebral marrow using a modified dixon sequence to differentiate benign from malignant processes. J Magn Reson Imaging. 45(5):1534-44, 2017
                                              4. Escalas C et al: [Long-term effects of radiation on the spine - results of a cohort of symptomatic survivors of childhood and review of the literature.] Bull Cancer. 102(7-8):684-90, 2015
                                              5. Carmona R et al: Fat composition changes in bone marrow during chemotherapy and radiation therapy. Int J Radiat Oncol Biol Phys. 90(1):155-63, 2014
                                              6. Bolan PJ et al: Water-fat MRI for assessing changes in bone marrow composition due to radiation and chemotherapy in gynecologic cancer patients. J Magn Reson Imaging. 38(6):1578-84, 2013
                                              7. Hwang S et al: Magnetic resonance imaging of bone marrow in oncology, Part 2. Skeletal Radiol. 36(11):1017-27, 2007
                                              8. Tall MA et al: MR imaging of the spinal bone marrow. Magn Reson Imaging Clin N Am. 15(2):175-98, vi, 2007
                                              9. Foster K et al: MRI of the marrow in the paediatric skeleton. Clin Radiol. 59(8):651-73, 2004
                                              10. Shih WJ et al: Tc-99m depreotide SPECT demonstrates photon-deficiency in the thoracic vertebrae after adjunct radiation therapy of lung cancer: correlation with MRI and bone scintigraphy. Ann Nucl Med. 17(3):245-8, 2003
                                              11. Otake S et al: Radiation-induced changes in MR signal intensity and contrast enhancement of lumbosacral vertebrae: do changes occur only inside the radiation therapy field? Radiology. 222(1):179-83, 2002
                                              12. Onu M et al: Early MR changes in vertebral bone marrow for patients following radiotherapy. Eur Radiol. 11(8):1463-9, 2001
                                              13. Meyer MA et al: Reduced F-18 fluorodeoxyglucose uptake within marrow after external beam radiation. Clin Nucl Med. 25(4):279-80, 2000
                                              14. Blomlie V et al: Female pelvic bone marrow: serial MR imaging before, during, and after radiation therapy. Radiology. 194(2):537-43, 1995
                                              15. Cavenagh EC et al: Hematopoietic marrow regeneration in pediatric patients undergoing spinal irradiation: MR depiction. AJNR Am J Neuroradiol. 16(3):461-7, 1995
                                              16. Steiner RM et al: Magnetic resonance imaging of diffuse bone marrow disease. Radiol Clin North Am. 31(2):383-409, 1993
                                              17. Yankelevitz DF et al: Effect of radiation therapy on thoracic and lumbar bone marrow: evaluation with MR imaging. AJR Am J Roentgenol. 157(1):87-92, 1991
                                              18. Stevens SK et al: Early and late bone-marrow changes after irradiation: MR evaluation. AJR Am J Roentgenol. 154(4):745-50, 1990
                                              19. Casamassima F et al: Hematopoietic bone marrow recovery after radiation therapy: MRI evaluation. Blood. 73(6):1677-81, 1989
                                              20. Naul LG et al: Avascular necrosis of the vertebral body: MR imaging. Radiology. 172(1):219-22, 1989
                                              21. Rosenthal DI et al: Fatty replacement of spinal bone marrow due to radiation: demonstration by dual energy quantitative CT and MR imaging. J Comput Assist Tomogr. 13(3):463-5, 1989
                                              22. Shih WJ et al: Thoracic vertebral photopenia may predict fatty changes of the corresponding bone marrow following irradiation. Radiat Med. 7(1):32-5, 1989
                                              23. Ramsey RG et al: MR imaging of the spine after radiation therapy: easily recognizable effects. AJR Am J Roentgenol. 144(6):1131-5, 1985
                                              24. Maldague BE et al: The intravertebral vacuum cleft: a sign of ischemic vertebral collapse. Radiology. 129(1):23-9, 1978
                                              Related Anatomy
                                              Loading...
                                              Related Differential Diagnoses
                                              Loading...
                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Definitions

                                                            • Transformation of cellular vertebral marrow into fatty marrow following therapeutic irradiation

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Other Modality Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Caranci F et al: Magnetic resonance imaging correlates of benign and malignant alterations of the spinal bone marrow. Acta Biomed. 89(1-S):18-33, 2018
                                                                                          2. Meixel AJ et al: From radiation osteitis to osteoradionecrosis: incidence and MR morphology of radiation-induced sacral pathologies following pelvic radiotherapy. Eur Radiol. 28(8):3550-9, 2018
                                                                                          3. Yoo HJ et al: Measurement of fat content in vertebral marrow using a modified dixon sequence to differentiate benign from malignant processes. J Magn Reson Imaging. 45(5):1534-44, 2017
                                                                                          4. Escalas C et al: [Long-term effects of radiation on the spine - results of a cohort of symptomatic survivors of childhood and review of the literature.] Bull Cancer. 102(7-8):684-90, 2015
                                                                                          5. Carmona R et al: Fat composition changes in bone marrow during chemotherapy and radiation therapy. Int J Radiat Oncol Biol Phys. 90(1):155-63, 2014
                                                                                          6. Bolan PJ et al: Water-fat MRI for assessing changes in bone marrow composition due to radiation and chemotherapy in gynecologic cancer patients. J Magn Reson Imaging. 38(6):1578-84, 2013
                                                                                          7. Hwang S et al: Magnetic resonance imaging of bone marrow in oncology, Part 2. Skeletal Radiol. 36(11):1017-27, 2007
                                                                                          8. Tall MA et al: MR imaging of the spinal bone marrow. Magn Reson Imaging Clin N Am. 15(2):175-98, vi, 2007
                                                                                          9. Foster K et al: MRI of the marrow in the paediatric skeleton. Clin Radiol. 59(8):651-73, 2004
                                                                                          10. Shih WJ et al: Tc-99m depreotide SPECT demonstrates photon-deficiency in the thoracic vertebrae after adjunct radiation therapy of lung cancer: correlation with MRI and bone scintigraphy. Ann Nucl Med. 17(3):245-8, 2003
                                                                                          11. Otake S et al: Radiation-induced changes in MR signal intensity and contrast enhancement of lumbosacral vertebrae: do changes occur only inside the radiation therapy field? Radiology. 222(1):179-83, 2002
                                                                                          12. Onu M et al: Early MR changes in vertebral bone marrow for patients following radiotherapy. Eur Radiol. 11(8):1463-9, 2001
                                                                                          13. Meyer MA et al: Reduced F-18 fluorodeoxyglucose uptake within marrow after external beam radiation. Clin Nucl Med. 25(4):279-80, 2000
                                                                                          14. Blomlie V et al: Female pelvic bone marrow: serial MR imaging before, during, and after radiation therapy. Radiology. 194(2):537-43, 1995
                                                                                          15. Cavenagh EC et al: Hematopoietic marrow regeneration in pediatric patients undergoing spinal irradiation: MR depiction. AJNR Am J Neuroradiol. 16(3):461-7, 1995
                                                                                          16. Steiner RM et al: Magnetic resonance imaging of diffuse bone marrow disease. Radiol Clin North Am. 31(2):383-409, 1993
                                                                                          17. Yankelevitz DF et al: Effect of radiation therapy on thoracic and lumbar bone marrow: evaluation with MR imaging. AJR Am J Roentgenol. 157(1):87-92, 1991
                                                                                          18. Stevens SK et al: Early and late bone-marrow changes after irradiation: MR evaluation. AJR Am J Roentgenol. 154(4):745-50, 1990
                                                                                          19. Casamassima F et al: Hematopoietic bone marrow recovery after radiation therapy: MRI evaluation. Blood. 73(6):1677-81, 1989
                                                                                          20. Naul LG et al: Avascular necrosis of the vertebral body: MR imaging. Radiology. 172(1):219-22, 1989
                                                                                          21. Rosenthal DI et al: Fatty replacement of spinal bone marrow due to radiation: demonstration by dual energy quantitative CT and MR imaging. J Comput Assist Tomogr. 13(3):463-5, 1989
                                                                                          22. Shih WJ et al: Thoracic vertebral photopenia may predict fatty changes of the corresponding bone marrow following irradiation. Radiat Med. 7(1):32-5, 1989
                                                                                          23. Ramsey RG et al: MR imaging of the spine after radiation therapy: easily recognizable effects. AJR Am J Roentgenol. 144(6):1131-5, 1985
                                                                                          24. Maldague BE et al: The intravertebral vacuum cleft: a sign of ischemic vertebral collapse. Radiology. 129(1):23-9, 1978
                                                                                          Contact UsStoreTerms and ConditionsRegistered User AgreementPrivacy PolicyHelp