Heterogeneous group of lymphoproliferative diseases that occur in posttransplant setting (either solid organ or stem cell transplants), ranging from abnormal lymphoid hyperplasias to frank malignancies
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Fluoroscopic Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kim DH et al: Diagnostic performances of F-18 FDG PET or PET/CT for detection of post-transplant lymphoproliferative disorder: a systematic review and meta-analysis. Nucl Med Commun. 41(6):533-9, 2020
Montes de Jesus FM et al: Diagnostic performance of FDG-PET/CT of post-transplant lymphoproliferative disorder and factors affecting diagnostic yield. Eur J Nucl Med Mol Imaging. 47(3):529-36, 2020
Xu YF et al: Roles of F-18-fluoro-2-deoxy-glucose PET/computed tomography scans in the management of post-transplant lymphoproliferative disease in Pediatric Patient. PET Clin. 15(3):309-19, 2020
Katabathina V et al: Complications of immunosuppressive therapy in solid organ transplantation. Radiol Clin North Am. 54(2):303-19, 2016
Takehana CS et al: (18)F-FDG PET/CT in the management of patients with post-transplant lymphoproliferative disorder. Nucl Med Commun. 35(3):276-81, 2014
Blaes AH et al: Positron emission tomography scanning in the setting of post-transplant lymphoproliferative disorders. Clin Transplant. 23(6):794-9, 2009
Borhani AA et al: Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. Radiographics. 29(4):981-1000; discussion 1000-2, 2009
Cornejo A et al: Intestinal perforation associated with rituximab therapy for post-transplant lymphoproliferative disorder after liver transplantation. Cancer Chemother Pharmacol. 64(4):857-60, 2009
Noraini AR et al: PET-CT as an effective imaging modality in the staging and follow-up of post-transplant lymphoproliferative disorder following solid organ transplantation. Singapore Med J. 50(12):1189-95, 2009
Styczynski J et al: Outcome of treatment of Epstein-Barr virus-related post-transplant lymphoproliferative disorder in hematopoietic stem cell recipients: a comprehensive review of reported cases. Transpl Infect Dis. 11(5):383-92, 2009
Dhillon MS et al: Post-transplant lymphoproliferative disease in liver transplantation. Br J Radiol. 80(953):337-46, 2007
Ulu EM et al: Abdominal computed tomography findings of malignant tumors in patients with solid organ transplants. Transplant Proc. 39(4):1066-70, 2007
Bakker NA et al: PTLD visualization by FDG-PET: improved detection of extranodal localizations. Am J Transplant. 6(8):1984-5, 2006
Bakker NA et al: Early onset post-transplant lymphoproliferative disease is associated with allograft localization. Clin Transplant. 19(3):327-34, 2005
Scarsbrook AF et al: Post-transplantation lymphoproliferative disorder: the spectrum of imaging appearances. Clin Radiol. 60(1):47-55, 2005
Wilde GE et al: Posttransplantation lymphoproliferative disorder in pediatric recipients of solid organ transplants: timing and location of disease. AJR Am J Roentgenol. 185(5):1335-41, 2005
Opelz G et al: Lymphomas after solid organ transplantation: a collaborative transplant study report. Am J Transplant. 4(2):222-30, 2004
Meador TL et al: Imaging features of posttransplantation lymphoproliferative disorder in pancreas transplant recipients. AJR Am J Roentgenol. 174(1):121-4, 2000
Pickhardt PJ et al: Posttransplantation lymphoproliferative disorder of the abdomen: CT evaluation in 51 patients. Radiology. 213(1):73-8, 1999
Pickhardt PJ et al: Abdominal manifestations of posttransplantation lymphoproliferative disorder. AJR Am J Roentgenol. 171(4):1007-13, 1998
Dodd GD 3rd et al: Thoracic and abdominal manifestations of lymphoma occurring in the immunocompromised patient. Radiol Clin North Am. 30(3):597-610, 1992
Heterogeneous group of lymphoproliferative diseases that occur in posttransplant setting (either solid organ or stem cell transplants), ranging from abnormal lymphoid hyperplasias to frank malignancies
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Fluoroscopic Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Kim DH et al: Diagnostic performances of F-18 FDG PET or PET/CT for detection of post-transplant lymphoproliferative disorder: a systematic review and meta-analysis. Nucl Med Commun. 41(6):533-9, 2020
Montes de Jesus FM et al: Diagnostic performance of FDG-PET/CT of post-transplant lymphoproliferative disorder and factors affecting diagnostic yield. Eur J Nucl Med Mol Imaging. 47(3):529-36, 2020
Xu YF et al: Roles of F-18-fluoro-2-deoxy-glucose PET/computed tomography scans in the management of post-transplant lymphoproliferative disease in Pediatric Patient. PET Clin. 15(3):309-19, 2020
Katabathina V et al: Complications of immunosuppressive therapy in solid organ transplantation. Radiol Clin North Am. 54(2):303-19, 2016
Takehana CS et al: (18)F-FDG PET/CT in the management of patients with post-transplant lymphoproliferative disorder. Nucl Med Commun. 35(3):276-81, 2014
Blaes AH et al: Positron emission tomography scanning in the setting of post-transplant lymphoproliferative disorders. Clin Transplant. 23(6):794-9, 2009
Borhani AA et al: Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. Radiographics. 29(4):981-1000; discussion 1000-2, 2009
Cornejo A et al: Intestinal perforation associated with rituximab therapy for post-transplant lymphoproliferative disorder after liver transplantation. Cancer Chemother Pharmacol. 64(4):857-60, 2009
Noraini AR et al: PET-CT as an effective imaging modality in the staging and follow-up of post-transplant lymphoproliferative disorder following solid organ transplantation. Singapore Med J. 50(12):1189-95, 2009
Styczynski J et al: Outcome of treatment of Epstein-Barr virus-related post-transplant lymphoproliferative disorder in hematopoietic stem cell recipients: a comprehensive review of reported cases. Transpl Infect Dis. 11(5):383-92, 2009
Dhillon MS et al: Post-transplant lymphoproliferative disease in liver transplantation. Br J Radiol. 80(953):337-46, 2007
Ulu EM et al: Abdominal computed tomography findings of malignant tumors in patients with solid organ transplants. Transplant Proc. 39(4):1066-70, 2007
Bakker NA et al: PTLD visualization by FDG-PET: improved detection of extranodal localizations. Am J Transplant. 6(8):1984-5, 2006
Bakker NA et al: Early onset post-transplant lymphoproliferative disease is associated with allograft localization. Clin Transplant. 19(3):327-34, 2005
Scarsbrook AF et al: Post-transplantation lymphoproliferative disorder: the spectrum of imaging appearances. Clin Radiol. 60(1):47-55, 2005
Wilde GE et al: Posttransplantation lymphoproliferative disorder in pediatric recipients of solid organ transplants: timing and location of disease. AJR Am J Roentgenol. 185(5):1335-41, 2005
Opelz G et al: Lymphomas after solid organ transplantation: a collaborative transplant study report. Am J Transplant. 4(2):222-30, 2004
Meador TL et al: Imaging features of posttransplantation lymphoproliferative disorder in pancreas transplant recipients. AJR Am J Roentgenol. 174(1):121-4, 2000
Pickhardt PJ et al: Posttransplantation lymphoproliferative disorder of the abdomen: CT evaluation in 51 patients. Radiology. 213(1):73-8, 1999
Pickhardt PJ et al: Abdominal manifestations of posttransplantation lymphoproliferative disorder. AJR Am J Roentgenol. 171(4):1007-13, 1998
Dodd GD 3rd et al: Thoracic and abdominal manifestations of lymphoma occurring in the immunocompromised patient. Radiol Clin North Am. 30(3):597-610, 1992
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