Potentially reversible state of spinal cord edema caused by obstruction or alteration of normal CSF flow pathways
± presence of syrinx
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Gadde JA et al: Anatomical features of the cervical spinal canal in Chiari I deformity with presyrinx: a case-control study. Neuroradiol J. 30(5):405-9, 2017
Nixon JN et al: Presyrinx in a child with acquired Chiari I malformation. Pediatr Radiol. 43(4):506-11, 2013
Battal B et al: Cerebrospinal fluid flow imaging by using phase-contrast MR technique. Br J Radiol. 84(1004):758-65, 2011
Sekula RF Jr et al: The pathogenesis of Chiari I malformation and syringomyelia. Neurol Res. 33(3):232-9, 2011
Shaffer N et al: Cerebrospinal fluid hydrodynamics in type I Chiari malformation. Neurol Res. 33(3):247-60, 2011
Suzuki F et al: Subacute subdural hygroma and presyrinx formation after foramen magnum decompression with duraplasty for Chiari type 1 malformation. Neurol Med Chir (Tokyo). 51(5):389-93, 2011
Bonfield CM et al: Surgical management of post-traumatic syringomyelia. Spine (Phila Pa 1976). 35(21 Suppl):S245-58, 2010
Koyanagi I et al: Pathogenesis of syringomyelia associated with Chiari type 1 malformation: review of evidences and proposal of a new hypothesis. Neurosurg Rev. 33(3):271-84; discussion 284-5, 2010
Fernández AA et al: Malformations of the craniocervical junction (Chiari type I and syringomyelia: classification, diagnosis and treatment). BMC Musculoskelet Disord. 10 Suppl 1:S1, 2009
Ravaglia S et al: Presyrinx in children with Chiari malformations. Neurology. 72(22):1966-7, 2009
Yurube T et al: The vanishment of an intramedullary high-signal intensity lesion at the craniocervical junction after surgical treatment: a case report of the presyrinx state. Spine (Phila Pa 1976). 34(6):E235-9, 2009
Goh S et al: Presyrinx in children with Chiari malformations. Neurology. 71(5):351-6, 2008
Brodbelt A et al: CSF pathways: a review. Br J Neurosurg. 21(5):510-20, 2007
Ikushima I et al: High-resolution constructive interference in a steady state imaging of cervicothoracic adhesive arachnoiditis. J Comput Assist Tomogr. 31(1):143-7, 2007
Gan YC et al: Presyrinx state. J Neurosurg. 105(2 Suppl):156-7; author reply 157-9, 2006
Nair N et al: Cervical cord presyrinx. Br J Neurosurg. 20(3):175-6, 2006
Fischbein NJ et al: The "presyrinx" state: is there a reversible myelopathic condition that may precede syringomyelia? Neurosurg Focus. 8(3):E4, 2000
Milhorat TH: Is reversible enlargement of the spinal cord a presyrinx state? AJNR Am J Neuroradiol. 20(1):21-2, 1999
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Diagnostic Checklist
TERMINOLOGY
Synonyms
Presyrinx state, interstitial cord edema
Definitions
Potentially reversible state of spinal cord edema caused by obstruction or alteration of normal CSF flow pathways
± presence of syrinx
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Gadde JA et al: Anatomical features of the cervical spinal canal in Chiari I deformity with presyrinx: a case-control study. Neuroradiol J. 30(5):405-9, 2017
Nixon JN et al: Presyrinx in a child with acquired Chiari I malformation. Pediatr Radiol. 43(4):506-11, 2013
Battal B et al: Cerebrospinal fluid flow imaging by using phase-contrast MR technique. Br J Radiol. 84(1004):758-65, 2011
Sekula RF Jr et al: The pathogenesis of Chiari I malformation and syringomyelia. Neurol Res. 33(3):232-9, 2011
Shaffer N et al: Cerebrospinal fluid hydrodynamics in type I Chiari malformation. Neurol Res. 33(3):247-60, 2011
Suzuki F et al: Subacute subdural hygroma and presyrinx formation after foramen magnum decompression with duraplasty for Chiari type 1 malformation. Neurol Med Chir (Tokyo). 51(5):389-93, 2011
Bonfield CM et al: Surgical management of post-traumatic syringomyelia. Spine (Phila Pa 1976). 35(21 Suppl):S245-58, 2010
Koyanagi I et al: Pathogenesis of syringomyelia associated with Chiari type 1 malformation: review of evidences and proposal of a new hypothesis. Neurosurg Rev. 33(3):271-84; discussion 284-5, 2010
Fernández AA et al: Malformations of the craniocervical junction (Chiari type I and syringomyelia: classification, diagnosis and treatment). BMC Musculoskelet Disord. 10 Suppl 1:S1, 2009
Ravaglia S et al: Presyrinx in children with Chiari malformations. Neurology. 72(22):1966-7, 2009
Yurube T et al: The vanishment of an intramedullary high-signal intensity lesion at the craniocervical junction after surgical treatment: a case report of the presyrinx state. Spine (Phila Pa 1976). 34(6):E235-9, 2009
Goh S et al: Presyrinx in children with Chiari malformations. Neurology. 71(5):351-6, 2008
Brodbelt A et al: CSF pathways: a review. Br J Neurosurg. 21(5):510-20, 2007
Ikushima I et al: High-resolution constructive interference in a steady state imaging of cervicothoracic adhesive arachnoiditis. J Comput Assist Tomogr. 31(1):143-7, 2007
Gan YC et al: Presyrinx state. J Neurosurg. 105(2 Suppl):156-7; author reply 157-9, 2006
Nair N et al: Cervical cord presyrinx. Br J Neurosurg. 20(3):175-6, 2006
Fischbein NJ et al: The "presyrinx" state: is there a reversible myelopathic condition that may precede syringomyelia? Neurosurg Focus. 8(3):E4, 2000
Milhorat TH: Is reversible enlargement of the spinal cord a presyrinx state? AJNR Am J Neuroradiol. 20(1):21-2, 1999
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