link
Bookmarks
Primary Malignant Bone Tumor
Julia R. Crim, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
10

OVERVIEW

  • General Comments

    • Classification

      PATHOLOGY

      • Routes of Spread

        • General Features

          • Gross Pathology & Surgical Features

            • Microscopic Features

              • Biopsy Considerations

                IMAGING FINDINGS

                • Detection

                  • Predicting Histologic Type of Bone Tumors

                    • Staging

                      • Restaging

                        • Imaging After Surgical Resection

                          CLINICAL ISSUES

                          • Presentation

                            • Cancer History

                              • Treatment Options

                                REPORTING CHECKLIST

                                • Required Consultations

                                  • Staging MR Must Include Entire Lesion

                                    • Preoperative Staging and Restaging Reports Must Include

                                      Selected References

                                      1. American Cancer Society: Key Statistics for Bone Cancer. https://www.cancer.org/cancer/bone-cancer/about/key-statistics.html. Published November 28, 2017. Updated January 8, 2019. Accessed July 17, 2019
                                      2. Siegel RL et al: Cancer statistics, 2018. CA Cancer J Clin. 68(1):7-30, 2018
                                      3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                      4. van Praag Veroniek VM et al: Incidence, outcomes and prognostic factors during 25 years of treatment of chondrosarcomas. Surg Oncol. 27(3):402-8, 2018
                                      5. Crim J et al: Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma? Eur J Radiol. 84(11):2222-30, 2015
                                      6. Fletcher CDM et al: World Health Organization Classification of Tumours of Soft tissue and Bone, 4th Ed. Lyon: IARC Press, 2013
                                      7. Benz MR et al: Treatment monitoring by 18F-FDG PET/CT in patients with sarcomas: interobserver variability of quantitative parameters in treatment-induced changes in histopathologically responding and nonresponding tumors. J Nucl Med. 49(7):1038-46, 2008
                                      8. Eary JF et al: Spatial heterogeneity in sarcoma 18F-FDG uptake as a predictor of patient outcome. J Nucl Med. 49(12):1973-9, 2008
                                      9. Bramer JA et al: Do pathological fractures influence survival and local recurrence rate in bony sarcomas? Eur J Cancer. 43(13):1944-51, 2007
                                      10. Liu PT et al: Anatomically based guidelines for core needle biopsy of bone tumors: implications for limb-sparing surgery. Radiographics. 27(1):189-205; discussion 206, 2007
                                      11. Skeletal Lesions interobserver correlation among expert diagnosticians (SLICED) study group: reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. J Bone Joint Surg Am. 89(10):2113-23, 2007
                                      12. Tateishi U et al: Bone and soft-tissue sarcoma: preoperative staging with fluorine 18 fluorodeoxyglucose PET/CT and conventional imaging. Radiology. 245(3):839-47, 2007
                                      13. Unni KK et al. AFIP Atlas of Tumor Pathology: Tumors of the Bones and Joints. Washington, 2005
                                      14. Mankin HJ et al: Survival data for 648 patients with osteosarcoma treated at one institution. Clin Orthop Relat Res. (429):286-91, 2004
                                      15. Enneking WF et al: A system for the surgical staging of musculoskeletal sarcoma. 1980. Clin Orthop Relat Res. (415):4-18, 2003
                                      Related Anatomy
                                      Loading...
                                      Related Differential Diagnoses
                                      Loading...
                                      References
                                      Tables

                                      Tables

                                      OVERVIEW

                                      • General Comments

                                        • Classification

                                          PATHOLOGY

                                          • Routes of Spread

                                            • General Features

                                              • Gross Pathology & Surgical Features

                                                • Microscopic Features

                                                  • Biopsy Considerations

                                                    IMAGING FINDINGS

                                                    • Detection

                                                      • Predicting Histologic Type of Bone Tumors

                                                        • Staging

                                                          • Restaging

                                                            • Imaging After Surgical Resection

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Cancer History

                                                                  • Treatment Options

                                                                    REPORTING CHECKLIST

                                                                    • Required Consultations

                                                                      • Staging MR Must Include Entire Lesion

                                                                        • Preoperative Staging and Restaging Reports Must Include

                                                                          Selected References

                                                                          1. American Cancer Society: Key Statistics for Bone Cancer. https://www.cancer.org/cancer/bone-cancer/about/key-statistics.html. Published November 28, 2017. Updated January 8, 2019. Accessed July 17, 2019
                                                                          2. Siegel RL et al: Cancer statistics, 2018. CA Cancer J Clin. 68(1):7-30, 2018
                                                                          3. Amin MB et al: AJCC Cancer Staging Manual. 8th Ed. Springer New York, 2017
                                                                          4. van Praag Veroniek VM et al: Incidence, outcomes and prognostic factors during 25 years of treatment of chondrosarcomas. Surg Oncol. 27(3):402-8, 2018
                                                                          5. Crim J et al: Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma? Eur J Radiol. 84(11):2222-30, 2015
                                                                          6. Fletcher CDM et al: World Health Organization Classification of Tumours of Soft tissue and Bone, 4th Ed. Lyon: IARC Press, 2013
                                                                          7. Benz MR et al: Treatment monitoring by 18F-FDG PET/CT in patients with sarcomas: interobserver variability of quantitative parameters in treatment-induced changes in histopathologically responding and nonresponding tumors. J Nucl Med. 49(7):1038-46, 2008
                                                                          8. Eary JF et al: Spatial heterogeneity in sarcoma 18F-FDG uptake as a predictor of patient outcome. J Nucl Med. 49(12):1973-9, 2008
                                                                          9. Bramer JA et al: Do pathological fractures influence survival and local recurrence rate in bony sarcomas? Eur J Cancer. 43(13):1944-51, 2007
                                                                          10. Liu PT et al: Anatomically based guidelines for core needle biopsy of bone tumors: implications for limb-sparing surgery. Radiographics. 27(1):189-205; discussion 206, 2007
                                                                          11. Skeletal Lesions interobserver correlation among expert diagnosticians (SLICED) study group: reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. J Bone Joint Surg Am. 89(10):2113-23, 2007
                                                                          12. Tateishi U et al: Bone and soft-tissue sarcoma: preoperative staging with fluorine 18 fluorodeoxyglucose PET/CT and conventional imaging. Radiology. 245(3):839-47, 2007
                                                                          13. Unni KK et al. AFIP Atlas of Tumor Pathology: Tumors of the Bones and Joints. Washington, 2005
                                                                          14. Mankin HJ et al: Survival data for 648 patients with osteosarcoma treated at one institution. Clin Orthop Relat Res. (429):286-91, 2004
                                                                          15. Enneking WF et al: A system for the surgical staging of musculoskeletal sarcoma. 1980. Clin Orthop Relat Res. (415):4-18, 2003