Primary melanocytoma of cord, meningeal melanocytoma
Definitions
Uncommon neoplasms derived from normal leptomeningeal melanocytes
Morphologic spectrum from low-grade melanocytoma to melanocytic tumor of intermediate differentiation to malignant melanoma
Distinct from other melanotic lesions, such as meningioma, schwannoma, melanoma
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Xie S et al: Primary spinal cord melanocytoma: a case report and review of literature. Int J Clin Exp Pathol. 12(2):669-73, 2019
Yang C et al: Spinal meningeal melanocytomas: clinical manifestations, radiological and pathological characteristics, and surgical outcomes. J Neurooncol. 127(2):279-86, 2016
Foit NA et al: Bifocal extra- and intradural melanocytoma of the spine: case report and literature review. Eur Spine J. 22 Suppl 3:S521-5, 2013
Ali Y et al: Multifocal meningeal melanocytoma: a new pathological entity or the result of leptomeningeal seeding? J Neurosurg. 111(3):488-91, 2009
El-Khashab M et al: Intermediate grade meningeal melanocytoma of cervical spine. Childs Nerv Syst. 25(4):407-10, 2009
Horn EM et al: Surgical treatment for intramedullary spinal cord melanocytomas. J Neurosurg Spine. 9(1):48-54, 2008
Khadilkar UN et al: Primary meningeal melanocytoma. Kathmandu Univ Med J (KUMJ). 6(2):245-7, 2008
Wang F et al: Malignant transformation of spinal meningeal melanocytoma. Case report and review of the literature. J Neurosurg Spine. 6(5):451-4, 2007
Turhan T et al: Spinal meningeal melanocytoma. Report of two cases and review of the literature. J Neurosurg. 100(3 Suppl Spine):287-90, 2004
Brat DJ et al: Primary melanocytic neoplasms of the central nervous systems. Am J Surg Pathol. 23(7):745-54, 1999
Alameda F et al: Meningeal melanocytoma: a case report and literature review. Ultrastruct Pathol. 22(4):349-56, 1998
Chen CJ et al: Intracranial meningeal melanocytoma: CT and MRI. Neuroradiology. 39(11):811-4, 1997
Czarnecki EJ et al: MR of spinal meningeal melanocytoma. AJNR Am J Neuroradiol. 18(1):180-2, 1997
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Synonyms
Primary melanocytoma of cord, meningeal melanocytoma
Definitions
Uncommon neoplasms derived from normal leptomeningeal melanocytes
Morphologic spectrum from low-grade melanocytoma to melanocytic tumor of intermediate differentiation to malignant melanoma
Distinct from other melanotic lesions, such as meningioma, schwannoma, melanoma
IMAGING
General Features
CT Findings
MR Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Xie S et al: Primary spinal cord melanocytoma: a case report and review of literature. Int J Clin Exp Pathol. 12(2):669-73, 2019
Yang C et al: Spinal meningeal melanocytomas: clinical manifestations, radiological and pathological characteristics, and surgical outcomes. J Neurooncol. 127(2):279-86, 2016
Foit NA et al: Bifocal extra- and intradural melanocytoma of the spine: case report and literature review. Eur Spine J. 22 Suppl 3:S521-5, 2013
Ali Y et al: Multifocal meningeal melanocytoma: a new pathological entity or the result of leptomeningeal seeding? J Neurosurg. 111(3):488-91, 2009
El-Khashab M et al: Intermediate grade meningeal melanocytoma of cervical spine. Childs Nerv Syst. 25(4):407-10, 2009
Horn EM et al: Surgical treatment for intramedullary spinal cord melanocytomas. J Neurosurg Spine. 9(1):48-54, 2008
Khadilkar UN et al: Primary meningeal melanocytoma. Kathmandu Univ Med J (KUMJ). 6(2):245-7, 2008
Wang F et al: Malignant transformation of spinal meningeal melanocytoma. Case report and review of the literature. J Neurosurg Spine. 6(5):451-4, 2007
Turhan T et al: Spinal meningeal melanocytoma. Report of two cases and review of the literature. J Neurosurg. 100(3 Suppl Spine):287-90, 2004
Brat DJ et al: Primary melanocytic neoplasms of the central nervous systems. Am J Surg Pathol. 23(7):745-54, 1999
Alameda F et al: Meningeal melanocytoma: a case report and literature review. Ultrastruct Pathol. 22(4):349-56, 1998
Chen CJ et al: Intracranial meningeal melanocytoma: CT and MRI. Neuroradiology. 39(11):811-4, 1997
Czarnecki EJ et al: MR of spinal meningeal melanocytoma. AJNR Am J Neuroradiol. 18(1):180-2, 1997
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