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Primary Mesenteric Adenitis
Michael R. Aquino, MD, MHSc
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Mesenteric lymphadenitis
            • Definitions

              • Self-limited benign inflammation of lymph nodes in bowel mesentery; diagnosis of exclusion
              • Secondary mesenteric adenitis refers to lymphadenopathy associated with detectable intraabdominal inflammatory process, commonly Crohn disease or infectious ileitis
              • Most frequent alternative diagnosis to appendicitis

            IMAGING

            • General Features

              • Radiographic Findings

                • Ultrasonographic Findings

                  • CT Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Patel NB et al: Evaluating the patient with right lower quadrant pain. Radiol Clin North Am. 53(6):1159-70, 2015
                                      2. Millet I et al: Infection of the right iliac fossa. Diagn Interv Imaging. 93(6):441-52, 2012
                                      3. Toorenvliet B et al: Clinical differentiation between acute appendicitis and acute mesenteric lymphadenitis in children. Eur J Pediatr Surg. 21(2):120-3, 2011
                                      4. Sung T et al: Clinical and imaging mimickers of acute appendicitis in the pediatric population. AJR Am J Roentgenol. 186(1):67-74, 2006
                                      5. Karmazyn B et al: Mesenteric lymph nodes in children: what is normal? Pediatr Radiol. 35(8):774-7, 2005
                                      6. Lee CC et al: Mesenteric adenitis caused by Salmonella enterica serovar Enteritidis. J Formos Med Assoc. 103(6):463-6, 2004
                                      7. Likitnukul S et al: Appendicitis-like syndrome owing to mesenteric adenitis caused by Salmonella typhi. Ann Trop Paediatr. 22(1):97-9, 2002
                                      8. Macari M et al: Mesenteric adenitis: CT diagnosis of primary versus secondary causes, incidence, and clinical significance in pediatric and adult patients. AJR Am J Roentgenol. 178(4):853-8, 2002
                                      9. Lamps LW et al: The role of Yersinia enterocolitica and Yersinia pseudotuberculosis in granulomatous appendicitis: a histologic and molecular study. Am J Surg Pathol. 25(4):508-15, 2001
                                      10. Lee JH et al: The etiology and clinical characteristics of mesenteric adenitis in Korean adults. J Korean Med Sci. 12(2):105-10, 1997
                                      11. Rao PM et al: CT diagnosis of mesenteric adenitis. Radiology. 202(1):145-9, 1997
                                      12. Van Noyen R et al: Causative role of Yersinia and other enteric pathogens in the appendicular syndrome. Eur J Clin Microbiol Infect Dis. 10(9):735-41, 1991
                                      13. Puylaert JB: Mesenteric adenitis and acute terminal ileitis: US evaluation using graded compression. Radiology. 161(3):691-5, 1986
                                      14. Saebo A: The Yersinia enterocolitica infection in acute abdominal surgery. A clinical study with a 5-year follow-up period. Ann Surg. 198(6):760-5, 1983
                                      15. Schapers RF et al: Mesenteric lymphadenitis due to Yersinia enterocolitica. Virchows Arch A Pathol Anat Histol. 390(2):127-38, 1981
                                      16. Gilmore OJ et al: Appendicitis and mimicking conditions. A prospective study. Lancet. 2(7932):421-4, 1975
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Mesenteric lymphadenitis
                                                • Definitions

                                                  • Self-limited benign inflammation of lymph nodes in bowel mesentery; diagnosis of exclusion
                                                  • Secondary mesenteric adenitis refers to lymphadenopathy associated with detectable intraabdominal inflammatory process, commonly Crohn disease or infectious ileitis
                                                  • Most frequent alternative diagnosis to appendicitis

                                                IMAGING

                                                • General Features

                                                  • Radiographic Findings

                                                    • Ultrasonographic Findings

                                                      • CT Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Patel NB et al: Evaluating the patient with right lower quadrant pain. Radiol Clin North Am. 53(6):1159-70, 2015
                                                                          2. Millet I et al: Infection of the right iliac fossa. Diagn Interv Imaging. 93(6):441-52, 2012
                                                                          3. Toorenvliet B et al: Clinical differentiation between acute appendicitis and acute mesenteric lymphadenitis in children. Eur J Pediatr Surg. 21(2):120-3, 2011
                                                                          4. Sung T et al: Clinical and imaging mimickers of acute appendicitis in the pediatric population. AJR Am J Roentgenol. 186(1):67-74, 2006
                                                                          5. Karmazyn B et al: Mesenteric lymph nodes in children: what is normal? Pediatr Radiol. 35(8):774-7, 2005
                                                                          6. Lee CC et al: Mesenteric adenitis caused by Salmonella enterica serovar Enteritidis. J Formos Med Assoc. 103(6):463-6, 2004
                                                                          7. Likitnukul S et al: Appendicitis-like syndrome owing to mesenteric adenitis caused by Salmonella typhi. Ann Trop Paediatr. 22(1):97-9, 2002
                                                                          8. Macari M et al: Mesenteric adenitis: CT diagnosis of primary versus secondary causes, incidence, and clinical significance in pediatric and adult patients. AJR Am J Roentgenol. 178(4):853-8, 2002
                                                                          9. Lamps LW et al: The role of Yersinia enterocolitica and Yersinia pseudotuberculosis in granulomatous appendicitis: a histologic and molecular study. Am J Surg Pathol. 25(4):508-15, 2001
                                                                          10. Lee JH et al: The etiology and clinical characteristics of mesenteric adenitis in Korean adults. J Korean Med Sci. 12(2):105-10, 1997
                                                                          11. Rao PM et al: CT diagnosis of mesenteric adenitis. Radiology. 202(1):145-9, 1997
                                                                          12. Van Noyen R et al: Causative role of Yersinia and other enteric pathogens in the appendicular syndrome. Eur J Clin Microbiol Infect Dis. 10(9):735-41, 1991
                                                                          13. Puylaert JB: Mesenteric adenitis and acute terminal ileitis: US evaluation using graded compression. Radiology. 161(3):691-5, 1986
                                                                          14. Saebo A: The Yersinia enterocolitica infection in acute abdominal surgery. A clinical study with a 5-year follow-up period. Ann Surg. 198(6):760-5, 1983
                                                                          15. Schapers RF et al: Mesenteric lymphadenitis due to Yersinia enterocolitica. Virchows Arch A Pathol Anat Histol. 390(2):127-38, 1981
                                                                          16. Gilmore OJ et al: Appendicitis and mimicking conditions. A prospective study. Lancet. 2(7932):421-4, 1975