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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Pseudomyxoma peritonei (PMP)
Definitions
- Diffuse intraperitoneal accumulation of gelatinous mucinous implants due to rupture of appendiceal mucinous neoplasm
- Terminology is highly debated and variable, and some authors also use term PMP for mucinous dissemination after rupture of mucin-producing tumors at other sites (i.e., colon, stomach, fallopian tube, ovary, urachus, etc.)
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Radiographic Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Bartlett DJ et al: Mucinous appendiceal neoplasms: classification, imaging, and HIPEC. Abdom Radiol (NY). 44(5):1686-702, 2019
- Rizvi SA et al: Approach to pseudomyxoma peritonei. World J Gastrointest Surg. 10(5):49-56, 2018
- Dubreuil J et al: 18F-FDG-PET/CT of peritoneal tumors: a pictorial essay. Nucl Med Commun. 38(1):1-9, 2017
- Leonards LM et al: Neoplasms of the appendix: pictorial review with clinical and pathologic correlation. Radiographics. 37(4):1059-83, 2017
- Tiselius C et al: Computed tomography follow-up assessment of patients with low-grade appendiceal mucinous neoplasms: evaluation of risk for pseudomyxoma peritonei. Ann Surg Oncol. 24(7):1778-82, 2017
- Carr NJ: Current concepts in pseudomyxoma peritonei. Ann Pathol. 34(1):9-13, 2014
- Diop AD et al: CT imaging of peritoneal carcinomatosis and its mimics. Diagn Interv Imaging. 95(9):861-72, 2014
- Vicens RA et al: Multimodality imaging of common and uncommon peritoneal diseases: a review for radiologists. Abdom Imaging. 40(2):436-56, 2014
- Buell-Gutbrod R et al: Pathologic diagnosis, origin, and natural history of pseudomyxoma peritonei. Am Soc Clin Oncol Educ Book. 221-5, 2013
- Faris JE et al: Controversy and consensus on the management of patients with pseudomyxoma peritonei. Curr Treat Options Oncol. 14(3):365-73, 2013
- Tirumani SH et al: Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review. Cancer Imaging. 13:14-25, 2013
- Krause J et al: Ultrasonography findings and tumour quantification in patients with pseudomyxoma peritonei. Eur J Radiol. 81(4):648-51, 2012
- Que Y et al: Pseudomyxoma peritonei: some different sonographic findings. Abdom Imaging. 37(5):843-8, 2012
- Bevan KE et al: Pseudomyxoma peritonei. World J Gastrointest Oncol. 2(1):44-50, 2010
- Cioppa T et al: Cytoreduction and hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from pseudomyxoma peritonei. World J Gastroenterol. 14(44):6817-23, 2008
- Koyama T et al: Secondary ovarian tumors: spectrum of CT and MR features with pathologic correlation. Abdom Imaging. 32(6):784-95, 2007
- Jacquemin G et al: Pseudomyxoma peritonei: review on a cluster of peritoneal mucinous diseases. Acta Chir Belg. 105(2):127-33, 2005
- Takeuchi M et al: Imaging findings of urachal mucinous cystadenocarcinoma associated with pseudomyxoma peritonei. Acta Radiol. 45(3):348-50, 2004
- Hanbidge AE et al: US of the peritoneum. Radiographics. 23(3):663-84; discussion 684-5, 2003
- Harshen R et al: Pseudomyxoma peritonei. Clin Oncol (R Coll Radiol). 15(2):73-7, 2003
- Lo NS et al: Mucinous cystadenocarcinoma of the appendix. The controversy persists: a review. Hepatogastroenterology. 50(50):432-7, 2003
- Moran BJ et al: The etiology, clinical presentation, and management of pseudomyxoma peritonei. Surg Oncol Clin N Am. 12(3):585-603, 2003
- Park CM et al: Recurrent ovarian malignancy: patterns and spectrum of imaging findings. Abdom Imaging. 28(3):404-15, 2003
- Pickhardt PJ et al: Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation. Radiographics. 23(3):645-62, 2003
- van Ruth S et al: Pseudomyxoma peritonei: a review of 62 cases. Eur J Surg Oncol. 29(8):682-8, 2003
- Butterworth SA et al: Morbidity and mortality associated with intraperitoneal chemotherapy for Pseudomyxoma peritonei. Am J Surg. 183(5):529-32, 2002
- Georgescu S et al: Mucinous digestive tumors. Case reports and review of the literature. Rom J Gastroenterol. 11(3):213-8, 2002
- Nakao A et al: Appendiceal mucocele of mucinous cystadenocarcinoma with a cutaneous fistula. J Int Med Res. 30(4):452-6, 2002
- Rose MG et al: Typical clinical and radiographic findings in a patient with longstanding malignant pseudomyxoma peritonei secondary to a mucinous adenocarcinoma. Clin Colorectal Cancer. 2(1):59-60, 2002
- Shappell HW et al: Diagnostic criteria and behavior of ovarian seromucinous (endocervical-type mucinous and mixed cell-type) tumors: atypical proliferative (borderline) tumors, intraepithelial, microinvasive, and invasive carcinomas. Am J Surg Pathol. 26(12):1529-41, 2002
- Sulkin TV et al: CT in pseudomyxoma peritonei: a review of 17 cases. Clin Radiol. 57(7):608-13, 2002
- van Ruth S et al: Prognostic value of baseline and serial carcinoembryonic antigen and carbohydrate antigen 19.9 measurements in patients with pseudomyxoma peritonei treated with cytoreduction and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol. 9(10):961-7, 2002
- Elias DM et al: Intraperitoneal chemohyperthermia: rationale, technique, indications, and results. Surg Oncol Clin N Am. 10(4):915-33, xi, 2001
- Sherer DM et al: Pseudomyxoma peritonei: a review of current literature. Gynecol Obstet Invest. 51(2):73-80, 2001
- Witkamp AJ et al: Rationale and techniques of intra-operative hyperthermic intraperitoneal chemotherapy. Cancer Treat Rev. 27(6):365-74, 2001
- Yan H et al: Histopathologic analysis in 46 patients with pseudomyxoma peritonei syndrome: failure versus success with a second-look operation. Mod Pathol. 14(3):164-71, 2001
- Esquivel J et al: Clinical presentation of the pseudomyxoma peritonei syndrome. Br J Surg. 87(10):1414-8, 2000
- Nawaz A et al: Pseudomyxoma peritonei manifesting as intestinal obstruction. South Med J. 93(9):891-3, 2000
- Pestieau SR et al: Pleural extension of mucinous tumor in patients with pseudomyxoma peritonei syndrome. Ann Surg Oncol. 7(3):199-203, 2000
- Hosch WP et al: Therapy of pseudomyxoma peritonei of appendiceal origin--surgical resection and intraperitoneal chemotherapy. Z Gastroenterol. 37(7):615-22, 1999
- Wirtzfeld DA et al: Disseminated peritoneal adenomucinosis: a critical review. Ann Surg Oncol. 6(8):797-801, 1999
- Hinson FL et al: Pseudomyxoma peritonei. Br J Surg. 85(10):1332-9, 1998
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Pseudomyxoma peritonei (PMP)
Definitions
- Diffuse intraperitoneal accumulation of gelatinous mucinous implants due to rupture of appendiceal mucinous neoplasm
- Terminology is highly debated and variable, and some authors also use term PMP for mucinous dissemination after rupture of mucin-producing tumors at other sites (i.e., colon, stomach, fallopian tube, ovary, urachus, etc.)
IMAGING
General Features
CT Findings
MR Findings
Nuclear Medicine Findings
Radiographic Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Bartlett DJ et al: Mucinous appendiceal neoplasms: classification, imaging, and HIPEC. Abdom Radiol (NY). 44(5):1686-702, 2019
- Rizvi SA et al: Approach to pseudomyxoma peritonei. World J Gastrointest Surg. 10(5):49-56, 2018
- Dubreuil J et al: 18F-FDG-PET/CT of peritoneal tumors: a pictorial essay. Nucl Med Commun. 38(1):1-9, 2017
- Leonards LM et al: Neoplasms of the appendix: pictorial review with clinical and pathologic correlation. Radiographics. 37(4):1059-83, 2017
- Tiselius C et al: Computed tomography follow-up assessment of patients with low-grade appendiceal mucinous neoplasms: evaluation of risk for pseudomyxoma peritonei. Ann Surg Oncol. 24(7):1778-82, 2017
- Carr NJ: Current concepts in pseudomyxoma peritonei. Ann Pathol. 34(1):9-13, 2014
- Diop AD et al: CT imaging of peritoneal carcinomatosis and its mimics. Diagn Interv Imaging. 95(9):861-72, 2014
- Vicens RA et al: Multimodality imaging of common and uncommon peritoneal diseases: a review for radiologists. Abdom Imaging. 40(2):436-56, 2014
- Buell-Gutbrod R et al: Pathologic diagnosis, origin, and natural history of pseudomyxoma peritonei. Am Soc Clin Oncol Educ Book. 221-5, 2013
- Faris JE et al: Controversy and consensus on the management of patients with pseudomyxoma peritonei. Curr Treat Options Oncol. 14(3):365-73, 2013
- Tirumani SH et al: Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review. Cancer Imaging. 13:14-25, 2013
- Krause J et al: Ultrasonography findings and tumour quantification in patients with pseudomyxoma peritonei. Eur J Radiol. 81(4):648-51, 2012
- Que Y et al: Pseudomyxoma peritonei: some different sonographic findings. Abdom Imaging. 37(5):843-8, 2012
- Bevan KE et al: Pseudomyxoma peritonei. World J Gastrointest Oncol. 2(1):44-50, 2010
- Cioppa T et al: Cytoreduction and hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from pseudomyxoma peritonei. World J Gastroenterol. 14(44):6817-23, 2008
- Koyama T et al: Secondary ovarian tumors: spectrum of CT and MR features with pathologic correlation. Abdom Imaging. 32(6):784-95, 2007
- Jacquemin G et al: Pseudomyxoma peritonei: review on a cluster of peritoneal mucinous diseases. Acta Chir Belg. 105(2):127-33, 2005
- Takeuchi M et al: Imaging findings of urachal mucinous cystadenocarcinoma associated with pseudomyxoma peritonei. Acta Radiol. 45(3):348-50, 2004
- Hanbidge AE et al: US of the peritoneum. Radiographics. 23(3):663-84; discussion 684-5, 2003
- Harshen R et al: Pseudomyxoma peritonei. Clin Oncol (R Coll Radiol). 15(2):73-7, 2003
- Lo NS et al: Mucinous cystadenocarcinoma of the appendix. The controversy persists: a review. Hepatogastroenterology. 50(50):432-7, 2003
- Moran BJ et al: The etiology, clinical presentation, and management of pseudomyxoma peritonei. Surg Oncol Clin N Am. 12(3):585-603, 2003
- Park CM et al: Recurrent ovarian malignancy: patterns and spectrum of imaging findings. Abdom Imaging. 28(3):404-15, 2003
- Pickhardt PJ et al: Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation. Radiographics. 23(3):645-62, 2003
- van Ruth S et al: Pseudomyxoma peritonei: a review of 62 cases. Eur J Surg Oncol. 29(8):682-8, 2003
- Butterworth SA et al: Morbidity and mortality associated with intraperitoneal chemotherapy for Pseudomyxoma peritonei. Am J Surg. 183(5):529-32, 2002
- Georgescu S et al: Mucinous digestive tumors. Case reports and review of the literature. Rom J Gastroenterol. 11(3):213-8, 2002
- Nakao A et al: Appendiceal mucocele of mucinous cystadenocarcinoma with a cutaneous fistula. J Int Med Res. 30(4):452-6, 2002
- Rose MG et al: Typical clinical and radiographic findings in a patient with longstanding malignant pseudomyxoma peritonei secondary to a mucinous adenocarcinoma. Clin Colorectal Cancer. 2(1):59-60, 2002
- Shappell HW et al: Diagnostic criteria and behavior of ovarian seromucinous (endocervical-type mucinous and mixed cell-type) tumors: atypical proliferative (borderline) tumors, intraepithelial, microinvasive, and invasive carcinomas. Am J Surg Pathol. 26(12):1529-41, 2002
- Sulkin TV et al: CT in pseudomyxoma peritonei: a review of 17 cases. Clin Radiol. 57(7):608-13, 2002
- van Ruth S et al: Prognostic value of baseline and serial carcinoembryonic antigen and carbohydrate antigen 19.9 measurements in patients with pseudomyxoma peritonei treated with cytoreduction and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol. 9(10):961-7, 2002
- Elias DM et al: Intraperitoneal chemohyperthermia: rationale, technique, indications, and results. Surg Oncol Clin N Am. 10(4):915-33, xi, 2001
- Sherer DM et al: Pseudomyxoma peritonei: a review of current literature. Gynecol Obstet Invest. 51(2):73-80, 2001
- Witkamp AJ et al: Rationale and techniques of intra-operative hyperthermic intraperitoneal chemotherapy. Cancer Treat Rev. 27(6):365-74, 2001
- Yan H et al: Histopathologic analysis in 46 patients with pseudomyxoma peritonei syndrome: failure versus success with a second-look operation. Mod Pathol. 14(3):164-71, 2001
- Esquivel J et al: Clinical presentation of the pseudomyxoma peritonei syndrome. Br J Surg. 87(10):1414-8, 2000
- Nawaz A et al: Pseudomyxoma peritonei manifesting as intestinal obstruction. South Med J. 93(9):891-3, 2000
- Pestieau SR et al: Pleural extension of mucinous tumor in patients with pseudomyxoma peritonei syndrome. Ann Surg Oncol. 7(3):199-203, 2000
- Hosch WP et al: Therapy of pseudomyxoma peritonei of appendiceal origin--surgical resection and intraperitoneal chemotherapy. Z Gastroenterol. 37(7):615-22, 1999
- Wirtzfeld DA et al: Disseminated peritoneal adenomucinosis: a critical review. Ann Surg Oncol. 6(8):797-801, 1999
- Hinson FL et al: Pseudomyxoma peritonei. Br J Surg. 85(10):1332-9, 1998
