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Pulmonary Arterial Hypertension
Brett W. Carter, MD; Gerald F. Abbott, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Pulmonary hypertension (PH)
              • Pulmonary arterial hypertension (PAH)
            • Definitions

              • Mean pulmonary artery (PA) pressure > 25 mm Hg at rest
                • > 30 mm Hg during exercise
              • Mean capillary wedge pressure and left ventricular end-diastolic pressure typically < 15 mm Hg

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          • Echocardiographic Findings

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Staging, Grading, & Classification

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Badesch DB et al: Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest. 137(2):376-87, 2010
                                                2. Sanz J et al: Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. Radiology. 243(1):70-9, 2007
                                                3. Lantuéjoul S et al: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: a clinicopathologic study of 35 cases. Am J Surg Pathol. 30(7):850-7, 2006
                                                4. Bossone E et al: Pulmonary arterial hypertension: the key role of echocardiography. Chest. 127(5):1836-43, 2005
                                                5. Resten A et al: Pulmonary arterial hypertension: thin-section CT predictors of epoprostenol therapy failure. Radiology. 222(3):782-8, 2002
                                                6. Frazier AA et al: From the archives of the AFIP: pulmonary vasculature: hypertension and infarction. Radiographics. 20(2):491-524; quiz 530-1, 532, 2000
                                                7. Sherrick AD et al: Mosaic pattern of lung attenuation on CT scans: frequency among patients with pulmonary artery hypertension of different causes. AJR Am J Roentgenol. 169(1):79-82, 1997
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          TERMINOLOGY

                                                          • Abbreviations

                                                            • Pulmonary hypertension (PH)
                                                            • Pulmonary arterial hypertension (PAH)
                                                          • Definitions

                                                            • Mean pulmonary artery (PA) pressure > 25 mm Hg at rest
                                                              • > 30 mm Hg during exercise
                                                            • Mean capillary wedge pressure and left ventricular end-diastolic pressure typically < 15 mm Hg

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Angiographic Findings

                                                                    • Nuclear Medicine Findings

                                                                      • Imaging Recommendations

                                                                        • Echocardiographic Findings

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Staging, Grading, & Classification

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Badesch DB et al: Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest. 137(2):376-87, 2010
                                                                                              2. Sanz J et al: Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. Radiology. 243(1):70-9, 2007
                                                                                              3. Lantuéjoul S et al: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: a clinicopathologic study of 35 cases. Am J Surg Pathol. 30(7):850-7, 2006
                                                                                              4. Bossone E et al: Pulmonary arterial hypertension: the key role of echocardiography. Chest. 127(5):1836-43, 2005
                                                                                              5. Resten A et al: Pulmonary arterial hypertension: thin-section CT predictors of epoprostenol therapy failure. Radiology. 222(3):782-8, 2002
                                                                                              6. Frazier AA et al: From the archives of the AFIP: pulmonary vasculature: hypertension and infarction. Radiographics. 20(2):491-524; quiz 530-1, 532, 2000
                                                                                              7. Sherrick AD et al: Mosaic pattern of lung attenuation on CT scans: frequency among patients with pulmonary artery hypertension of different causes. AJR Am J Roentgenol. 169(1):79-82, 1997