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Pulmonary Artery Hypertension
Brett W. Carter, MD, CPPS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Pulmonary artery hypertension (PAH)
              • Pulmonary hypertension (PH)
              • Pulmonary artery (PA)
            • Definitions

              • Mean PA pressure > 25 mm Hg at rest
                • > 30 mm Hg during exercise
              • Mean capillary wedge pressure and left ventricular end-diastolic pressure typically < 15 mm Hg

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Echocardiographic Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • Staging, Grading, & Classification

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Altschul E et al: Imaging of pulmonary hypertension: pictorial essay. Chest. 156(2):211-27, 2019
                                              2. Aluja Jaramillo F et al: Approach to pulmonary hypertension: from CT to clinical diagnosis. Radiographics. 38(2):357-73, 2018
                                              3. Foshat M et al: The evolving classification of pulmonary hypertension. Arch Pathol Lab Med. 141(5):696-703, 2017
                                              4. Badesch DB et al: Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest. 137(2):376-87, 2010
                                              5. Sanz J et al: Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. Radiology. 243(1):70-9, 2007
                                              6. Lantuéjoul S et al: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: a clinicopathologic study of 35 cases. Am J Surg Pathol. 30(7):850-7, 2006
                                              7. Bossone E et al: Pulmonary arterial hypertension: the key role of echocardiography. Chest. 127(5):1836-43, 2005
                                              8. Resten A et al: Pulmonary arterial hypertension: thin-section CT predictors of epoprostenol therapy failure. Radiology. 222(3):782-8, 2002
                                              9. Frazier AA et al: From the archives of the AFIP: pulmonary vasculature: hypertension and infarction. Radiographics. 20(2):491-524; quiz 530-1, 532, 2000
                                              10. Sherrick AD et al: Mosaic pattern of lung attenuation on CT scans: frequency among patients with pulmonary artery hypertension of different causes. AJR Am J Roentgenol. 169(1):79-82, 1997
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Pulmonary artery hypertension (PAH)
                                                          • Pulmonary hypertension (PH)
                                                          • Pulmonary artery (PA)
                                                        • Definitions

                                                          • Mean PA pressure > 25 mm Hg at rest
                                                            • > 30 mm Hg during exercise
                                                          • Mean capillary wedge pressure and left ventricular end-diastolic pressure typically < 15 mm Hg

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Angiographic Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Echocardiographic Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • Staging, Grading, & Classification

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Altschul E et al: Imaging of pulmonary hypertension: pictorial essay. Chest. 156(2):211-27, 2019
                                                                                          2. Aluja Jaramillo F et al: Approach to pulmonary hypertension: from CT to clinical diagnosis. Radiographics. 38(2):357-73, 2018
                                                                                          3. Foshat M et al: The evolving classification of pulmonary hypertension. Arch Pathol Lab Med. 141(5):696-703, 2017
                                                                                          4. Badesch DB et al: Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry. Chest. 137(2):376-87, 2010
                                                                                          5. Sanz J et al: Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging. Radiology. 243(1):70-9, 2007
                                                                                          6. Lantuéjoul S et al: Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: a clinicopathologic study of 35 cases. Am J Surg Pathol. 30(7):850-7, 2006
                                                                                          7. Bossone E et al: Pulmonary arterial hypertension: the key role of echocardiography. Chest. 127(5):1836-43, 2005
                                                                                          8. Resten A et al: Pulmonary arterial hypertension: thin-section CT predictors of epoprostenol therapy failure. Radiology. 222(3):782-8, 2002
                                                                                          9. Frazier AA et al: From the archives of the AFIP: pulmonary vasculature: hypertension and infarction. Radiographics. 20(2):491-524; quiz 530-1, 532, 2000
                                                                                          10. Sherrick AD et al: Mosaic pattern of lung attenuation on CT scans: frequency among patients with pulmonary artery hypertension of different causes. AJR Am J Roentgenol. 169(1):79-82, 1997