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Pulmonary Hamartoma
Terrance Healey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Chondromatous hamartoma
                • Mesenchymoma
              • Definitions

                • Derived from "hamartia," Greek work for "error"
                • Benign pulmonary neoplasm containing varying amounts of a variety of tissues
                  • Cartilage
                  • Fat
                  • Connective tissue
                  • Smooth muscle
                  • Epithelial-lined clefts

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Diagnosis

                                            • Treatment

                                              DIAGNOSTIC CHECKLIST

                                              • Consider

                                                • Image Interpretation Pearls

                                                  • Reporting Tips

                                                    Selected References

                                                    1. Gleeson T et al: Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation. J Med Imaging Radiat Oncol. 57(5):534-43, 2013
                                                    2. Khan AN et al: The calcified lung nodule: What does it mean? Ann Thorac Med. 5(2):67-79, 2010
                                                    3. Kim SA et al: Bronchoscopic features and bronchoscopic intervention for endobronchial hamartoma. Respirology. 15(1):150-4, 2010
                                                    4. Park CM et al: Images in clinical medicine. "Popcorn" calcifications in a pulmonary chondroid hamartoma. N Engl J Med. 360(12):e17, 2009
                                                    5. De Cicco C et al: Imaging of lung hamartomas by multidetector computed tomography and positron emission tomography. Ann Thorac Surg. 86(6):1769-72, 2008
                                                    6. Guo W et al: Surgical treatment and outcome of pulmonary hamartoma: a retrospective study of 20-year experience. J Exp Clin Cancer Res. 27:8, 2008
                                                    7. Park KY et al: Diagnostic efficacy and characteristic feature of MRI in pulmonary hamartoma: comparison with CT, specimen MRI, and pathology. J Comput Assist Tomogr. 32(6):919-25, 2008
                                                    8. Wood B et al: Diagnosis of pulmonary hamartoma by fine needle biopsy. Acta Cytol. 52(4):412-7, 2008
                                                    9. Ludwig C et al: Recurrent hamartoma at the trocar incision site after video-assisted thoracic surgical resection. J Thorac Cardiovasc Surg. 130(2):609-10, 2005
                                                    10. Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
                                                    11. Siegelman SS et al: Pulmonary hamartoma: CT findings. Radiology. 160(2):313-7, 1986
                                                    Related Anatomy
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                                                    Related Differential Diagnoses
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                                                    References
                                                    Tables

                                                    Tables

                                                    KEY FACTS

                                                    • Terminology

                                                      • Imaging

                                                        • Top Differential Diagnoses

                                                          • Pathology

                                                            • Clinical Issues

                                                              • Diagnostic Checklist

                                                                TERMINOLOGY

                                                                • Synonyms

                                                                  • Chondromatous hamartoma
                                                                  • Mesenchymoma
                                                                • Definitions

                                                                  • Derived from "hamartia," Greek work for "error"
                                                                  • Benign pulmonary neoplasm containing varying amounts of a variety of tissues
                                                                    • Cartilage
                                                                    • Fat
                                                                    • Connective tissue
                                                                    • Smooth muscle
                                                                    • Epithelial-lined clefts

                                                                IMAGING

                                                                • General Features

                                                                  • Radiographic Findings

                                                                    • CT Findings

                                                                      • MR Findings

                                                                        • Nuclear Medicine Findings

                                                                          • Imaging Recommendations

                                                                            DIFFERENTIAL DIAGNOSIS

                                                                              PATHOLOGY

                                                                              • General Features

                                                                                • Staging, Grading, & Classification

                                                                                  • Gross Pathologic & Surgical Features

                                                                                    • Microscopic Features

                                                                                      CLINICAL ISSUES

                                                                                      • Presentation

                                                                                        • Demographics

                                                                                          • Natural History & Prognosis

                                                                                            • Diagnosis

                                                                                              • Treatment

                                                                                                DIAGNOSTIC CHECKLIST

                                                                                                • Consider

                                                                                                  • Image Interpretation Pearls

                                                                                                    • Reporting Tips

                                                                                                      Selected References

                                                                                                      1. Gleeson T et al: Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation. J Med Imaging Radiat Oncol. 57(5):534-43, 2013
                                                                                                      2. Khan AN et al: The calcified lung nodule: What does it mean? Ann Thorac Med. 5(2):67-79, 2010
                                                                                                      3. Kim SA et al: Bronchoscopic features and bronchoscopic intervention for endobronchial hamartoma. Respirology. 15(1):150-4, 2010
                                                                                                      4. Park CM et al: Images in clinical medicine. "Popcorn" calcifications in a pulmonary chondroid hamartoma. N Engl J Med. 360(12):e17, 2009
                                                                                                      5. De Cicco C et al: Imaging of lung hamartomas by multidetector computed tomography and positron emission tomography. Ann Thorac Surg. 86(6):1769-72, 2008
                                                                                                      6. Guo W et al: Surgical treatment and outcome of pulmonary hamartoma: a retrospective study of 20-year experience. J Exp Clin Cancer Res. 27:8, 2008
                                                                                                      7. Park KY et al: Diagnostic efficacy and characteristic feature of MRI in pulmonary hamartoma: comparison with CT, specimen MRI, and pathology. J Comput Assist Tomogr. 32(6):919-25, 2008
                                                                                                      8. Wood B et al: Diagnosis of pulmonary hamartoma by fine needle biopsy. Acta Cytol. 52(4):412-7, 2008
                                                                                                      9. Ludwig C et al: Recurrent hamartoma at the trocar incision site after video-assisted thoracic surgical resection. J Thorac Cardiovasc Surg. 130(2):609-10, 2005
                                                                                                      10. Gaerte SC et al: Fat-containing lesions of the chest. Radiographics. 22 Spec No:S61-78, 2002
                                                                                                      11. Siegelman SS et al: Pulmonary hamartoma: CT findings. Radiology. 160(2):313-7, 1986