Peribronchiolar infiltration of stellate nodules that contain Langerhans cells
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Diagnosis
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Radzikowska E: Update on pulmonary Langerhans cell histiocytosis. Front Med (Lausanne). 7:582581, 2020
Shaw B et al: Pulmonary Langerhans cell histiocytosis. Semin Respir Crit Care Med. 41(2):269-79, 2020
Lorillon G et al: How I manage pulmonary Langerhans cell histiocytosis. Eur Respir Rev. 26(145), 2017
Vassallo R et al: Current understanding and management of pulmonary Langerhans cell histiocytosis. Thorax. 72(10):937-45, 2017
Raoof S et al: Cystic lung diseases: algorithmic approach. Chest. 150(4):945-65, 2016
Castoldi MC et al: Pulmonary Langerhans cell histiocytosis: the many faces of presentation at initial CT scan. Insights Imaging. 5(4):483-92, 2014
Seaman DM et al: Diffuse cystic lung disease at high-resolution CT. AJR Am J Roentgenol. 196(6):1305-11, 2011
Seely JM et al: Pulmonary Langerhans cell histiocytosis: a comparative study of computed tomography in children and adults. J Thorac Imaging. 27(1):65-70, 2010
Galvin JR et al: Smoking-related lung disease. J Thorac Imaging. 24(4):274-84, 2009
Krajicek BJ et al: Abnormal fluorodeoxyglucose PET in pulmonary Langerhans cell histiocytosis. Chest. 135(6):1542-9, 2009
Attili AK et al: Smoking-related interstitial lung disease: radiologic-clinical-pathologic correlation. Radiographics. 28(5):1383-96; discussion 1396-8, 2008
Abbott GF et al: From the archives of the AFIP: pulmonary Langerhans cell histiocytosis. Radiographics. 24(3):821-41, 2004
Vassallo R et al: Pulmonary Langerhans'-cell histiocytosis. N Engl J Med. 342(26):1969-78, 2000
Brauner MW et al: Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans. Radiology. 204(2):497-502, 1997
Moore AD et al: Pulmonary histiocytosis X: comparison of radiographic and CT findings. Radiology. 172(1):249-54, 1989
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Pulmonary Langerhans cell histiocytosis (PLCH)
Definitions
Peribronchiolar infiltration of stellate nodules that contain Langerhans cells
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Diagnosis
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Radzikowska E: Update on pulmonary Langerhans cell histiocytosis. Front Med (Lausanne). 7:582581, 2020
Shaw B et al: Pulmonary Langerhans cell histiocytosis. Semin Respir Crit Care Med. 41(2):269-79, 2020
Lorillon G et al: How I manage pulmonary Langerhans cell histiocytosis. Eur Respir Rev. 26(145), 2017
Vassallo R et al: Current understanding and management of pulmonary Langerhans cell histiocytosis. Thorax. 72(10):937-45, 2017
Raoof S et al: Cystic lung diseases: algorithmic approach. Chest. 150(4):945-65, 2016
Castoldi MC et al: Pulmonary Langerhans cell histiocytosis: the many faces of presentation at initial CT scan. Insights Imaging. 5(4):483-92, 2014
Seaman DM et al: Diffuse cystic lung disease at high-resolution CT. AJR Am J Roentgenol. 196(6):1305-11, 2011
Seely JM et al: Pulmonary Langerhans cell histiocytosis: a comparative study of computed tomography in children and adults. J Thorac Imaging. 27(1):65-70, 2010
Galvin JR et al: Smoking-related lung disease. J Thorac Imaging. 24(4):274-84, 2009
Krajicek BJ et al: Abnormal fluorodeoxyglucose PET in pulmonary Langerhans cell histiocytosis. Chest. 135(6):1542-9, 2009
Attili AK et al: Smoking-related interstitial lung disease: radiologic-clinical-pathologic correlation. Radiographics. 28(5):1383-96; discussion 1396-8, 2008
Abbott GF et al: From the archives of the AFIP: pulmonary Langerhans cell histiocytosis. Radiographics. 24(3):821-41, 2004
Vassallo R et al: Pulmonary Langerhans'-cell histiocytosis. N Engl J Med. 342(26):1969-78, 2000
Brauner MW et al: Pulmonary Langerhans cell histiocytosis: evolution of lesions on CT scans. Radiology. 204(2):497-502, 1997
Moore AD et al: Pulmonary histiocytosis X: comparison of radiographic and CT findings. Radiology. 172(1):249-54, 1989
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