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Radiation Esophagitis
Michael P. Federle, MD, FACR
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        TERMINOLOGY

        • Abbreviations

          • Radiation esophagitis (RE)
        • Definitions

          • Inflammation of esophageal mucosa and wall induced by curative and palliative radiotherapy (RT)

        IMAGING

        • General Features

          • Radiographic Findings

            • Imaging Recommendations

              DIFFERENTIAL DIAGNOSIS

                PATHOLOGY

                • General Features

                  • Microscopic Features

                    CLINICAL ISSUES

                    • Presentation

                      • Natural History & Prognosis

                        • Treatment

                          DIAGNOSTIC CHECKLIST

                          • Consider

                            Selected References

                            1. Wang Q et al: The safety and usefulness of neutron brachytherapy and external beam radiation in the treatment of patients with gastroesophageal junction adenocarcinoma with or without chemotherapy. Radiat Oncol. 9(1):99, 2014
                            2. Jørgensen AY et al: The effect on esophagus after different radiotherapy techniques for early stage Hodgkin's lymphoma. Acta Oncol. 52(7):1559-65, 2013
                            3. Ulaner GA et al: Identifying and distinguishing treatment effects and complications from malignancy at FDG PET/CT. Radiographics. 33(6):1817-34, 2013
                            4. Rodríguez N et al: Predictors of acute esophagitis in lung cancer patients treated with concurrent three-dimensional conformal radiotherapy and chemotherapy. Int J Radiat Oncol Biol Phys. 73(3):810-7, 2009
                            5. Tho LM et al: Oesophageal toxicity and hypofractionated concurrent chemoradiotherapy for non-small cell lung cancer. Clin Oncol (R Coll Radiol). 21(1):74, 2009
                            6. Watkins JM et al: Factors associated with severe acute esophagitis from hyperfractionated radiotherapy with concurrent chemotherapy for limited-stage small-cell lung cancer. Int J Radiat Oncol Biol Phys. 74(4):1108-13, 2009
                            7. Collazzo LA et al: Acute radiation esophagitis: radiographic findings. AJR Am J Roentgenol. 169(4):1067-70, 1997
                            8. Seeman H et al: Esophageal motor dysfunction years after radiation therapy. Dig Dis Sci. 37(2):303-6, 1992
                            9. Chowhan NM: Injurious effects of radiation on the esophagus. Am J Gastroenterol. 85(2):115-20, 1990
                            Related Anatomy
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                            Related Differential Diagnoses
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                            References
                            Tables

                            Tables

                            KEY FACTS

                            • Imaging

                              • Top Differential Diagnoses

                                • Clinical Issues

                                  TERMINOLOGY

                                  • Abbreviations

                                    • Radiation esophagitis (RE)
                                  • Definitions

                                    • Inflammation of esophageal mucosa and wall induced by curative and palliative radiotherapy (RT)

                                  IMAGING

                                  • General Features

                                    • Radiographic Findings

                                      • Imaging Recommendations

                                        DIFFERENTIAL DIAGNOSIS

                                          PATHOLOGY

                                          • General Features

                                            • Microscopic Features

                                              CLINICAL ISSUES

                                              • Presentation

                                                • Natural History & Prognosis

                                                  • Treatment

                                                    DIAGNOSTIC CHECKLIST

                                                    • Consider

                                                      Selected References

                                                      1. Wang Q et al: The safety and usefulness of neutron brachytherapy and external beam radiation in the treatment of patients with gastroesophageal junction adenocarcinoma with or without chemotherapy. Radiat Oncol. 9(1):99, 2014
                                                      2. Jørgensen AY et al: The effect on esophagus after different radiotherapy techniques for early stage Hodgkin's lymphoma. Acta Oncol. 52(7):1559-65, 2013
                                                      3. Ulaner GA et al: Identifying and distinguishing treatment effects and complications from malignancy at FDG PET/CT. Radiographics. 33(6):1817-34, 2013
                                                      4. Rodríguez N et al: Predictors of acute esophagitis in lung cancer patients treated with concurrent three-dimensional conformal radiotherapy and chemotherapy. Int J Radiat Oncol Biol Phys. 73(3):810-7, 2009
                                                      5. Tho LM et al: Oesophageal toxicity and hypofractionated concurrent chemoradiotherapy for non-small cell lung cancer. Clin Oncol (R Coll Radiol). 21(1):74, 2009
                                                      6. Watkins JM et al: Factors associated with severe acute esophagitis from hyperfractionated radiotherapy with concurrent chemotherapy for limited-stage small-cell lung cancer. Int J Radiat Oncol Biol Phys. 74(4):1108-13, 2009
                                                      7. Collazzo LA et al: Acute radiation esophagitis: radiographic findings. AJR Am J Roentgenol. 169(4):1067-70, 1997
                                                      8. Seeman H et al: Esophageal motor dysfunction years after radiation therapy. Dig Dis Sci. 37(2):303-6, 1992
                                                      9. Chowhan NM: Injurious effects of radiation on the esophagus. Am J Gastroenterol. 85(2):115-20, 1990