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Radiation Nephropathy
Benjamin Wildman-Tobriner, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Radiation nephritis (misnomer because inflammation is not present)
            • Definitions

              • Renal injury and impaired function due to direct exposure to ionizing radiation

            IMAGING

            • General Features

              • CT Findings

                • Ultrasonographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Treatment

                                    Selected References

                                    1. Edeani A et al: Radiation Nephropathy: American Society of Nephrology. Published 2016. Accessed June 2021. https://www.asn-online.org/education/distancelearning/curricula/onco/Chapter10.pdf
                                    2. Tran LK et al: Renal remodeling after abdominal radiation therapy: parenchymal and functional changes. AJR Am J Roentgenol. 203(2):W192-8, 2014
                                    3. Dawson LA et al: Radiation-associated kidney injury. Int J Radiat Oncol Biol Phys. 76(3 Suppl):S108-15, 2010
                                    4. Iyer R et al: Radiation injury: imaging findings in the chest, abdomen and pelvis after therapeutic radiation. Cancer Imaging. 6:S131-9, 2006
                                    5. Kwek JW et al: Spectrum of imaging findings in the abdomen after radiotherapy. AJR Am J Roentgenol. 187(5):1204-11, 2006
                                    6. Cohen EP et al: Radiation nephropathy. Semin Nephrol. 23(5):486-99, 2003
                                    7. Cassady JR: Clinical radiation nephropathy. Int J Radiat Oncol Biol Phys. 31(5):1249-56, 1995
                                    8. Moore L et al: Computed tomography of acute radiation nephritis. Urol Radiol. 8(2):89-91, 1986
                                    9. Andersen BL et al: Demonstration of radiation nephritis by computed tomography. Comput Radiol. 6(4):187-91, 1982
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Radiation nephritis (misnomer because inflammation is not present)
                                              • Definitions

                                                • Renal injury and impaired function due to direct exposure to ionizing radiation

                                              IMAGING

                                              • General Features

                                                • CT Findings

                                                  • Ultrasonographic Findings

                                                    • Nuclear Medicine Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Treatment

                                                                      Selected References

                                                                      1. Edeani A et al: Radiation Nephropathy: American Society of Nephrology. Published 2016. Accessed June 2021. https://www.asn-online.org/education/distancelearning/curricula/onco/Chapter10.pdf
                                                                      2. Tran LK et al: Renal remodeling after abdominal radiation therapy: parenchymal and functional changes. AJR Am J Roentgenol. 203(2):W192-8, 2014
                                                                      3. Dawson LA et al: Radiation-associated kidney injury. Int J Radiat Oncol Biol Phys. 76(3 Suppl):S108-15, 2010
                                                                      4. Iyer R et al: Radiation injury: imaging findings in the chest, abdomen and pelvis after therapeutic radiation. Cancer Imaging. 6:S131-9, 2006
                                                                      5. Kwek JW et al: Spectrum of imaging findings in the abdomen after radiotherapy. AJR Am J Roentgenol. 187(5):1204-11, 2006
                                                                      6. Cohen EP et al: Radiation nephropathy. Semin Nephrol. 23(5):486-99, 2003
                                                                      7. Cassady JR: Clinical radiation nephropathy. Int J Radiat Oncol Biol Phys. 31(5):1249-56, 1995
                                                                      8. Moore L et al: Computed tomography of acute radiation nephritis. Urol Radiol. 8(2):89-91, 1986
                                                                      9. Andersen BL et al: Demonstration of radiation nephritis by computed tomography. Comput Radiol. 6(4):187-91, 1982