link
Bookmarks
Radiation Plexopathy
Jeffrey S. Ross, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
5
1
0

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Radiation-induced plexitis (RIP), radiation-induced fibrosis (RIF)
              • Definitions

                • Post-radiation brachial plexus (BP) or lumbosacral plexus (LSP) inflammation

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Other Modality Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Chen AM et al: Dose--volume modeling of brachial plexus-associated neuropathy after radiation therapy for head-and-neck cancer: findings from a prospective screening protocol. Int J Radiat Oncol Biol Phys. 88(4):771-7, 2014
                                                2. Eblan MJ et al: Brachial plexopathy in apical non-small cell lung cancer treated with definitive radiation: dosimetric analysis and clinical implications. Int J Radiat Oncol Biol Phys. 85(1):175-81, 2013
                                                3. Pradat PF et al: Late radiation injury to peripheral nerves. Handb Clin Neurol. 115:743-58, 2013
                                                4. Chen AM et al: Brachial plexus-associated neuropathy after high-dose radiation therapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys. 84(1):165-9, 2012
                                                5. Delanian S et al: Radiation-induced neuropathy in cancer survivors. Radiother Oncol. 105(3):273-82, 2012
                                                6. Du R et al: Magnetic resonance neurography for the evaluation of peripheral nerve, brachial plexus, and nerve root disorders. J Neurosurg. Epub ahead of print, 2009
                                                7. Gosk J et al: Radiation-induced brachial plexus neuropathy - aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment. Folia Neuropathol. 45(1):26-30, 2007
                                                8. Mullins GM et al: Non-traumatic brachial plexopathies, clinical, radiological and neurophysiological findings from a tertiary centre. Clin Neurol Neurosurg. 109(8):661-6, 2007
                                                9. Teixeira MJ et al: Dorsal root entry zone lesions for treatment of pain-related to radiation-induced plexopathy. Spine (Phila Pa 1976). 32(10):E316-9, 2007
                                                10. Dahele M et al: Radiation-induced lumbo-sacral plexopathy (RILSP): an important enigma. Clin Oncol (R Coll Radiol). 18(5):427-8, 2006
                                                11. Luthra K et al: F-18 FDG PET-CT appearance of metastatic brachial plexopathy in a case of carcinoma of the breast. Clin Nucl Med. 31(7):432-4, 2006
                                                12. Bajrovic A et al: Is there a life-long risk of brachial plexopathy after radiotherapy of supraclavicular lymph nodes in breast cancer patients? Radiother Oncol. 71(3):297-301, 2004
                                                13. Hoeller U et al: Radiation-induced plexopathy and fibrosis. Is magnetic resonance imaging the adequate diagnostic tool? Strahlenther Onkol. 180(10):650-4, 2004
                                                14. Jaeckle KA: Neurological manifestations of neoplastic and radiation-induced plexopathies. Semin Neurol. 24(4):385-93, 2004
                                                15. Schierle C et al: Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. 20(2):149-52, 2004
                                                16. Fathers E et al: Radiation-induced brachial plexopathy in women treated for carcinoma of the breast. Clin Rehabil. 16(2):160-5, 2002
                                                17. Ferrante MA et al: Electrodiagnostic approach to the patient with suspected brachial plexopathy. Neurol Clin. 20(2):423-50, 2002
                                                18. Johansson S et al: Dose response and latency for radiation-induced fibrosis, edema, and neuropathy in breast cancer patients. Int J Radiat Oncol Biol Phys. 52(5):1207-19, 2002
                                                19. Lu L et al: Diagnosis and operative treatment of radiation-induced brachial plexopathy. Chin J Traumatol. 5(6):329-32, 2002
                                                20. Zingale A et al: Metastatic breast cancer delayed brachial plexopathy. A brief case report. J Neurosurg Sci. 46(3-4):147-9, 2002
                                                21. Cros D: Peripheral Neuropathy. 1st ed. Philadelphia: Lippincott Williams & Wilkins. 185-7; 2001
                                                22. Rubin DI et al: Arteritis and brachial plexus neuropathy as delayed complications of radiation therapy. Mayo Clin Proc. 76(8):849-52, 2001
                                                23. Churn M et al: Early onset of bilateral brachial plexopathy during mantle radiotherapy for Hodgkin's disease. Clin Oncol (R Coll Radiol). 12(5):289-91, 2000
                                                24. Johansson S et al: Brachial plexopathy after postoperative radiotherapy of breast cancer patients--a long-term follow-up. Acta Oncol. 39(3):373-82, 2000
                                                25. Johansson S et al: Timescale of evolution of late radiation injury after postoperative radiotherapy of breast cancer patients. Int J Radiat Oncol Biol Phys. 48(3):745-50, 2000
                                                26. Qayyum A et al: Symptomatic brachial plexopathy following treatment for breast cancer: utility of MR imaging with surface-coil techniques. Radiology. 214(3):837-42, 2000
                                                27. Wittenberg KH et al: MR imaging of nontraumatic brachial plexopathies: frequency and spectrum of findings. Radiographics. 20(4):1023-32, 2000
                                                28. Abu-Rustum NR et al: Acute lower extremity paralysis following radiation therapy for cervical cancer. Gynecol Oncol. 75(1):152-4, 1999
                                                29. Wadd NJ et al: Brachial plexus neuropathy following mantle radiotherapy. Clin Oncol (R Coll Radiol). 10(6):399-400, 1998
                                                30. Wouter van Es H et al: Radiation-induced brachial plexopathy: MR imaging. Skeletal Radiol. 26(5):284-8, 1997
                                                31. Bowen BC et al: Radiation-induced brachial plexopathy: MR and clinical findings. AJNR Am J Neuroradiol. 17(10):1932-6, 1996
                                                32. Iyer RB et al: MR imaging of the treated brachial plexus. AJR Am J Roentgenol. 167(1):225-9, 1996
                                                Related Anatomy
                                                Loading...
                                                Related Differential Diagnoses
                                                Loading...
                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Synonyms

                                                              • Radiation-induced plexitis (RIP), radiation-induced fibrosis (RIF)
                                                            • Definitions

                                                              • Post-radiation brachial plexus (BP) or lumbosacral plexus (LSP) inflammation

                                                            IMAGING

                                                            • General Features

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Other Modality Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Staging, Grading, & Classification

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Chen AM et al: Dose--volume modeling of brachial plexus-associated neuropathy after radiation therapy for head-and-neck cancer: findings from a prospective screening protocol. Int J Radiat Oncol Biol Phys. 88(4):771-7, 2014
                                                                                              2. Eblan MJ et al: Brachial plexopathy in apical non-small cell lung cancer treated with definitive radiation: dosimetric analysis and clinical implications. Int J Radiat Oncol Biol Phys. 85(1):175-81, 2013
                                                                                              3. Pradat PF et al: Late radiation injury to peripheral nerves. Handb Clin Neurol. 115:743-58, 2013
                                                                                              4. Chen AM et al: Brachial plexus-associated neuropathy after high-dose radiation therapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys. 84(1):165-9, 2012
                                                                                              5. Delanian S et al: Radiation-induced neuropathy in cancer survivors. Radiother Oncol. 105(3):273-82, 2012
                                                                                              6. Du R et al: Magnetic resonance neurography for the evaluation of peripheral nerve, brachial plexus, and nerve root disorders. J Neurosurg. Epub ahead of print, 2009
                                                                                              7. Gosk J et al: Radiation-induced brachial plexus neuropathy - aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment. Folia Neuropathol. 45(1):26-30, 2007
                                                                                              8. Mullins GM et al: Non-traumatic brachial plexopathies, clinical, radiological and neurophysiological findings from a tertiary centre. Clin Neurol Neurosurg. 109(8):661-6, 2007
                                                                                              9. Teixeira MJ et al: Dorsal root entry zone lesions for treatment of pain-related to radiation-induced plexopathy. Spine (Phila Pa 1976). 32(10):E316-9, 2007
                                                                                              10. Dahele M et al: Radiation-induced lumbo-sacral plexopathy (RILSP): an important enigma. Clin Oncol (R Coll Radiol). 18(5):427-8, 2006
                                                                                              11. Luthra K et al: F-18 FDG PET-CT appearance of metastatic brachial plexopathy in a case of carcinoma of the breast. Clin Nucl Med. 31(7):432-4, 2006
                                                                                              12. Bajrovic A et al: Is there a life-long risk of brachial plexopathy after radiotherapy of supraclavicular lymph nodes in breast cancer patients? Radiother Oncol. 71(3):297-301, 2004
                                                                                              13. Hoeller U et al: Radiation-induced plexopathy and fibrosis. Is magnetic resonance imaging the adequate diagnostic tool? Strahlenther Onkol. 180(10):650-4, 2004
                                                                                              14. Jaeckle KA: Neurological manifestations of neoplastic and radiation-induced plexopathies. Semin Neurol. 24(4):385-93, 2004
                                                                                              15. Schierle C et al: Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. 20(2):149-52, 2004
                                                                                              16. Fathers E et al: Radiation-induced brachial plexopathy in women treated for carcinoma of the breast. Clin Rehabil. 16(2):160-5, 2002
                                                                                              17. Ferrante MA et al: Electrodiagnostic approach to the patient with suspected brachial plexopathy. Neurol Clin. 20(2):423-50, 2002
                                                                                              18. Johansson S et al: Dose response and latency for radiation-induced fibrosis, edema, and neuropathy in breast cancer patients. Int J Radiat Oncol Biol Phys. 52(5):1207-19, 2002
                                                                                              19. Lu L et al: Diagnosis and operative treatment of radiation-induced brachial plexopathy. Chin J Traumatol. 5(6):329-32, 2002
                                                                                              20. Zingale A et al: Metastatic breast cancer delayed brachial plexopathy. A brief case report. J Neurosurg Sci. 46(3-4):147-9, 2002
                                                                                              21. Cros D: Peripheral Neuropathy. 1st ed. Philadelphia: Lippincott Williams & Wilkins. 185-7; 2001
                                                                                              22. Rubin DI et al: Arteritis and brachial plexus neuropathy as delayed complications of radiation therapy. Mayo Clin Proc. 76(8):849-52, 2001
                                                                                              23. Churn M et al: Early onset of bilateral brachial plexopathy during mantle radiotherapy for Hodgkin's disease. Clin Oncol (R Coll Radiol). 12(5):289-91, 2000
                                                                                              24. Johansson S et al: Brachial plexopathy after postoperative radiotherapy of breast cancer patients--a long-term follow-up. Acta Oncol. 39(3):373-82, 2000
                                                                                              25. Johansson S et al: Timescale of evolution of late radiation injury after postoperative radiotherapy of breast cancer patients. Int J Radiat Oncol Biol Phys. 48(3):745-50, 2000
                                                                                              26. Qayyum A et al: Symptomatic brachial plexopathy following treatment for breast cancer: utility of MR imaging with surface-coil techniques. Radiology. 214(3):837-42, 2000
                                                                                              27. Wittenberg KH et al: MR imaging of nontraumatic brachial plexopathies: frequency and spectrum of findings. Radiographics. 20(4):1023-32, 2000
                                                                                              28. Abu-Rustum NR et al: Acute lower extremity paralysis following radiation therapy for cervical cancer. Gynecol Oncol. 75(1):152-4, 1999
                                                                                              29. Wadd NJ et al: Brachial plexus neuropathy following mantle radiotherapy. Clin Oncol (R Coll Radiol). 10(6):399-400, 1998
                                                                                              30. Wouter van Es H et al: Radiation-induced brachial plexopathy: MR imaging. Skeletal Radiol. 26(5):284-8, 1997
                                                                                              31. Bowen BC et al: Radiation-induced brachial plexopathy: MR and clinical findings. AJNR Am J Neuroradiol. 17(10):1932-6, 1996
                                                                                              32. Iyer RB et al: MR imaging of the treated brachial plexus. AJR Am J Roentgenol. 167(1):225-9, 1996