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Reactive Adenopathy of Retropharyngeal Space
Bronwyn E. Hamilton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Retropharyngeal space (RPS) nodes
              • Synonyms

                • Reactive lymphoid hyperplasia, nodal hyperplasia; lateral RPS nodes: Nodes of Rouvière
              • Definitions

                • Benign enlargement of nodes in response to antigen

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            Selected References

                                            1. Aiken AH et al: Approach to masses in head and neck spaces. In: Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging. [Internet]. Hodler J et al, editors. Cham: Springer, 2020
                                            2. Ando T et al: Diagnostic ability of contrast-enhanced computed tomography for metastatic cervical nodes in head and neck squamous cell carcinomas: significance of additional coronal reconstruction images. Pol J Radiol. 85:e1-7, 2020
                                            3. Zhou X et al: FDG PET/CT used in identifying adult-onset Still's disease in connective tissue diseases. Clin Rheumatol. 39(9):2735-42, 2020
                                            4. Isidori C et al: A case of incomplete and atypical kawasaki disease presenting with retropharyngeal involvement. Int J Environ Res Public Health. 16(18), 2019
                                            5. Vu TH et al: Diagnostic accuracy and scope of intraoperative transoral ultrasound and transoral ultrasound-guided fine-needle aspiration of retropharyngeal masses. AJNR Am J Neuroradiol. 40(11):1960-4, 2019
                                            6. Costa NS et al: Retropharyngeal lymph nodes in children: a common imaging finding and potential source of misinterpretation. AJR Am J Roentgenol. 196(4):W433-7, 2011
                                            7. *Holzapfel K et al: Value of diffusion-weighted MR imaging in the differentiation between benign and malignant cervical lymph nodes. Eur J Radiol. 72(3):381-7, 2008
                                            8. Chong VF et al: Radiology of the retropharyngeal space. Clin Radiol. 55(10):740-8, 2000
                                            9. Sakai F et al: Computed tomography of neck lymph nodes involved with malignant lymphoma: comparison with ultrasound. Radiat Med. 9(6):203-8, 1991
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Retropharyngeal space (RPS) nodes
                                                        • Synonyms

                                                          • Reactive lymphoid hyperplasia, nodal hyperplasia; lateral RPS nodes: Nodes of Rouvière
                                                        • Definitions

                                                          • Benign enlargement of nodes in response to antigen

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Gross Pathologic & Surgical Features

                                                                          • Microscopic Features

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      Selected References

                                                                                      1. Aiken AH et al: Approach to masses in head and neck spaces. In: Diseases of the Brain, Head and Neck, Spine 2020–2023: Diagnostic Imaging. [Internet]. Hodler J et al, editors. Cham: Springer, 2020
                                                                                      2. Ando T et al: Diagnostic ability of contrast-enhanced computed tomography for metastatic cervical nodes in head and neck squamous cell carcinomas: significance of additional coronal reconstruction images. Pol J Radiol. 85:e1-7, 2020
                                                                                      3. Zhou X et al: FDG PET/CT used in identifying adult-onset Still's disease in connective tissue diseases. Clin Rheumatol. 39(9):2735-42, 2020
                                                                                      4. Isidori C et al: A case of incomplete and atypical kawasaki disease presenting with retropharyngeal involvement. Int J Environ Res Public Health. 16(18), 2019
                                                                                      5. Vu TH et al: Diagnostic accuracy and scope of intraoperative transoral ultrasound and transoral ultrasound-guided fine-needle aspiration of retropharyngeal masses. AJNR Am J Neuroradiol. 40(11):1960-4, 2019
                                                                                      6. Costa NS et al: Retropharyngeal lymph nodes in children: a common imaging finding and potential source of misinterpretation. AJR Am J Roentgenol. 196(4):W433-7, 2011
                                                                                      7. *Holzapfel K et al: Value of diffusion-weighted MR imaging in the differentiation between benign and malignant cervical lymph nodes. Eur J Radiol. 72(3):381-7, 2008
                                                                                      8. Chong VF et al: Radiology of the retropharyngeal space. Clin Radiol. 55(10):740-8, 2000
                                                                                      9. Sakai F et al: Computed tomography of neck lymph nodes involved with malignant lymphoma: comparison with ultrasound. Radiat Med. 9(6):203-8, 1991