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Reactive Lymph Nodes
Christine M. Glastonbury, MBBS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Reactive adenopathy, reactive lymphoid hyperplasia, nodal hyperplasia
            • Definitions

              • Benign, reversible enlargement of nodes in response to antigen stimulus
                • Nodal involvement may be acute or chronic, localized or generalized
              • "Reactive" implies benign etiology

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. McCormick ME et al: Socioeconomic implications of pediatric cervical methicillin-resistant Staphylococcus aureus infections. JAMA Otolaryngol Head Neck Surg. 139(2):124-8, 2013
                                            2. Duggal P et al: The increased risk of community-acquired methicillin-resistant Staphylococcus aureus neck abscesses in young children. Laryngoscope. 121(1):51-5, 2011
                                            3. Naseri I et al: Nationwide trends in pediatric Staphylococcus aureus head and neck infections. Arch Otolaryngol Head Neck Surg. 135(1):14-6, 2009
                                            4. Leung AK et al: Childhood cervical lymphadenopathy. J Pediatr Health Care. 18(1):3-7, 2004
                                            5. Papakonstantinou O et al: High-resolution and color Doppler ultrasonography of cervical lymphadenopathy in children. Acta Radiol. 42(5):470-6, 2001
                                            6. Ahuja A et al: Grey-scale sonography in assessment of cervical lymphadenopathy: review of sonographic appearances and features that may help a beginner. Br J Oral Maxillofac Surg. 38(5):451-9, 2000
                                            7. Robson CD et al: Nontuberculous mycobacterial infection of the head and neck in immunocompetent children: CT and MR findings. AJNR Am J Neuroradiol. 20(10):1829-35, 1999
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Reactive adenopathy, reactive lymphoid hyperplasia, nodal hyperplasia
                                                      • Definitions

                                                        • Benign, reversible enlargement of nodes in response to antigen stimulus
                                                          • Nodal involvement may be acute or chronic, localized or generalized
                                                        • "Reactive" implies benign etiology

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. McCormick ME et al: Socioeconomic implications of pediatric cervical methicillin-resistant Staphylococcus aureus infections. JAMA Otolaryngol Head Neck Surg. 139(2):124-8, 2013
                                                                                      2. Duggal P et al: The increased risk of community-acquired methicillin-resistant Staphylococcus aureus neck abscesses in young children. Laryngoscope. 121(1):51-5, 2011
                                                                                      3. Naseri I et al: Nationwide trends in pediatric Staphylococcus aureus head and neck infections. Arch Otolaryngol Head Neck Surg. 135(1):14-6, 2009
                                                                                      4. Leung AK et al: Childhood cervical lymphadenopathy. J Pediatr Health Care. 18(1):3-7, 2004
                                                                                      5. Papakonstantinou O et al: High-resolution and color Doppler ultrasonography of cervical lymphadenopathy in children. Acta Radiol. 42(5):470-6, 2001
                                                                                      6. Ahuja A et al: Grey-scale sonography in assessment of cervical lymphadenopathy: review of sonographic appearances and features that may help a beginner. Br J Oral Maxillofac Surg. 38(5):451-9, 2000
                                                                                      7. Robson CD et al: Nontuberculous mycobacterial infection of the head and neck in immunocompetent children: CT and MR findings. AJNR Am J Neuroradiol. 20(10):1829-35, 1999