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Reflux Esophagitis
Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Inflammation of esophageal mucosa due to gastroesophageal (GE) reflux

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Li B et al: Reducing the gastroesophageal reflux with lip-type reinforcement technique during intrathoracic esophagogastrostomy. Hepatogastroenterology. 60(127):1541-6, 2013
                                          2. Pelechas E et al: Gastroesophageal reflux disease: epidemiological data, symptomatology and risk factors. Rev Med Chir Soc Med Nat Iasi. 117(1):183-8, 2013
                                          3. Zagari RM et al: Gastro-oesophageal reflux symptoms, oesophagitis and Barrett's oesophagus in the general population: the Loiano-Monghidoro study. Gut. 57(10):1354-9, 2008
                                          4. Moayyedi P et al: Gastro-oesophageal reflux disease. Lancet. 367(9528):2086-100, 2006
                                          5. Vakil N et al: The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 101(8):1900-20; quiz 1943, 2006
                                          6. Levine MS et al: Diseases of the esophagus: diagnosis with esophagography. Radiology. 237(2):414-27, 2005
                                          7. Dibble C et al: Detection of reflux esophagitis on double-contrast esophagrams and endoscopy using the histologic findings as the gold standard. Abdom Imaging. 29(4):421-5, 2004
                                          8. Hu C et al: Solitary ulcers in reflux esophagitis: radiographic findings. Abdom Imaging. 22(1):5-7, 1997
                                          9. Levine MS: Reflux esophagitis and Barrett's esophagus. Semin Roentgenol. 29(4):332-40, 1994
                                          10. Thompson JK et al: Detection of gastroesophageal reflux: value of barium studies compared with 24-hr pH monitoring. AJR Am J Roentgenol. 162(3):621-6, 1994
                                          11. Levine MS: Radiology of esophagitis: a pattern approach. Radiology. 179(1):1-7, 1991
                                          12. Levine MS et al: Update on esophageal radiology. AJR Am J Roentgenol. 155(5):933-41, 1990
                                          13. Mann NS et al: Barrett's esophagus in patients with symptomatic reflux esophagitis. Am J Gastroenterol. 84(12):1494-6, 1989
                                          14. Levine MS et al: Pseudomembranes in reflux esophagitis. Radiology. 159(1):43-5, 1986
                                          15. Levine MS et al: Fixed transverse folds in the esophagus: a sign of reflux esophagitis. AJR Am J Roentgenol. 143(2):275-8, 1984
                                          16. Creteur V et al: The role of single and double-contrast radiography in the diagnosis of reflux esophagitis. Radiology. 147(1):71-5, 1983
                                          17. Graziani L et al: Reflux esophagitis: radiologic-endoscopic correlation in 39 symptomatic cases. Gastrointest Radiol. 8(1):1-6, 1983
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Inflammation of esophageal mucosa due to gastroesophageal (GE) reflux

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Li B et al: Reducing the gastroesophageal reflux with lip-type reinforcement technique during intrathoracic esophagogastrostomy. Hepatogastroenterology. 60(127):1541-6, 2013
                                                                                  2. Pelechas E et al: Gastroesophageal reflux disease: epidemiological data, symptomatology and risk factors. Rev Med Chir Soc Med Nat Iasi. 117(1):183-8, 2013
                                                                                  3. Zagari RM et al: Gastro-oesophageal reflux symptoms, oesophagitis and Barrett's oesophagus in the general population: the Loiano-Monghidoro study. Gut. 57(10):1354-9, 2008
                                                                                  4. Moayyedi P et al: Gastro-oesophageal reflux disease. Lancet. 367(9528):2086-100, 2006
                                                                                  5. Vakil N et al: The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 101(8):1900-20; quiz 1943, 2006
                                                                                  6. Levine MS et al: Diseases of the esophagus: diagnosis with esophagography. Radiology. 237(2):414-27, 2005
                                                                                  7. Dibble C et al: Detection of reflux esophagitis on double-contrast esophagrams and endoscopy using the histologic findings as the gold standard. Abdom Imaging. 29(4):421-5, 2004
                                                                                  8. Hu C et al: Solitary ulcers in reflux esophagitis: radiographic findings. Abdom Imaging. 22(1):5-7, 1997
                                                                                  9. Levine MS: Reflux esophagitis and Barrett's esophagus. Semin Roentgenol. 29(4):332-40, 1994
                                                                                  10. Thompson JK et al: Detection of gastroesophageal reflux: value of barium studies compared with 24-hr pH monitoring. AJR Am J Roentgenol. 162(3):621-6, 1994
                                                                                  11. Levine MS: Radiology of esophagitis: a pattern approach. Radiology. 179(1):1-7, 1991
                                                                                  12. Levine MS et al: Update on esophageal radiology. AJR Am J Roentgenol. 155(5):933-41, 1990
                                                                                  13. Mann NS et al: Barrett's esophagus in patients with symptomatic reflux esophagitis. Am J Gastroenterol. 84(12):1494-6, 1989
                                                                                  14. Levine MS et al: Pseudomembranes in reflux esophagitis. Radiology. 159(1):43-5, 1986
                                                                                  15. Levine MS et al: Fixed transverse folds in the esophagus: a sign of reflux esophagitis. AJR Am J Roentgenol. 143(2):275-8, 1984
                                                                                  16. Creteur V et al: The role of single and double-contrast radiography in the diagnosis of reflux esophagitis. Radiology. 147(1):71-5, 1983
                                                                                  17. Graziani L et al: Reflux esophagitis: radiologic-endoscopic correlation in 39 symptomatic cases. Gastrointest Radiol. 8(1):1-6, 1983