Distribution of calcifications (Ca⁺⁺) over large (> 2 cm) span, not in expected distribution of duct
Can involve solitary or multiple regions
May involve most of 1 quadrant or > 1 quadrant
Use "grouped" when ≤ 2 cm span and not in distribution of duct(s)
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
Image-Guided Biopsy
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Kaltenbach B et al: A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies. Eur J Radiol. 86:221-226, 2017
Raj SD et al: Stereotactic biopsy of segmental breast calcifications: Is sampling of anterior and posterior components necessary? Acad Radiol. 23(6):682-6, 2016
Chang Sen LQ et al: Core breast biopsies showing lobular carcinoma in situ should be excised and surveillance is reasonable for atypical lobular hyperplasia. AJR Am J Roentgenol. 207(5):1132-1145, 2016
Kim SY et al: Evaluation of malignancy risk stratification of microcalcifications detected on mammography: a study based on the 5th edition of BI-RADS. Ann Surg Oncol. 22(9):2895-901, 2015
Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston: American College of Radiology, 2013
Bent CK et al: The positive predictive value of BI-RADS microcalcification descriptors and final assessment categories. AJR Am J Roentgenol. 194(5):1378-83, 2010
Burnside ES et al: Use of microcalcification descriptors in BI-RADS 4th edition to stratify risk of malignancy. Radiology. 242(2):388-95, 2007
Soo MS et al: Sonographic detection and sonographically guided biopsy of breast microcalcifications. AJR Am J Roentgenol. 180(4):941-8, 2003
Liberman L et al: Bracketing wires for preoperative breast needle localization. AJR Am J Roentgenol. 177(3):565-72, 2001
Moon WK et al: US of mammographically detected clustered microcalcifications. Radiology. 217(3):849-54, 2000
Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
Gluck BS et al: Microcalcifications on postoperative mammograms as an indicator of adequacy of tumor excision. Radiology. 188(2):469-72, 1993
Holland R et al: Extent, distribution, and mammographic/histological correlations of breast ductal carcinoma in situ. Lancet. 335(8688):519-22, 1990
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Diagnostic Checklist
TERMINOLOGY
Definitions
Distribution of calcifications (Ca⁺⁺) over large (> 2 cm) span, not in expected distribution of duct
Can involve solitary or multiple regions
May involve most of 1 quadrant or > 1 quadrant
Use "grouped" when ≤ 2 cm span and not in distribution of duct(s)
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
Image-Guided Biopsy
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Kaltenbach B et al: A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies. Eur J Radiol. 86:221-226, 2017
Raj SD et al: Stereotactic biopsy of segmental breast calcifications: Is sampling of anterior and posterior components necessary? Acad Radiol. 23(6):682-6, 2016
Chang Sen LQ et al: Core breast biopsies showing lobular carcinoma in situ should be excised and surveillance is reasonable for atypical lobular hyperplasia. AJR Am J Roentgenol. 207(5):1132-1145, 2016
Kim SY et al: Evaluation of malignancy risk stratification of microcalcifications detected on mammography: a study based on the 5th edition of BI-RADS. Ann Surg Oncol. 22(9):2895-901, 2015
Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston: American College of Radiology, 2013
Bent CK et al: The positive predictive value of BI-RADS microcalcification descriptors and final assessment categories. AJR Am J Roentgenol. 194(5):1378-83, 2010
Burnside ES et al: Use of microcalcification descriptors in BI-RADS 4th edition to stratify risk of malignancy. Radiology. 242(2):388-95, 2007
Soo MS et al: Sonographic detection and sonographically guided biopsy of breast microcalcifications. AJR Am J Roentgenol. 180(4):941-8, 2003
Liberman L et al: Bracketing wires for preoperative breast needle localization. AJR Am J Roentgenol. 177(3):565-72, 2001
Moon WK et al: US of mammographically detected clustered microcalcifications. Radiology. 217(3):849-54, 2000
Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
Gluck BS et al: Microcalcifications on postoperative mammograms as an indicator of adequacy of tumor excision. Radiology. 188(2):469-72, 1993
Holland R et al: Extent, distribution, and mammographic/histological correlations of breast ductal carcinoma in situ. Lancet. 335(8688):519-22, 1990
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