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Renal Lymphoma
Jade Wong-You-Cheong, MBChB, MRCP, FRCR, FSRU, FSAR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Lymphoma: Malignant tumor of lymphocytes
                • Primary: Involvement of kidneys without evidence of other organ or nodal involvement
                  • Extremely rare; < 0.7% of extranodal lymphoma
                • Secondary: Dissemination of extrarenal lymphoma by hematogenous spread (90%) or direct extension via retroperitoneal lymphatic channels
                  • Non-Hodgkin lymphoma > > Hodgkin disease

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  • CT Findings

                    • MR Findings

                      • Image-Guided Biopsy

                        • Nuclear Medicine Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Zheng Y et al: IgG4-related disease in the abdomen and pelvis: atypical findings, pitfalls, and mimics. Abdom Radiol (NY). 45(8):2485-99, 2020
                                              2. Weber J et al: Imaging features of immune-mediated genitourinary disease. Abdom Radiol (NY). 44(6):2217-32, 2019
                                              3. Kazmierski B et al: Applications of contrast-enhanced ultrasound in the kidney. Abdom Radiol (NY). 43(4):880-98, 2018
                                              4. Ballard DH et al: CT imaging spectrum of infiltrative renal diseases. Abdom Radiol (NY). 42(11):2700-9, 2017
                                              5. Hedgire SS et al: Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis. Abdom Radiol (NY). 42(4):1096-112, 2017
                                              6. Ganeshan D et al: Imaging of primary and secondary renal lymphoma. AJR Am J Roentgenol. 201(5):W712-9, 2013
                                              7. Kostakoglu L et al: State-of-the-art research on "lymphomas: role of molecular imaging for staging, prognostic evaluation, and treatment response". Front Oncol. 3:212, 2013
                                              8. Bach AG et al: Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases. Acta Radiol. 53(3):343-8, 2012
                                              9. Ye XH et al: 18F-FDG PET/CT evaluation of lymphoma with renal involvement: comparison with renal carcinoma. South Med J. 103(7):642-9, 2010
                                              10. El-Sharkawy MS et al: Renal involvement in lymphoma: prevalence and various patterns of involvement on abdominal CT. Int Urol Nephrol. 39(3):929-33, 2007
                                              11. Sheth S et al: Imaging of renal lymphoma: patterns of disease with pathologic correlation. Radiographics. 26(4):1151-68, 2006
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Definitions

                                                            • Lymphoma: Malignant tumor of lymphocytes
                                                            • Primary: Involvement of kidneys without evidence of other organ or nodal involvement
                                                              • Extremely rare; < 0.7% of extranodal lymphoma
                                                            • Secondary: Dissemination of extrarenal lymphoma by hematogenous spread (90%) or direct extension via retroperitoneal lymphatic channels
                                                              • Non-Hodgkin lymphoma > > Hodgkin disease

                                                          IMAGING

                                                          • General Features

                                                            • Ultrasonographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Image-Guided Biopsy

                                                                    • Nuclear Medicine Findings

                                                                      • Imaging Recommendations

                                                                        DIFFERENTIAL DIAGNOSIS

                                                                          PATHOLOGY

                                                                          • General Features

                                                                            • Gross Pathologic & Surgical Features

                                                                              CLINICAL ISSUES

                                                                              • Presentation

                                                                                • Demographics

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Zheng Y et al: IgG4-related disease in the abdomen and pelvis: atypical findings, pitfalls, and mimics. Abdom Radiol (NY). 45(8):2485-99, 2020
                                                                                          2. Weber J et al: Imaging features of immune-mediated genitourinary disease. Abdom Radiol (NY). 44(6):2217-32, 2019
                                                                                          3. Kazmierski B et al: Applications of contrast-enhanced ultrasound in the kidney. Abdom Radiol (NY). 43(4):880-98, 2018
                                                                                          4. Ballard DH et al: CT imaging spectrum of infiltrative renal diseases. Abdom Radiol (NY). 42(11):2700-9, 2017
                                                                                          5. Hedgire SS et al: Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis. Abdom Radiol (NY). 42(4):1096-112, 2017
                                                                                          6. Ganeshan D et al: Imaging of primary and secondary renal lymphoma. AJR Am J Roentgenol. 201(5):W712-9, 2013
                                                                                          7. Kostakoglu L et al: State-of-the-art research on "lymphomas: role of molecular imaging for staging, prognostic evaluation, and treatment response". Front Oncol. 3:212, 2013
                                                                                          8. Bach AG et al: Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases. Acta Radiol. 53(3):343-8, 2012
                                                                                          9. Ye XH et al: 18F-FDG PET/CT evaluation of lymphoma with renal involvement: comparison with renal carcinoma. South Med J. 103(7):642-9, 2010
                                                                                          10. El-Sharkawy MS et al: Renal involvement in lymphoma: prevalence and various patterns of involvement on abdominal CT. Int Urol Nephrol. 39(3):929-33, 2007
                                                                                          11. Sheth S et al: Imaging of renal lymphoma: patterns of disease with pathologic correlation. Radiographics. 26(4):1151-68, 2006