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Renal Lymphoma
Hammed Ninalowo, MD; Jade Wong-You-Cheong, MBChB, MRCP, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Primary renal lymphoma (PRL); secondary renal lymphoma (SRL)
              • Definitions

                • Lymphoma: Malignant tumor of lymphocytes
                • Primary: Involvement of kidneys without evidence of other organ or nodal involvement
                  • Extremely rare; < 1% of extranodal lymphoma
                • Secondary: Dissemination of extrarenal lymphoma by hematogenous spread (90%) or direct extension via retroperitoneal lymphatic channels
                  • Non-Hodgkin lymphoma >> Hodgkin disease

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  • CT Findings

                    • MR Findings

                      • Image-Guided Biopsy

                        • Nuclear Medicine Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                Selected References

                                                1. Ganeshan D et al: Imaging of primary and secondary renal lymphoma. AJR Am J Roentgenol. 201(5):W712-9, 2013
                                                2. Kostakoglu L et al: State-of-the-Art Research on "Lymphomas: Role of Molecular Imaging for Staging, Prognostic Evaluation, and Treatment Response". Front Oncol. 3:212, 2013
                                                3. Bach AG et al: Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases. Acta Radiol. 53(3):343-8, 2012
                                                4. Ye XH et al: 18F-FDG PET/CT evaluation of lymphoma with renal involvement: comparison with renal carcinoma. South Med J. 103(7):642-9, 2010
                                                5. El-Sharkawy MS et al: Renal involvement in lymphoma: prevalence and various patterns of involvement on abdominal CT. Int Urol Nephrol. 39(3):929-33, 2007
                                                6. Sheth S et al: Imaging of renal lymphoma: patterns of disease with pathologic correlation. Radiographics. 26(4):1151-68, 2006
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Primary renal lymphoma (PRL); secondary renal lymphoma (SRL)
                                                            • Definitions

                                                              • Lymphoma: Malignant tumor of lymphocytes
                                                              • Primary: Involvement of kidneys without evidence of other organ or nodal involvement
                                                                • Extremely rare; < 1% of extranodal lymphoma
                                                              • Secondary: Dissemination of extrarenal lymphoma by hematogenous spread (90%) or direct extension via retroperitoneal lymphatic channels
                                                                • Non-Hodgkin lymphoma >> Hodgkin disease

                                                            IMAGING

                                                            • General Features

                                                              • Ultrasonographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Image-Guided Biopsy

                                                                      • Nuclear Medicine Findings

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Gross Pathologic & Surgical Features

                                                                                • Microscopic Features

                                                                                  CLINICAL ISSUES

                                                                                  • Presentation

                                                                                    • Demographics

                                                                                      • Natural History & Prognosis

                                                                                        • Treatment

                                                                                          DIAGNOSTIC CHECKLIST

                                                                                          • Consider

                                                                                            • Image Interpretation Pearls

                                                                                              Selected References

                                                                                              1. Ganeshan D et al: Imaging of primary and secondary renal lymphoma. AJR Am J Roentgenol. 201(5):W712-9, 2013
                                                                                              2. Kostakoglu L et al: State-of-the-Art Research on "Lymphomas: Role of Molecular Imaging for Staging, Prognostic Evaluation, and Treatment Response". Front Oncol. 3:212, 2013
                                                                                              3. Bach AG et al: Prevalence and patterns of renal involvement in imaging of malignant lymphoproliferative diseases. Acta Radiol. 53(3):343-8, 2012
                                                                                              4. Ye XH et al: 18F-FDG PET/CT evaluation of lymphoma with renal involvement: comparison with renal carcinoma. South Med J. 103(7):642-9, 2010
                                                                                              5. El-Sharkawy MS et al: Renal involvement in lymphoma: prevalence and various patterns of involvement on abdominal CT. Int Urol Nephrol. 39(3):929-33, 2007
                                                                                              6. Sheth S et al: Imaging of renal lymphoma: patterns of disease with pathologic correlation. Radiographics. 26(4):1151-68, 2006