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Renal Osteodystrophy
Cheryl A. Petersilge, MD, MBA; B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          TERMINOLOGY

          • Definitions

            • Bone & soft tissue disease resulting from end-stage renal disease (ESRD)
              • Combination of 2° hyperparathyroidism (HPTH), osteomalacia, osteoporosis, neoostosis

          IMAGING

          • General Features

            • Imaging Recommendations

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Other Modality Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Microscopic Features

                              • Laboratory Analysis

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    Selected References

                                    1. Babayev R et al: Bone disorders in chronic kidney disease: an update in diagnosis and management. Semin Dial. 28(6):645-53, 2015
                                    2. Degrassi F et al: Imaging of haemodialysis: renal and extrarenal findings. Insights Imaging. 6(3):309-21, 2015
                                    3. Kazama JJ et al: Chronic kidney disease and bone metabolism. J Bone Miner Metab. 33(3):245-52, 2015
                                    4. Abdel Razek AA: Computed tomography and magnetic resonance imaging of maxillofacial lesions in renal osteodystrophy. J Craniofac Surg. 25(4):1354-7, 2014
                                    5. Rajapakse CS et al: Micro-MR imaging-based computational biomechanics demonstrates reduction in cortical and trabecular bone strength after renal transplantation. Radiology. 262(3):912-20, 2012
                                    6. Sundaram M. Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
                                    7. Kelly A et al: Musculoskeletal pain in dialysis-related amyloidosis. Can J Surg. 50(4):305-6, 2007
                                    8. Slavotinek JP et al: Shoulder appearances at MR imaging in long-term dialysis recipients. Radiology. 217(2):539-43, 2000
                                    9. Murphey MD et al: Musculoskeletal manifestations of chronic renal insufficiency. Radiographics. 13(2):357-79, 1993
                                    10. Kurer MH et al: Musculoskeletal manifestations of amyloidosis. A review of 83 patients on haemodialysis for at least 10 years. J Bone Joint Surg Br. 73(2):271-6, 1991
                                    11. Jensen PS et al: Early radiographic manifestations of secondary hyperparathyroidism associated with chronic renal disease. Radiology. 125(3):645-52, 1977
                                    12. Greenfield GB: Roentgen appearance of bone and soft tissue changes in chronic renal disease. Am J Roentgenol Radium Ther Nucl Med. 116(4):749-57, 1972
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            TERMINOLOGY

                                            • Definitions

                                              • Bone & soft tissue disease resulting from end-stage renal disease (ESRD)
                                                • Combination of 2° hyperparathyroidism (HPTH), osteomalacia, osteoporosis, neoostosis

                                            IMAGING

                                            • General Features

                                              • Imaging Recommendations

                                                • Radiographic Findings

                                                  • CT Findings

                                                    • MR Findings

                                                      • Nuclear Medicine Findings

                                                        • Other Modality Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Microscopic Features

                                                                • Laboratory Analysis

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      Selected References

                                                                      1. Babayev R et al: Bone disorders in chronic kidney disease: an update in diagnosis and management. Semin Dial. 28(6):645-53, 2015
                                                                      2. Degrassi F et al: Imaging of haemodialysis: renal and extrarenal findings. Insights Imaging. 6(3):309-21, 2015
                                                                      3. Kazama JJ et al: Chronic kidney disease and bone metabolism. J Bone Miner Metab. 33(3):245-52, 2015
                                                                      4. Abdel Razek AA: Computed tomography and magnetic resonance imaging of maxillofacial lesions in renal osteodystrophy. J Craniofac Surg. 25(4):1354-7, 2014
                                                                      5. Rajapakse CS et al: Micro-MR imaging-based computational biomechanics demonstrates reduction in cortical and trabecular bone strength after renal transplantation. Radiology. 262(3):912-20, 2012
                                                                      6. Sundaram M. Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
                                                                      7. Kelly A et al: Musculoskeletal pain in dialysis-related amyloidosis. Can J Surg. 50(4):305-6, 2007
                                                                      8. Slavotinek JP et al: Shoulder appearances at MR imaging in long-term dialysis recipients. Radiology. 217(2):539-43, 2000
                                                                      9. Murphey MD et al: Musculoskeletal manifestations of chronic renal insufficiency. Radiographics. 13(2):357-79, 1993
                                                                      10. Kurer MH et al: Musculoskeletal manifestations of amyloidosis. A review of 83 patients on haemodialysis for at least 10 years. J Bone Joint Surg Br. 73(2):271-6, 1991
                                                                      11. Jensen PS et al: Early radiographic manifestations of secondary hyperparathyroidism associated with chronic renal disease. Radiology. 125(3):645-52, 1977
                                                                      12. Greenfield GB: Roentgen appearance of bone and soft tissue changes in chronic renal disease. Am J Roentgenol Radium Ther Nucl Med. 116(4):749-57, 1972