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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Renal osteodystrophy (OD)
Definitions
- Chronic kidney disease-mineral and bone disorder (CKD-MBD): Constellation of abnormalities seen in progressive kidney disease, including metabolic abnormalities, disturbances in bone modeling and remodeling, and extraskeletal calcification in arteries and soft tissues
- Renal osteodystrophy (OD): Only defines bone pathology associated with CKD
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Sharma AK et al: Deterioration of cortical bone microarchitecture: critical component of renal osteodystrophy evaluation. Am J Nephrol. 47(6):376-84, 2018
- Ketteler M et al: Executive summary of the 2017 KDIGO Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters. Kidney Int. 92(1):26-36, 2017
- Bover J et al: Adynamic bone disease: from bone to vessels in chronic kidney disease. Semin Nephrol. 34(6):626-40, 2014
- Kemper MJ et al: Renal osteodystrophy in children: pathogenesis, diagnosis and treatment. Curr Opin Pediatr. 26(2):180-6, 2014
- Torres PU et al: When, how, and why a bone biopsy should be performed in patients with chronic kidney disease. Semin Nephrol. 34(6):612-25, 2014
- Moorthi RN et al: Recent advances in the noninvasive diagnosis of renal osteodystrophy. Kidney Int. 84(5):886-94, 2013
- Sundaram M: Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
- Bardin T: Musculoskeletal manifestations of chronic renal failure. Curr Opin Rheumatol. 15(1):48-54, 2003
- Jevtic V: Imaging of renal osteodystrophy. Eur J Radiol. 46(2):85-95, 2003
- Paderni S et al: Vertebral localization of a brown tumor: description of a case and review of the literature. Chir Organi Mov. 88(1):83-91, 2003
- Spasovski GB et al: Spectrum of renal bone disease in end-stage renal failure patients not yet on dialysis. Nephrol Dial Transplant. 18(6):1159-66, 2003
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Renal osteodystrophy (OD)
Definitions
- Chronic kidney disease-mineral and bone disorder (CKD-MBD): Constellation of abnormalities seen in progressive kidney disease, including metabolic abnormalities, disturbances in bone modeling and remodeling, and extraskeletal calcification in arteries and soft tissues
- Renal osteodystrophy (OD): Only defines bone pathology associated with CKD
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Sharma AK et al: Deterioration of cortical bone microarchitecture: critical component of renal osteodystrophy evaluation. Am J Nephrol. 47(6):376-84, 2018
- Ketteler M et al: Executive summary of the 2017 KDIGO Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters. Kidney Int. 92(1):26-36, 2017
- Bover J et al: Adynamic bone disease: from bone to vessels in chronic kidney disease. Semin Nephrol. 34(6):626-40, 2014
- Kemper MJ et al: Renal osteodystrophy in children: pathogenesis, diagnosis and treatment. Curr Opin Pediatr. 26(2):180-6, 2014
- Torres PU et al: When, how, and why a bone biopsy should be performed in patients with chronic kidney disease. Semin Nephrol. 34(6):612-25, 2014
- Moorthi RN et al: Recent advances in the noninvasive diagnosis of renal osteodystrophy. Kidney Int. 84(5):886-94, 2013
- Sundaram M: Founders lecture 2007: Metabolic bone disease: what has changed in 30 years? Skeletal Radiol. 38(9):841-53, 2009
- Bardin T: Musculoskeletal manifestations of chronic renal failure. Curr Opin Rheumatol. 15(1):48-54, 2003
- Jevtic V: Imaging of renal osteodystrophy. Eur J Radiol. 46(2):85-95, 2003
- Paderni S et al: Vertebral localization of a brown tumor: description of a case and review of the literature. Chir Organi Mov. 88(1):83-91, 2003
- Spasovski GB et al: Spectrum of renal bone disease in end-stage renal failure patients not yet on dialysis. Nephrol Dial Transplant. 18(6):1159-66, 2003
