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Retromolar Trigone Squamous Cell Carcinoma
Nicholas A. Koontz, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Retromolar trigone (RMT) squamous cell carcinoma (SCCa)
            • Definitions

              • Oral cavity mucosal malignancy
              • RMT: Mucosa overlying ascending ramus of mandible posterior to molars, extending superiorly to maxillary tuberosity

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Hitchcock KE et al: Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery: a 10-year update. Am J Otolaryngol. 36(2):140-5, 2015
                                          2. Scher ED et al: Definitive chemoradiation for primary oral cavity carcinoma: A single institution experience. Oral Oncol. 51(7):709-15, 2015
                                          3. Mazziotti S et al: Diagnostic approach to retromolar trigone cancer by multiplanar computed tomography reconstructions. Can Assoc Radiol J. 65(4):335-44, 2014
                                          4. Deo SV et al: Aggressive multimodality management of locally advanced retromolar trigone tumors. Head Neck. 35(9):1269-73, 2013
                                          5. Erdogan N et al: Puffed-cheek computed tomography: a dynamic maneuver for imaging oral cavity tumors. Ear Nose Throat J. 91(9):383-4, 386, 2012
                                          6. Civantos FJ et al: Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: results of a prospective multi-institutional trial. J Clin Oncol. 28(8):1395-400, 2010
                                          7. Jerjes W et al: Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head Neck Oncol. 2:9, 2010
                                          8. Gomez DR et al: Intensity-modulated radiotherapy in postoperative treatment of oral cavity cancers. Int J Radiat Oncol Biol Phys. 73(4):1096-103, 2009
                                          9. Razfar A et al: Incidence and patterns of regional metastasis in early oral squamous cell cancers: feasibility of submandibular gland preservation. Head Neck. 31(12):1619-23, 2009
                                          10. Binahmed A et al: Population-based study of treatment outcomes in squamous cell carcinoma of the retromolar trigone. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104(5):662-5, 2007
                                          11. Hao SP et al: Treatment of squamous cell carcinoma of the retromolar trigone. Laryngoscope. 116(6):916-20, 2006
                                          12. Chong V: Oral cavity cancer. Cancer Imaging. 5 Spec No A:S49-52, 2005
                                          13. Kim ST et al: Chronic, reactive conditions of the oral cavity simulating mucosal carcinomas: CT and MR imaging findings with pathologic correlation in five patients. Clin Imaging. 29(6):406-11, 2005
                                          14. Mendenhall WM et al: Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery. Cancer. 103(11):2320-5, 2005
                                          15. Weissman JL et al: "Puffed-cheek" CT improves evaluation of the oral cavity. AJNR Am J Neuroradiol. 22(4):741-4, 2001
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Retromolar trigone (RMT) squamous cell carcinoma (SCCa)
                                                    • Definitions

                                                      • Oral cavity mucosal malignancy
                                                      • RMT: Mucosa overlying ascending ramus of mandible posterior to molars, extending superiorly to maxillary tuberosity

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Image Interpretation Pearls

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Hitchcock KE et al: Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery: a 10-year update. Am J Otolaryngol. 36(2):140-5, 2015
                                                                                  2. Scher ED et al: Definitive chemoradiation for primary oral cavity carcinoma: A single institution experience. Oral Oncol. 51(7):709-15, 2015
                                                                                  3. Mazziotti S et al: Diagnostic approach to retromolar trigone cancer by multiplanar computed tomography reconstructions. Can Assoc Radiol J. 65(4):335-44, 2014
                                                                                  4. Deo SV et al: Aggressive multimodality management of locally advanced retromolar trigone tumors. Head Neck. 35(9):1269-73, 2013
                                                                                  5. Erdogan N et al: Puffed-cheek computed tomography: a dynamic maneuver for imaging oral cavity tumors. Ear Nose Throat J. 91(9):383-4, 386, 2012
                                                                                  6. Civantos FJ et al: Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas: results of a prospective multi-institutional trial. J Clin Oncol. 28(8):1395-400, 2010
                                                                                  7. Jerjes W et al: Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head Neck Oncol. 2:9, 2010
                                                                                  8. Gomez DR et al: Intensity-modulated radiotherapy in postoperative treatment of oral cavity cancers. Int J Radiat Oncol Biol Phys. 73(4):1096-103, 2009
                                                                                  9. Razfar A et al: Incidence and patterns of regional metastasis in early oral squamous cell cancers: feasibility of submandibular gland preservation. Head Neck. 31(12):1619-23, 2009
                                                                                  10. Binahmed A et al: Population-based study of treatment outcomes in squamous cell carcinoma of the retromolar trigone. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 104(5):662-5, 2007
                                                                                  11. Hao SP et al: Treatment of squamous cell carcinoma of the retromolar trigone. Laryngoscope. 116(6):916-20, 2006
                                                                                  12. Chong V: Oral cavity cancer. Cancer Imaging. 5 Spec No A:S49-52, 2005
                                                                                  13. Kim ST et al: Chronic, reactive conditions of the oral cavity simulating mucosal carcinomas: CT and MR imaging findings with pathologic correlation in five patients. Clin Imaging. 29(6):406-11, 2005
                                                                                  14. Mendenhall WM et al: Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery. Cancer. 103(11):2320-5, 2005
                                                                                  15. Weissman JL et al: "Puffed-cheek" CT improves evaluation of the oral cavity. AJNR Am J Neuroradiol. 22(4):741-4, 2001