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Genitourinary
Diagnosis
Retroperitoneum
Malignant Neoplasms
Retroperitoneal and Mesenteric Lymphoma
Retroperitoneal and Mesenteric Lymphoma
Alice Fung, MD; Matthew T. Heller, MD, FSAR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Non-Hodgkin lymphoma (NHL), Hodgkin disease (HD)

          • Definitions

            • Malignancy of lymphatic system

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Levine I et al: Update on Hodgkin lymphoma from a radiologist's perspective. Clin Imaging. 65:65-77, 2020
                                            2. Cunningham J et al: Evolution of lymphoma staging and response evaluation: current limitations and future directions. Nat Rev Clin Oncol. 14(10):631-45, 2017
                                            3. Johnson SA et al: Imaging for staging and response assessment in lymphoma. Radiology. 276(2):323-38, 2015
                                            4. Scali EP et al: Primary retroperitoneal masses: what is the differential diagnosis? Abdom Imaging. 40(6):1887-903, 2015
                                            5. Barrington SF et al: Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol. 32(27):3048-58, 2014
                                            6. Cheson BD et al: Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 32(27):3059-68, 2014
                                            7. Kostakoglu L et al: Current role of FDG PET/CT in lymphoma. Eur J Nucl Med Mol Imaging. 41(5):1004-27, 2014
                                            8. Allen-Auerbach M et al: PET/computed tomography and lymphoma. Radiol Clin North Am. 51(5):833-44, 2013
                                            9. Heller MT et al: Managing incidental findings on abdominal and pelvic CT and MRI, part 3: white paper of the ACR Incidental Findings Committee II on splenic and nodal findings. J Am Coll Radiol. 10(11):833-9, 2013
                                            10. Manzella A et al: Abdominal manifestations of lymphoma: spectrum of imaging features. ISRN Radiol. 2013:483069, 2013
                                            11. Tateishi U et al: Nodal status of malignant lymphoma in pelvic and retroperitoneal lymphatic pathways: PET/CT. Abdom Imaging. 35(2):232-40, 2010
                                            12. Anis M et al: Imaging of abdominal lymphoma. Radiol Clin North Am. 46(2):265-85, viii-ix, 2008
                                            13. Lee WK et al: Abdominal manifestations of extranodal lymphoma: spectrum of imaging findings. AJR Am J Roentgenol. 191(1):198-206, 2008
                                            14. Morgan PB et al: Uncommon presentations of Hodgkin's disease. Case 1. Hodgkin's disease of the jejunum. J Clin Oncol. 22(1):193-5, 2004
                                            15. Ahmad A et al: Gastric mucosa-associated lymphoid tissue lymphoma. Am J Gastroenterol. 98(5):975-86, 2003
                                            16. O'Malley ME et al: US of gastrointestinal tract abnormalities with CT correlation. Radiographics. 23(1):59-72, 2003
                                            17. Sheth S et al: Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics. 23(2):457-73; quiz 535-6, 2003
                                            18. Vinnicombe SJ et al: Computerised tomography in the staging of Hodgkin's disease and non-Hodgkin's lymphoma. Eur J Nucl Med Mol Imaging. 30 Suppl 1:S42-55, 2003
                                            19. Apter S et al: Calcification in lymphoma occurring before therapy: CT features and clinical correlation. AJR Am J Roentgenol. 178(4):935-8, 2002
                                            20. Boni L et al: Primary pancreatic lymphoma. Surg Endosc. 16(7):1107-8, 2002
                                            21. Elis A et al: Detection of relapse in non-Hodgkin's lymphoma: role of routine follow-up studies. Am J Hematol. 69(1):41-4, 2002
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Non-Hodgkin lymphoma (NHL), Hodgkin disease (HD)

                                                    • Definitions

                                                      • Malignancy of lymphatic system

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Levine I et al: Update on Hodgkin lymphoma from a radiologist's perspective. Clin Imaging. 65:65-77, 2020
                                                                                      2. Cunningham J et al: Evolution of lymphoma staging and response evaluation: current limitations and future directions. Nat Rev Clin Oncol. 14(10):631-45, 2017
                                                                                      3. Johnson SA et al: Imaging for staging and response assessment in lymphoma. Radiology. 276(2):323-38, 2015
                                                                                      4. Scali EP et al: Primary retroperitoneal masses: what is the differential diagnosis? Abdom Imaging. 40(6):1887-903, 2015
                                                                                      5. Barrington SF et al: Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol. 32(27):3048-58, 2014
                                                                                      6. Cheson BD et al: Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol. 32(27):3059-68, 2014
                                                                                      7. Kostakoglu L et al: Current role of FDG PET/CT in lymphoma. Eur J Nucl Med Mol Imaging. 41(5):1004-27, 2014
                                                                                      8. Allen-Auerbach M et al: PET/computed tomography and lymphoma. Radiol Clin North Am. 51(5):833-44, 2013
                                                                                      9. Heller MT et al: Managing incidental findings on abdominal and pelvic CT and MRI, part 3: white paper of the ACR Incidental Findings Committee II on splenic and nodal findings. J Am Coll Radiol. 10(11):833-9, 2013
                                                                                      10. Manzella A et al: Abdominal manifestations of lymphoma: spectrum of imaging features. ISRN Radiol. 2013:483069, 2013
                                                                                      11. Tateishi U et al: Nodal status of malignant lymphoma in pelvic and retroperitoneal lymphatic pathways: PET/CT. Abdom Imaging. 35(2):232-40, 2010
                                                                                      12. Anis M et al: Imaging of abdominal lymphoma. Radiol Clin North Am. 46(2):265-85, viii-ix, 2008
                                                                                      13. Lee WK et al: Abdominal manifestations of extranodal lymphoma: spectrum of imaging findings. AJR Am J Roentgenol. 191(1):198-206, 2008
                                                                                      14. Morgan PB et al: Uncommon presentations of Hodgkin's disease. Case 1. Hodgkin's disease of the jejunum. J Clin Oncol. 22(1):193-5, 2004
                                                                                      15. Ahmad A et al: Gastric mucosa-associated lymphoid tissue lymphoma. Am J Gastroenterol. 98(5):975-86, 2003
                                                                                      16. O'Malley ME et al: US of gastrointestinal tract abnormalities with CT correlation. Radiographics. 23(1):59-72, 2003
                                                                                      17. Sheth S et al: Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics. 23(2):457-73; quiz 535-6, 2003
                                                                                      18. Vinnicombe SJ et al: Computerised tomography in the staging of Hodgkin's disease and non-Hodgkin's lymphoma. Eur J Nucl Med Mol Imaging. 30 Suppl 1:S42-55, 2003
                                                                                      19. Apter S et al: Calcification in lymphoma occurring before therapy: CT features and clinical correlation. AJR Am J Roentgenol. 178(4):935-8, 2002
                                                                                      20. Boni L et al: Primary pancreatic lymphoma. Surg Endosc. 16(7):1107-8, 2002
                                                                                      21. Elis A et al: Detection of relapse in non-Hodgkin's lymphoma: role of routine follow-up studies. Am J Hematol. 69(1):41-4, 2002