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Rhabdoid Tumor
Ethan A. Smith, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Malignant rhabdoid tumor, extracranial rhabdoid tumor
            • Definitions

              • Rare, highly aggressive neoplasm of young children with poor prognosis
              • Most commonly occurs in kidney

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Farmakis SG et al: Rhabdoid tumor: an aggressive renal medullary tumor of childhood. J Comput Assist Tomogr. 39(1):44-6, 2015
                                        2. Hong CR et al: Extra-cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience. Cancer Res Treat. 47(4):889-96, 2015
                                        3. Uwineza A et al: Rhabdoid tumor: the Irish experience 1986-2013. Cancer Genet. 207(9):398-402, 2014
                                        4. Gee MS et al: Magnetic resonance imaging of the pediatric kidney: benign and malignant masses. Magn Reson Imaging Clin N Am. 21(4):697-715, 2013
                                        5. Royer-Pokora B: Genetics of pediatric renal tumors. Pediatr Nephrol. 28(1):13-23, 2013
                                        6. Geller E et al: Renal neoplasms of childhood. Radiol Clin North Am. 49(4):689-709, vi, 2011
                                        7. van den Heuvel-Eibrink MM et al: Malignant rhabdoid tumours of the kidney (MRTKs), registered on recent SIOP protocols from 1993 to 2005: a report of the SIOP renal tumour study group. Pediatr Blood Cancer. 56(5):733-7, 2011
                                        8. Morgenstern DA et al: Clinical and pathological features of paediatric malignant rhabdoid tumours. Pediatr Blood Cancer. 54(1):29-34, 2010
                                        9. Tomlinson GE et al: Rhabdoid tumor of the kidney in the National Wilms' Tumor Study: age at diagnosis as a prognostic factor. J Clin Oncol. 23(30):7641-5, 2005
                                        10. Lowe LH et al: Pediatric renal masses: Wilms tumor and beyond. Radiographics. 20(6):1585-603, 2000
                                        11. Agrons GA et al: Rhabdoid tumor of the kidney in children: a comparative study of 21 cases. AJR Am J Roentgenol. 168(2):447-51, 1997
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Pathology

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Malignant rhabdoid tumor, extracranial rhabdoid tumor
                                                  • Definitions

                                                    • Rare, highly aggressive neoplasm of young children with poor prognosis
                                                    • Most commonly occurs in kidney

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Farmakis SG et al: Rhabdoid tumor: an aggressive renal medullary tumor of childhood. J Comput Assist Tomogr. 39(1):44-6, 2015
                                                                              2. Hong CR et al: Extra-cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience. Cancer Res Treat. 47(4):889-96, 2015
                                                                              3. Uwineza A et al: Rhabdoid tumor: the Irish experience 1986-2013. Cancer Genet. 207(9):398-402, 2014
                                                                              4. Gee MS et al: Magnetic resonance imaging of the pediatric kidney: benign and malignant masses. Magn Reson Imaging Clin N Am. 21(4):697-715, 2013
                                                                              5. Royer-Pokora B: Genetics of pediatric renal tumors. Pediatr Nephrol. 28(1):13-23, 2013
                                                                              6. Geller E et al: Renal neoplasms of childhood. Radiol Clin North Am. 49(4):689-709, vi, 2011
                                                                              7. van den Heuvel-Eibrink MM et al: Malignant rhabdoid tumours of the kidney (MRTKs), registered on recent SIOP protocols from 1993 to 2005: a report of the SIOP renal tumour study group. Pediatr Blood Cancer. 56(5):733-7, 2011
                                                                              8. Morgenstern DA et al: Clinical and pathological features of paediatric malignant rhabdoid tumours. Pediatr Blood Cancer. 54(1):29-34, 2010
                                                                              9. Tomlinson GE et al: Rhabdoid tumor of the kidney in the National Wilms' Tumor Study: age at diagnosis as a prognostic factor. J Clin Oncol. 23(30):7641-5, 2005
                                                                              10. Lowe LH et al: Pediatric renal masses: Wilms tumor and beyond. Radiographics. 20(6):1585-603, 2000
                                                                              11. Agrons GA et al: Rhabdoid tumor of the kidney in children: a comparative study of 21 cases. AJR Am J Roentgenol. 168(2):447-51, 1997