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Rhabdomyolysis
Jeffrey S. Ross, MD
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KEY FACTS

  • Terminology

    • Imaging Findings

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations and Synonyms

            • Rhabdomyolysis (RML), myonecrosis
          • Definitions

            • Clinical and biochemical syndrome resulting from damage of integrity of skeletal muscle, with release of toxic muscle cell components into circulation

          IMAGING FINDINGS

          • General Features

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            • Staging, Grading, or Classification Criteria

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Kisakol G et al: Rhabdomyolysis in a patient with hypothyroidism. Endocr J. 50(2):221-3, 2003
                                          2. Torres-Villalobos G et al: Pressure-induced rhabdomyolysis after bariatric surgery. Obes Surg. 13(2):297-301, 2003
                                          3. Wiltshire JP et al: Lumbar muscle rhabdomyolysis as a cause of acute renal failure after Roux-en-Y gastric bypass. Obes Surg. 13(2):306-13, 2003
                                          4. Atmaca H et al: Rhabdomyolysis associated with gemfibrozil-colchicine therapy. Ann Pharmacother. 36(11): 1719-21, 2002
                                          5. Barahona MJ et al: Hypothyroidism as a cause of rhabdomyolysis. Endocr J. 49(6): 621-3, 2002
                                          6. Black C et al: Etiology and frequency of rhabdomyolysis. Pharmacotherapy. 22(12): 1524-6, 2002
                                          7. Blanco JR et al: Rhabdomyolysis of infectious and noninfectious causes. South Med J. 95(5): 542-4, 2002
                                          8. Bocca G et al: Compartment syndrome, rhabdomyolysis and risk of acute renal failure as complications of the lithotomy position. J Nephrol. 15(2): 183-5, 2002
                                          9. Bolego C et al: Safety considerations for statins. Curr Opin Lipidol. 13(6): 637-44, 2002
                                          10. Criner JA et al: Rhabdomyolysis: the hidden killer. Medsurg Nurs. 11(3): 138-43, 155, 2002
                                          11. Evans M et al: The myotoxicity of statins. Curr Opin Lipidol. 13(4): 415-20, 2002
                                          12. Kikuno N et al: Traumatic rhabdomyolysis resulting from continuous compression in the exaggerated lithotomy position for radical perineal prostatectomy. Int J Urol. 9(9): 521-4, 2002
                                          13. Kratz A et al: Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am J Clin Pathol. 118(6): 856-63, 2002
                                          14. Kuang W et al: Rhabdomyolysis after laparoscopic donor nephrectomy. Urology. 60(5): 911, 2002
                                          15. Lappa A et al: Successful treatment of a complicated case of neuroleptic malignant syndrome. Intensive Care Med. 28(7): 976-7, 2002
                                          16. Masaoka S et al: Malignant lymphoma in skeletal muscle with rhabdomyolysis: a report of two cases. J Orthop Sci. 7(6):688-93, 2002
                                          17. Modi JR et al: Fluvastatin-induced rhabdomyolysis. Ann Pharmacother. 36(12): 1870-4, 2002
                                          18. Wexler RK: Evaluation and treatment of heat-related illnesses. Am Fam Physician. 65(11): 2307-14, 2002
                                          19. Getachew E et al: Pathologic quiz case: a man with exertion-induced cramps and myoglobinuria. McArdle disease (glycogenosis type V or myophosphorylase deficiency).
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging Findings

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations and Synonyms

                                                    • Rhabdomyolysis (RML), myonecrosis
                                                  • Definitions

                                                    • Clinical and biochemical syndrome resulting from damage of integrity of skeletal muscle, with release of toxic muscle cell components into circulation

                                                  IMAGING FINDINGS

                                                  • General Features

                                                    • CT Findings

                                                      • MR Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    • Staging, Grading, or Classification Criteria

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Kisakol G et al: Rhabdomyolysis in a patient with hypothyroidism. Endocr J. 50(2):221-3, 2003
                                                                                  2. Torres-Villalobos G et al: Pressure-induced rhabdomyolysis after bariatric surgery. Obes Surg. 13(2):297-301, 2003
                                                                                  3. Wiltshire JP et al: Lumbar muscle rhabdomyolysis as a cause of acute renal failure after Roux-en-Y gastric bypass. Obes Surg. 13(2):306-13, 2003
                                                                                  4. Atmaca H et al: Rhabdomyolysis associated with gemfibrozil-colchicine therapy. Ann Pharmacother. 36(11): 1719-21, 2002
                                                                                  5. Barahona MJ et al: Hypothyroidism as a cause of rhabdomyolysis. Endocr J. 49(6): 621-3, 2002
                                                                                  6. Black C et al: Etiology and frequency of rhabdomyolysis. Pharmacotherapy. 22(12): 1524-6, 2002
                                                                                  7. Blanco JR et al: Rhabdomyolysis of infectious and noninfectious causes. South Med J. 95(5): 542-4, 2002
                                                                                  8. Bocca G et al: Compartment syndrome, rhabdomyolysis and risk of acute renal failure as complications of the lithotomy position. J Nephrol. 15(2): 183-5, 2002
                                                                                  9. Bolego C et al: Safety considerations for statins. Curr Opin Lipidol. 13(6): 637-44, 2002
                                                                                  10. Criner JA et al: Rhabdomyolysis: the hidden killer. Medsurg Nurs. 11(3): 138-43, 155, 2002
                                                                                  11. Evans M et al: The myotoxicity of statins. Curr Opin Lipidol. 13(4): 415-20, 2002
                                                                                  12. Kikuno N et al: Traumatic rhabdomyolysis resulting from continuous compression in the exaggerated lithotomy position for radical perineal prostatectomy. Int J Urol. 9(9): 521-4, 2002
                                                                                  13. Kratz A et al: Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am J Clin Pathol. 118(6): 856-63, 2002
                                                                                  14. Kuang W et al: Rhabdomyolysis after laparoscopic donor nephrectomy. Urology. 60(5): 911, 2002
                                                                                  15. Lappa A et al: Successful treatment of a complicated case of neuroleptic malignant syndrome. Intensive Care Med. 28(7): 976-7, 2002
                                                                                  16. Masaoka S et al: Malignant lymphoma in skeletal muscle with rhabdomyolysis: a report of two cases. J Orthop Sci. 7(6):688-93, 2002
                                                                                  17. Modi JR et al: Fluvastatin-induced rhabdomyolysis. Ann Pharmacother. 36(12): 1870-4, 2002
                                                                                  18. Wexler RK: Evaluation and treatment of heat-related illnesses. Am Fam Physician. 65(11): 2307-14, 2002
                                                                                  19. Getachew E et al: Pathologic quiz case: a man with exertion-induced cramps and myoglobinuria. McArdle disease (glycogenosis type V or myophosphorylase deficiency).