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Pediatrics
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Cardiac
Miscellaneous
Rhabdomyoma
Rhabdomyoma
Randy R. Richardson, MD; Ryan A. Moore, MD; Paula J. Woodward, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Congenital cardiac hamartoma composed of abnormal myocytes

          IMAGING

          • General Features

            • Radiographic Findings

              • Echocardiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Tsoumani Z et al: Magnetic resonance imaging of intramyocardial fat deposition in tuberous sclerosis. Diagnostics (Basel). 10(12), 2020
                                        2. Victoria T et al: Imaging of fetal tumors and other dysplastic lesions: a review with emphasis on MR imaging. Prenat Diagn. 40(1):84-99, 2020
                                        3. Poterucha TJ et al: Cardiac tumors: clinical presentation, diagnosis, and management. Curr Treat Options Oncol. 20(8):66, 2019
                                        4. Ugurlucan M et al: Giant rhabdomyoma requiring emergency resection early after birth. Ann Thorac Surg. 107(1):e65, 2019
                                        5. Chen J et al: Fetal cardiac tumors: fetal echocardiography, clinical outcome and genetic analysis in 53 cases. Ultrasound Obstet Gynecol. 54(1):103-9, 2018
                                        6. Dragoumi P et al: Diagnosis of tuberous sclerosis complex in the fetus. Eur J Paediatr Neurol. 22(6):1027-34, 2018
                                        7. Palaskas N et al: Evaluation and management of cardiac tumors. Curr Treat Options Cardiovasc Med. 20(4):29, 2018
                                        8. von Ranke FM et al: Imaging of tuberous sclerosis complex: a pictorial review. Radiol Bras. 50(1):48-54, 2017
                                        9. Ying L et al: Primary cardiac tumors in children: a center's experience. J Cardiothorac Surg. 11(1):52, 2016
                                        10. Sciacca P et al: Rhabdomyomas and tuberous sclerosis complex: our experience in 33 cases. BMC Cardiovasc Disord. 14:66, 2014
                                        11. Tao TY et al: Pediatric cardiac tumors: clinical and imaging features. Radiographics. 34(4):1031-46, 2014
                                        12. Beroukhim RS et al: Characterization of cardiac tumors in children by cardiovascular magnetic resonance imaging a multicenter experience. J Am Coll Cardiol. 58(10):1044-54, 2011
                                        13. Miyake CY et al: Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardiol. 58(18):1903-9, 2011
                                        14. Tiberio D et al: Regression of a cardiac rhabdomyoma in a patient receiving everolimus. Pediatrics. 127(5):e1335-7, 2011
                                        15. Jain D et al: Benign cardiac tumors and tumorlike conditions. Ann Diagn Pathol. 14(3):215-30, 2010
                                        16. Yinon Y et al: Fetal cardiac tumors: a single-center experience of 40 cases. Prenat Diagn. 30(10):941-9, 2010
                                        17. Burke A et al: Pediatric heart tumors. Cardiovasc Pathol. 17(4):193-8, 2008
                                        18. Syed IS et al: MR imaging of cardiac masses. Magn Reson Imaging Clin N Am. 16(2):137-64, vii, 2008
                                        19. Kellenberger CJ et al: Cardiovascular MR imaging in neonates and infants with congenital heart disease. Radiographics. 27(1):5-18, 2007
                                        20. Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
                                        21. Kiaffas MG et al: Magnetic resonance imaging evaluation of cardiac tumor characteristics in infants and children. Am J Cardiol. 89(10):1229-33, 2002
                                        22. Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Definitions

                                                  • Congenital cardiac hamartoma composed of abnormal myocytes

                                                IMAGING

                                                • General Features

                                                  • Radiographic Findings

                                                    • Echocardiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Tsoumani Z et al: Magnetic resonance imaging of intramyocardial fat deposition in tuberous sclerosis. Diagnostics (Basel). 10(12), 2020
                                                                              2. Victoria T et al: Imaging of fetal tumors and other dysplastic lesions: a review with emphasis on MR imaging. Prenat Diagn. 40(1):84-99, 2020
                                                                              3. Poterucha TJ et al: Cardiac tumors: clinical presentation, diagnosis, and management. Curr Treat Options Oncol. 20(8):66, 2019
                                                                              4. Ugurlucan M et al: Giant rhabdomyoma requiring emergency resection early after birth. Ann Thorac Surg. 107(1):e65, 2019
                                                                              5. Chen J et al: Fetal cardiac tumors: fetal echocardiography, clinical outcome and genetic analysis in 53 cases. Ultrasound Obstet Gynecol. 54(1):103-9, 2018
                                                                              6. Dragoumi P et al: Diagnosis of tuberous sclerosis complex in the fetus. Eur J Paediatr Neurol. 22(6):1027-34, 2018
                                                                              7. Palaskas N et al: Evaluation and management of cardiac tumors. Curr Treat Options Cardiovasc Med. 20(4):29, 2018
                                                                              8. von Ranke FM et al: Imaging of tuberous sclerosis complex: a pictorial review. Radiol Bras. 50(1):48-54, 2017
                                                                              9. Ying L et al: Primary cardiac tumors in children: a center's experience. J Cardiothorac Surg. 11(1):52, 2016
                                                                              10. Sciacca P et al: Rhabdomyomas and tuberous sclerosis complex: our experience in 33 cases. BMC Cardiovasc Disord. 14:66, 2014
                                                                              11. Tao TY et al: Pediatric cardiac tumors: clinical and imaging features. Radiographics. 34(4):1031-46, 2014
                                                                              12. Beroukhim RS et al: Characterization of cardiac tumors in children by cardiovascular magnetic resonance imaging a multicenter experience. J Am Coll Cardiol. 58(10):1044-54, 2011
                                                                              13. Miyake CY et al: Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardiol. 58(18):1903-9, 2011
                                                                              14. Tiberio D et al: Regression of a cardiac rhabdomyoma in a patient receiving everolimus. Pediatrics. 127(5):e1335-7, 2011
                                                                              15. Jain D et al: Benign cardiac tumors and tumorlike conditions. Ann Diagn Pathol. 14(3):215-30, 2010
                                                                              16. Yinon Y et al: Fetal cardiac tumors: a single-center experience of 40 cases. Prenat Diagn. 30(10):941-9, 2010
                                                                              17. Burke A et al: Pediatric heart tumors. Cardiovasc Pathol. 17(4):193-8, 2008
                                                                              18. Syed IS et al: MR imaging of cardiac masses. Magn Reson Imaging Clin N Am. 16(2):137-64, vii, 2008
                                                                              19. Kellenberger CJ et al: Cardiovascular MR imaging in neonates and infants with congenital heart disease. Radiographics. 27(1):5-18, 2007
                                                                              20. Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
                                                                              21. Kiaffas MG et al: Magnetic resonance imaging evaluation of cardiac tumor characteristics in infants and children. Am J Cardiol. 89(10):1229-33, 2002
                                                                              22. Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000