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Rhabdomyoma
Eric Walker, MD, MHA, FACR, FACHE; Catherine C. Roberts, MD
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KEY FACTS

  • Imaging

    • Clinical Issues

      TERMINOLOGY

      • Abbreviations

        • Rhabdomyoma (RM)
        • Fetal RM (F-RM)
        • Adult RM (A-RM)
        • Genital RM (G-RM)
        • Cardiac RM (C-RM)
      • Definitions

        • Benign soft tissue tumor showing skeletal muscle differentiation
        • F-RM = benign neoplasm with immature skeletal muscle differentiation
        • A-RM = benign neoplasm with mature skeletal muscle differentiation
        • G-RM = benign neoplasm with mature skeletal muscle differentiation
        • C-RM = benign neoplasm arising from cardiac myocytes

      IMAGING

      • General Features

        • Radiographic Findings

          • CT Findings

            • MR Findings

              • Ultrasonographic Findings

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    • Gross Pathologic & Surgical Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                Selected References

                                1. Bajwa DS et al: Multifocal extracardiac rhabdomyomas: extending the phenotype of Birt-Hogg-Dubé syndrome. Br J Dermatol. 185(4):861-3, 2021
                                2. da Silva Leonel ACL et al: Oral adult rhabdomyoma. Head Neck Pathol. 15(4):1253-60, 2021
                                3. Khalaf MG et al: Multifocal adult rhabdomyoma of the head and neck: case report and systematic review of the literature. Int J Oral Maxillofac Surg. 50(3):327-34, 2021
                                4. Rashid T et al: Advances in the diagnosis and management of neonatal sarcomas. Clin Perinatol. 48(1):117-45, 2021
                                5. Parham DM: Rhabdomyoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 198-200, 2020
                                6. Díaz Angulo C et al: Imaging findings in cardiac masses (part I): study protocol and benign tumors. Radiologia. 57(6):480-8, 2015
                                7. Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 366-75, 2014
                                8. Sciacca P et al: Rhabdomyomas and tuberous sclerosis complex: our experience in 33 cases. BMC Cardiovasc Disord. 14:66, 2014
                                9. Tao TY et al: Pediatric cardiac tumors: clinical and imaging features. Radiographics. 34(4):1031-46, 2014
                                10. Weiss SW et al: Rhabdomyoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 583-94, 2008
                                11. Burke AP et al: Benign tumours with myocyte differentiation. In Travis WD et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart. IARC Press. 254-6, 2004
                                12. Kapadia SB et al: Rhabdomyoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 142-5, 2002
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Imaging

                                  • Clinical Issues

                                    TERMINOLOGY

                                    • Abbreviations

                                      • Rhabdomyoma (RM)
                                      • Fetal RM (F-RM)
                                      • Adult RM (A-RM)
                                      • Genital RM (G-RM)
                                      • Cardiac RM (C-RM)
                                    • Definitions

                                      • Benign soft tissue tumor showing skeletal muscle differentiation
                                      • F-RM = benign neoplasm with immature skeletal muscle differentiation
                                      • A-RM = benign neoplasm with mature skeletal muscle differentiation
                                      • G-RM = benign neoplasm with mature skeletal muscle differentiation
                                      • C-RM = benign neoplasm arising from cardiac myocytes

                                    IMAGING

                                    • General Features

                                      • Radiographic Findings

                                        • CT Findings

                                          • MR Findings

                                            • Ultrasonographic Findings

                                              DIFFERENTIAL DIAGNOSIS

                                                PATHOLOGY

                                                • General Features

                                                  • Gross Pathologic & Surgical Features

                                                    • Microscopic Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            • Treatment

                                                              Selected References

                                                              1. Bajwa DS et al: Multifocal extracardiac rhabdomyomas: extending the phenotype of Birt-Hogg-Dubé syndrome. Br J Dermatol. 185(4):861-3, 2021
                                                              2. da Silva Leonel ACL et al: Oral adult rhabdomyoma. Head Neck Pathol. 15(4):1253-60, 2021
                                                              3. Khalaf MG et al: Multifocal adult rhabdomyoma of the head and neck: case report and systematic review of the literature. Int J Oral Maxillofac Surg. 50(3):327-34, 2021
                                                              4. Rashid T et al: Advances in the diagnosis and management of neonatal sarcomas. Clin Perinatol. 48(1):117-45, 2021
                                                              5. Parham DM: Rhabdomyoma. In Fletcher CDM et al: World Health Organization Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 198-200, 2020
                                                              6. Díaz Angulo C et al: Imaging findings in cardiac masses (part I): study protocol and benign tumors. Radiologia. 57(6):480-8, 2015
                                                              7. Kransdorf MJ et al: Muscle tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 366-75, 2014
                                                              8. Sciacca P et al: Rhabdomyomas and tuberous sclerosis complex: our experience in 33 cases. BMC Cardiovasc Disord. 14:66, 2014
                                                              9. Tao TY et al: Pediatric cardiac tumors: clinical and imaging features. Radiographics. 34(4):1031-46, 2014
                                                              10. Weiss SW et al: Rhabdomyoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 583-94, 2008
                                                              11. Burke AP et al: Benign tumours with myocyte differentiation. In Travis WD et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart. IARC Press. 254-6, 2004
                                                              12. Kapadia SB et al: Rhabdomyoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 142-5, 2002