link
Bookmarks
Rhabdomyosarcoma
Catherine C. Roberts, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
11
0
2

KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Abbreviations

          • Rhabdomyosarcoma (RMS)
        • Synonyms

          • Embryonal RMS → malignant rhabdomyoma, rhabdomyosarcoma, myosarcoma, rhabdopoietic sarcoma, rhabdosarcoma, embryonal sarcoma
          • Alveolar RMS → monomorphous round cell rhabdomyosarcoma, rhabdomyoblastoma, rhabdomyopoietic sarcoma
        • Definitions

          • Malignant tumor showing skeletal muscle differentiation, with 3 main subtypes being embryonal, alveolar, and pleomorphic

        IMAGING

        • General Features

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Reporting Tips

                                            Selected References

                                            1. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                            2. Karunanithi S et al: Spectrum of physiologic and pathologic skeletal muscle (18)F-FDG uptake on PET/CT. AJR Am J Roentgenol. 205(2):W141-9, 2015
                                            3. Saboo SS et al: Imaging features of primary and secondary adult rhabdomyosarcoma. AJR Am J Roentgenol. 199(6):W694-703, 2012
                                            4. National Cancer Institute: Childhood Rhabdomyosarcoma Treatment. http://www.cancer.gov/cancertopics/pdq/treatment/childrhabdomyosarcoma/HealthProfessional/page6. Updated August 5, 2015. Accessed October 22, 2009
                                            5. Weiss SW et al: Rhabdomyosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 595-631, 2008
                                            6. Kransdorf MJ et al: Muscle Tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 312-24, 2006
                                            7. Breneman JC et al: Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma—a report from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol. 21(1):78-84, 2003
                                            8. Montgomery E et al: Pleomorphic rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 153-4, 2002
                                            9. Parham DM et al: Alveolar rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 150-2, 2002
                                            10. Parham DM et al: Embryonal rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 146-9, 2002
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Rhabdomyosarcoma (RMS)
                                                  • Synonyms

                                                    • Embryonal RMS → malignant rhabdomyoma, rhabdomyosarcoma, myosarcoma, rhabdopoietic sarcoma, rhabdosarcoma, embryonal sarcoma
                                                    • Alveolar RMS → monomorphous round cell rhabdomyosarcoma, rhabdomyoblastoma, rhabdomyopoietic sarcoma
                                                  • Definitions

                                                    • Malignant tumor showing skeletal muscle differentiation, with 3 main subtypes being embryonal, alveolar, and pleomorphic

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                                                                      2. Karunanithi S et al: Spectrum of physiologic and pathologic skeletal muscle (18)F-FDG uptake on PET/CT. AJR Am J Roentgenol. 205(2):W141-9, 2015
                                                                                      3. Saboo SS et al: Imaging features of primary and secondary adult rhabdomyosarcoma. AJR Am J Roentgenol. 199(6):W694-703, 2012
                                                                                      4. National Cancer Institute: Childhood Rhabdomyosarcoma Treatment. http://www.cancer.gov/cancertopics/pdq/treatment/childrhabdomyosarcoma/HealthProfessional/page6. Updated August 5, 2015. Accessed October 22, 2009
                                                                                      5. Weiss SW et al: Rhabdomyosarcoma. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 595-631, 2008
                                                                                      6. Kransdorf MJ et al: Muscle Tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 312-24, 2006
                                                                                      7. Breneman JC et al: Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma—a report from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol. 21(1):78-84, 2003
                                                                                      8. Montgomery E et al: Pleomorphic rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 153-4, 2002
                                                                                      9. Parham DM et al: Alveolar rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 150-2, 2002
                                                                                      10. Parham DM et al: Embryonal rhabdomyosarcoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 146-9, 2002