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Rheumatoid Nodule
Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Nonneoplastic soft tissue nodule that is most common extraarticular manifestation of rheumatoid arthritis

          IMAGING

          • General Features

            • Radiographic Findings

              • MR Findings

                • Nuclear Medicine Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                Selected References

                                1. Plymale M et al: Isolated intra-articular pseudorheumatoid nodule of the knee. Skeletal Radiol. 40(4):463-6, 2011
                                2. Amini S et al: A novel treatment for rheumatoid nodules (RN) with intralesional fluorouracil. Int J Dermatol. 48(5):543-6, 2009
                                3. Strobel K et al: FDG uptake in a rheumatoid nodule with imaging appearance similar to a malignant soft tissue tumor. Clin Nucl Med. 34(10):691-2, 2009
                                4. Thinda S et al: Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature. World J Surg Oncol. 7:59, 2009
                                5. Osanai T et al: Large benign rheumatoid nodules of the trunk in an elderly patient: radiologic appearance mimicking a soft-tissue sarcoma. Mod Rheumatol. 16(5):312-5, 2006
                                6. Resnick D: Rheumatoid arthritis and the seronegative spondyloarthropathies: radiographic and pathologic concepts. In Resnick D et al: Diagnosis of Bone and Joint Disorders. 4th ed. Philadelphia: W.B. Saunders. 860-3, 2002
                                7. Sanders TG et al: Rheumatoid nodule of the foot: MRI appearances mimicking an indeterminate soft tissue mass. Skeletal Radiol. 27(8):457-60, 1998
                                8. Starok M et al: Rheumatoid nodules: MRI characteristics. Clin Imaging. 22(3):216-9, 1998
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Pathology

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Definitions

                                          • Nonneoplastic soft tissue nodule that is most common extraarticular manifestation of rheumatoid arthritis

                                        IMAGING

                                        • General Features

                                          • Radiographic Findings

                                            • MR Findings

                                              • Nuclear Medicine Findings

                                                DIFFERENTIAL DIAGNOSIS

                                                  PATHOLOGY

                                                  • General Features

                                                    • Microscopic Features

                                                      CLINICAL ISSUES

                                                      • Presentation

                                                        • Demographics

                                                          • Natural History & Prognosis

                                                            • Treatment

                                                              Selected References

                                                              1. Plymale M et al: Isolated intra-articular pseudorheumatoid nodule of the knee. Skeletal Radiol. 40(4):463-6, 2011
                                                              2. Amini S et al: A novel treatment for rheumatoid nodules (RN) with intralesional fluorouracil. Int J Dermatol. 48(5):543-6, 2009
                                                              3. Strobel K et al: FDG uptake in a rheumatoid nodule with imaging appearance similar to a malignant soft tissue tumor. Clin Nucl Med. 34(10):691-2, 2009
                                                              4. Thinda S et al: Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature. World J Surg Oncol. 7:59, 2009
                                                              5. Osanai T et al: Large benign rheumatoid nodules of the trunk in an elderly patient: radiologic appearance mimicking a soft-tissue sarcoma. Mod Rheumatol. 16(5):312-5, 2006
                                                              6. Resnick D: Rheumatoid arthritis and the seronegative spondyloarthropathies: radiographic and pathologic concepts. In Resnick D et al: Diagnosis of Bone and Joint Disorders. 4th ed. Philadelphia: W.B. Saunders. 860-3, 2002
                                                              7. Sanders TG et al: Rheumatoid nodule of the foot: MRI appearances mimicking an indeterminate soft tissue mass. Skeletal Radiol. 27(8):457-60, 1998
                                                              8. Starok M et al: Rheumatoid nodules: MRI characteristics. Clin Imaging. 22(3):216-9, 1998