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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Rheumatoid arthritis (RA)
Definitions
- Inflammatory soft tissue nodule that is most common extraarticular manifestation of RA
IMAGING
General Features
Radiographic Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Molecular/Cytogenetics/Stains
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Murphy D et al: Nodular rheumatoid arthritis (RA): a distinct disease subtype, initiated by cadmium inhalation inducing pulmonary nodule formation and subsequent RA-associated autoantibody generation. Med Hypotheses. 122:48-55, 2019
- Marcucci E et al: Extra-articular rheumatoid arthritis. Reumatismo. 70(4):212-24, 2018
- Verheul MK et al: Triple positivity for anti-citrullinated protein autoantibodies, rheumatoid factor, and anti-carbamylated protein antibodies conferring high specificity for rheumatoid arthritis: implications for very early identification of at-risk individuals. Arthritis Rheumatol. 70(11):1721-31, 2018
- Tilstra JS et al: Rheumatoid nodules. Dermatol Clin. 33(3):361-71, 2015
- Plymale M et al: Isolated intra-articular pseudorheumatoid nodule of the knee. Skeletal Radiol. 40(4):463-6, 2011
- Amini S et al: A novel treatment for rheumatoid nodules (RN) with intralesional fluorouracil. Int J Dermatol. 48(5):543-6, 2009
- Strobel K et al: FDG uptake in a rheumatoid nodule with imaging appearance similar to a malignant soft tissue tumor. Clin Nucl Med. 34(10):691-2, 2009
- Thinda S et al: Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature. World J Surg Oncol. 7:59, 2009
- Knoess M et al: Colocalization of C4d deposits/CD68+ macrophages in rheumatoid nodule and granuloma annulare: immunohistochemical evidence of a complement-mediated mechanism in fibrinoid necrosis. Pathol Res Pract. 204(6):373-8, 2008
- Osanai T et al: Large benign rheumatoid nodules of the trunk in an elderly patient: radiologic appearance mimicking a soft-tissue sarcoma. Mod Rheumatol. 16(5):312-5, 2006
- Resnick D: Rheumatoid arthritis and the seronegative spondyloarthropathies: radiographic and pathologic concepts. In Resnick D et al: Diagnosis of Bone and Joint Disorders. 4th ed. W.B. Saunders. 860-3, 2002
- Sanders TG et al: Rheumatoid nodule of the foot: MRI appearances mimicking an indeterminate soft tissue mass. Skeletal Radiol. 27(8):457-60, 1998
- Starok M et al: Rheumatoid nodules: MRI characteristics. Clin Imaging. 22(3):216-9, 1998
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
- Rheumatoid arthritis (RA)
Definitions
- Inflammatory soft tissue nodule that is most common extraarticular manifestation of RA
IMAGING
General Features
Radiographic Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Molecular/Cytogenetics/Stains
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
- Murphy D et al: Nodular rheumatoid arthritis (RA): a distinct disease subtype, initiated by cadmium inhalation inducing pulmonary nodule formation and subsequent RA-associated autoantibody generation. Med Hypotheses. 122:48-55, 2019
- Marcucci E et al: Extra-articular rheumatoid arthritis. Reumatismo. 70(4):212-24, 2018
- Verheul MK et al: Triple positivity for anti-citrullinated protein autoantibodies, rheumatoid factor, and anti-carbamylated protein antibodies conferring high specificity for rheumatoid arthritis: implications for very early identification of at-risk individuals. Arthritis Rheumatol. 70(11):1721-31, 2018
- Tilstra JS et al: Rheumatoid nodules. Dermatol Clin. 33(3):361-71, 2015
- Plymale M et al: Isolated intra-articular pseudorheumatoid nodule of the knee. Skeletal Radiol. 40(4):463-6, 2011
- Amini S et al: A novel treatment for rheumatoid nodules (RN) with intralesional fluorouracil. Int J Dermatol. 48(5):543-6, 2009
- Strobel K et al: FDG uptake in a rheumatoid nodule with imaging appearance similar to a malignant soft tissue tumor. Clin Nucl Med. 34(10):691-2, 2009
- Thinda S et al: Mesenteric rheumatoid nodules masquerading as an intra-abdominal malignancy: a case report and review of the literature. World J Surg Oncol. 7:59, 2009
- Knoess M et al: Colocalization of C4d deposits/CD68+ macrophages in rheumatoid nodule and granuloma annulare: immunohistochemical evidence of a complement-mediated mechanism in fibrinoid necrosis. Pathol Res Pract. 204(6):373-8, 2008
- Osanai T et al: Large benign rheumatoid nodules of the trunk in an elderly patient: radiologic appearance mimicking a soft-tissue sarcoma. Mod Rheumatol. 16(5):312-5, 2006
- Resnick D: Rheumatoid arthritis and the seronegative spondyloarthropathies: radiographic and pathologic concepts. In Resnick D et al: Diagnosis of Bone and Joint Disorders. 4th ed. W.B. Saunders. 860-3, 2002
- Sanders TG et al: Rheumatoid nodule of the foot: MRI appearances mimicking an indeterminate soft tissue mass. Skeletal Radiol. 27(8):457-60, 1998
- Starok M et al: Rheumatoid nodules: MRI characteristics. Clin Imaging. 22(3):216-9, 1998
