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Rickettsial Diseases
Miral D. Jhaveri, MD; Laurie A. Loevner, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Pathology

        • Clinical Issues

          TERMINOLOGY

          • Abbreviations

            • Rocky Mountain spotted fever (RMS), Q fever, epidemic typhus (ET)
          • Synonyms

            • Tick typhus, Tobia fever (Colombia), febre maculosa (Brazil), fiebre manchada (Mexico)
          • Definitions

            • Zoonotic infections of squirrels and other animals → ticks carrying Rickettsia → humans
              • Exception is Q fever (caused by Coxiella burnetii) transmitted by inhalation

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Microscopic Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  Selected References

                                  1. Delord M et al: Rickettsioses and Q fever in travelers (2004-2013). Travel Med Infect Dis. 12(5):443-58, 2014
                                  2. Hart BL et al: Armies of Pestilence: CNS Infections as Potential Weapons of Mass Destruction. AJNR Am J Neuroradiol. ePub, 2014
                                  3. Parola P et al: Update on tick-borne rickettsioses around the world: a geographic approach. Clin Microbiol Rev. 26(4):657-702, 2013
                                  4. Akgoz A et al: Imaging of rickettsial, spirochetal, and parasitic infections. Neuroimaging Clin N Am. 22(4):633-57, 2012
                                  5. Aliaga L et al: Mediterranean spotted fever with encephalitis. J Med Microbiol. 58(Pt 4):521-5, 2009
                                  6. Singh-Behl D et al: Tick-borne infections. Dermatol Clin. 21(2):237-44, v, 2003
                                  7. Walker DH et al: Pathogenic mechanisms of diseases caused by Rickettsia. Ann N Y Acad Sci. 990:1-11, 2003
                                  8. Warner RD et al: Rocky Mountain spotted fever. J Am Vet Med Assoc. 221(10):1413-7, 2002
                                  9. Bonawitz C et al: Comparison of CT and MR features with clinical outcome in patients with Rocky Mountain spotted fever. AJNR Am J Neuroradiol. 18(3):459-64, 1997
                                  10. Baganz MD et al: Rocky Mountain spotted fever encephalitis: MR findings. AJNR Am J Neuroradiol. 16(4 Suppl):919-22, 1995
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Pathology

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Abbreviations

                                            • Rocky Mountain spotted fever (RMS), Q fever, epidemic typhus (ET)
                                          • Synonyms

                                            • Tick typhus, Tobia fever (Colombia), febre maculosa (Brazil), fiebre manchada (Mexico)
                                          • Definitions

                                            • Zoonotic infections of squirrels and other animals → ticks carrying Rickettsia → humans
                                              • Exception is Q fever (caused by Coxiella burnetii) transmitted by inhalation

                                          IMAGING

                                          • General Features

                                            • CT Findings

                                              • MR Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    PATHOLOGY

                                                    • General Features

                                                      • Microscopic Features

                                                        CLINICAL ISSUES

                                                        • Presentation

                                                          • Demographics

                                                            • Natural History & Prognosis

                                                              • Treatment

                                                                DIAGNOSTIC CHECKLIST

                                                                • Consider

                                                                  Selected References

                                                                  1. Delord M et al: Rickettsioses and Q fever in travelers (2004-2013). Travel Med Infect Dis. 12(5):443-58, 2014
                                                                  2. Hart BL et al: Armies of Pestilence: CNS Infections as Potential Weapons of Mass Destruction. AJNR Am J Neuroradiol. ePub, 2014
                                                                  3. Parola P et al: Update on tick-borne rickettsioses around the world: a geographic approach. Clin Microbiol Rev. 26(4):657-702, 2013
                                                                  4. Akgoz A et al: Imaging of rickettsial, spirochetal, and parasitic infections. Neuroimaging Clin N Am. 22(4):633-57, 2012
                                                                  5. Aliaga L et al: Mediterranean spotted fever with encephalitis. J Med Microbiol. 58(Pt 4):521-5, 2009
                                                                  6. Singh-Behl D et al: Tick-borne infections. Dermatol Clin. 21(2):237-44, v, 2003
                                                                  7. Walker DH et al: Pathogenic mechanisms of diseases caused by Rickettsia. Ann N Y Acad Sci. 990:1-11, 2003
                                                                  8. Warner RD et al: Rocky Mountain spotted fever. J Am Vet Med Assoc. 221(10):1413-7, 2002
                                                                  9. Bonawitz C et al: Comparison of CT and MR features with clinical outcome in patients with Rocky Mountain spotted fever. AJNR Am J Neuroradiol. 18(3):459-64, 1997
                                                                  10. Baganz MD et al: Rocky Mountain spotted fever encephalitis: MR findings. AJNR Am J Neuroradiol. 16(4 Suppl):919-22, 1995