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Rosette-Forming Glioneuronal Tumor
Karen L. Salzman, MD; Majda M. Thurnher, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Rosette-forming glioneuronal tumor (RGNT)
              • Synonyms

                • 1st described as dysembryoplastic neuroepithelial tumor (DNT) of cerebellum
                • Also formerly called cerebellar DNT
              • Definitions

                • Rare, slowly growing benign tumor
                  • 4th ventricle most common (sometimes called RGNT of 4th ventricle)

              IMAGING

              • General Features

                • Imaging Recommendations

                  • CT Findings

                    • MR Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Allinson KS et al: Rosette-forming glioneuronal tumor with dissemination throughout the ventricular system: a case report. Clin Neuropathol. 34(2):64-9, 2015
                                          2. García Cabezas S et al: Rosette-forming glioneuronal tumour (RGNT) of the fourth ventricle: a highly aggressive case. Brain Tumor Pathol. 32(2):124-30, 2015
                                          3. Schlamann A et al: An individual patient data meta-analysis on characteristics and outcome of patients with papillary glioneuronal tumor, rosette glioneuronal tumor with neuropil-like islands and rosette forming glioneuronal tumor of the fourth ventricle. PLoS One. 9(7):e101211, 2014
                                          4. Smith AB et al: From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics. 33(1):21-43, 2013
                                          5. Zhang J et al: A comprehensive analysis of 41 patients with rosette-forming glioneuronal tumors of the fourth ventricle. J Clin Neurosci. 20(3):335-41, 2013
                                          6. Hsu C et al: Rosette-forming glioneuronal tumour: Imaging features, histopathological correlation and a comprehensive review of literature. Br J Neurosurg. 26(5):668-73, 2012
                                          7. Marhold F et al: Clinicoradiological features of rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: report of four cases and literature review. J Neurooncol. 90(3):301-8, 2008
                                          8. Komori T et al: A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor? Am J Surg Pathol. 26(5):582-91, 2002
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Rosette-forming glioneuronal tumor (RGNT)
                                                      • Synonyms

                                                        • 1st described as dysembryoplastic neuroepithelial tumor (DNT) of cerebellum
                                                        • Also formerly called cerebellar DNT
                                                      • Definitions

                                                        • Rare, slowly growing benign tumor
                                                          • 4th ventricle most common (sometimes called RGNT of 4th ventricle)

                                                      IMAGING

                                                      • General Features

                                                        • Imaging Recommendations

                                                          • CT Findings

                                                            • MR Findings

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Allinson KS et al: Rosette-forming glioneuronal tumor with dissemination throughout the ventricular system: a case report. Clin Neuropathol. 34(2):64-9, 2015
                                                                                  2. García Cabezas S et al: Rosette-forming glioneuronal tumour (RGNT) of the fourth ventricle: a highly aggressive case. Brain Tumor Pathol. 32(2):124-30, 2015
                                                                                  3. Schlamann A et al: An individual patient data meta-analysis on characteristics and outcome of patients with papillary glioneuronal tumor, rosette glioneuronal tumor with neuropil-like islands and rosette forming glioneuronal tumor of the fourth ventricle. PLoS One. 9(7):e101211, 2014
                                                                                  4. Smith AB et al: From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics. 33(1):21-43, 2013
                                                                                  5. Zhang J et al: A comprehensive analysis of 41 patients with rosette-forming glioneuronal tumors of the fourth ventricle. J Clin Neurosci. 20(3):335-41, 2013
                                                                                  6. Hsu C et al: Rosette-forming glioneuronal tumour: Imaging features, histopathological correlation and a comprehensive review of literature. Br J Neurosurg. 26(5):668-73, 2012
                                                                                  7. Marhold F et al: Clinicoradiological features of rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: report of four cases and literature review. J Neurooncol. 90(3):301-8, 2008
                                                                                  8. Komori T et al: A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor? Am J Surg Pathol. 26(5):582-91, 2002