Malignant tumor with morphologic features identical to nonkeratinizing undifferentiated nasopharyngeal carcinoma (NPC), according to WHO classification
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Blood Tests
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Wenig BM: Lymphoepithelial-like carcinomas of the head and neck. Semin Diagn Pathol. 32(1):74-86, 2015
Ban X et al: Lymphoepithelial carcinoma of the salivary gland: morphologic patterns and imaging features on CT and MRI. AJNR Am J Neuroradiol. 35(9):1813-9, 2014
Ambrosio MR et al: Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature. Diagn Pathol. 8(1):115, 2013
Ma H et al: Primary lymphoepithelioma-like carcinoma of salivary gland: 69 cases with long-term follow-up. Head Neck. Epub ahead of print, 2013
Friborg J et al: A spectrum of basaloid morphology in a subset of EBV-associated "lymphoepithelial carcinomas" of major salivary glands. Head Neck Pathol. 6(4):445-50, 2012
Schneider M et al: Lymphoepithelial carcinoma of the parotid glands and its relationship with benign lymphoepithelial lesions. Arch Pathol Lab Med. 132(2):278-82, 2008
Hsiung CY et al: Lymphoepithelioma-like carcinoma of salivary glands: treatment results and failure patterns. Br J Radiol. 79(937):52-5, 2006
Wang CP et al: Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer. 101(9):2020-7, 2004
Wu DL et al: Malignant lymphoepithelial lesion of the parotid gland: a case report and review of the literature. Ear Nose Throat J. 80(11):803-6, 2001
Ahuja AT et al: Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas. Clin Radiol. 54(5):289-93, 1999
Dubey P et al: Nonnasopharyngeal lymphoepithelioma of the head and neck. Cancer. 82(8):1556-62, 1998
Kuo T et al: Lymphoepithelioma-like salivary gland carcinoma in Taiwan: a clinicopathological study of nine cases demonstrating a strong association with Epstein-Barr virus. Histopathology. 31(1):75-82, 1997
Abdulla AK et al: Lymphoepithelial carcinoma of salivary glands. Head Neck. 18(6):577-81, 1996
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
Lymphoepithelioma-like carcinoma (LELC)
Synonyms
Lymphoepithelial carcinoma
Malignant lymphoepithelial lesion
Undifferentiated carcinoma with lymphoid stroma
Eskimoma (old term, no longer used)
Definitions
Malignant tumor with morphologic features identical to nonkeratinizing undifferentiated nasopharyngeal carcinoma (NPC), according to WHO classification
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Blood Tests
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Wenig BM: Lymphoepithelial-like carcinomas of the head and neck. Semin Diagn Pathol. 32(1):74-86, 2015
Ban X et al: Lymphoepithelial carcinoma of the salivary gland: morphologic patterns and imaging features on CT and MRI. AJNR Am J Neuroradiol. 35(9):1813-9, 2014
Ambrosio MR et al: Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature. Diagn Pathol. 8(1):115, 2013
Ma H et al: Primary lymphoepithelioma-like carcinoma of salivary gland: 69 cases with long-term follow-up. Head Neck. Epub ahead of print, 2013
Friborg J et al: A spectrum of basaloid morphology in a subset of EBV-associated "lymphoepithelial carcinomas" of major salivary glands. Head Neck Pathol. 6(4):445-50, 2012
Schneider M et al: Lymphoepithelial carcinoma of the parotid glands and its relationship with benign lymphoepithelial lesions. Arch Pathol Lab Med. 132(2):278-82, 2008
Hsiung CY et al: Lymphoepithelioma-like carcinoma of salivary glands: treatment results and failure patterns. Br J Radiol. 79(937):52-5, 2006
Wang CP et al: Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer. 101(9):2020-7, 2004
Wu DL et al: Malignant lymphoepithelial lesion of the parotid gland: a case report and review of the literature. Ear Nose Throat J. 80(11):803-6, 2001
Ahuja AT et al: Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas. Clin Radiol. 54(5):289-93, 1999
Dubey P et al: Nonnasopharyngeal lymphoepithelioma of the head and neck. Cancer. 82(8):1556-62, 1998
Kuo T et al: Lymphoepithelioma-like salivary gland carcinoma in Taiwan: a clinicopathological study of nine cases demonstrating a strong association with Epstein-Barr virus. Histopathology. 31(1):75-82, 1997
Abdulla AK et al: Lymphoepithelial carcinoma of salivary glands. Head Neck. 18(6):577-81, 1996
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