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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Lymphoepithelioma-like carcinoma (LELC)
Synonyms
- Lymphoepithelial carcinoma
- Malignant lymphoepithelial lesion
- Undifferentiated carcinoma with lymphoid stroma
- Eskimoma (old term, no longer used)
Definitions
- Malignant tumor with morphologic features identical to nonkeratinizing undifferentiated nasopharyngeal carcinoma (NPC), according to WHO classification
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Blood Tests
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Wenig BM: Lymphoepithelial-like carcinomas of the head and neck. Semin Diagn Pathol. 32(1):74-86, 2015
- Ban X et al: Lymphoepithelial carcinoma of the salivary gland: morphologic patterns and imaging features on CT and MRI. AJNR Am J Neuroradiol. 35(9):1813-9, 2014
- Ambrosio MR et al: Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature. Diagn Pathol. 8(1):115, 2013
- Ma H et al: Primary lymphoepithelioma-like carcinoma of salivary gland: 69 cases with long-term follow-up. Head Neck. Epub ahead of print, 2013
- Friborg J et al: A spectrum of basaloid morphology in a subset of EBV-associated "lymphoepithelial carcinomas" of major salivary glands. Head Neck Pathol. 6(4):445-50, 2012
- Schneider M et al: Lymphoepithelial carcinoma of the parotid glands and its relationship with benign lymphoepithelial lesions. Arch Pathol Lab Med. 132(2):278-82, 2008
- Hsiung CY et al: Lymphoepithelioma-like carcinoma of salivary glands: treatment results and failure patterns. Br J Radiol. 79(937):52-5, 2006
- Wang CP et al: Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer. 101(9):2020-7, 2004
- Wu DL et al: Malignant lymphoepithelial lesion of the parotid gland: a case report and review of the literature. Ear Nose Throat J. 80(11):803-6, 2001
- Ahuja AT et al: Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas. Clin Radiol. 54(5):289-93, 1999
- Dubey P et al: Nonnasopharyngeal lymphoepithelioma of the head and neck. Cancer. 82(8):1556-62, 1998
- Kuo T et al: Lymphoepithelioma-like salivary gland carcinoma in Taiwan: a clinicopathological study of nine cases demonstrating a strong association with Epstein-Barr virus. Histopathology. 31(1):75-82, 1997
- Abdulla AK et al: Lymphoepithelial carcinoma of salivary glands. Head Neck. 18(6):577-81, 1996
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Lymphoepithelioma-like carcinoma (LELC)
Synonyms
- Lymphoepithelial carcinoma
- Malignant lymphoepithelial lesion
- Undifferentiated carcinoma with lymphoid stroma
- Eskimoma (old term, no longer used)
Definitions
- Malignant tumor with morphologic features identical to nonkeratinizing undifferentiated nasopharyngeal carcinoma (NPC), according to WHO classification
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Blood Tests
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
- Wenig BM: Lymphoepithelial-like carcinomas of the head and neck. Semin Diagn Pathol. 32(1):74-86, 2015
- Ban X et al: Lymphoepithelial carcinoma of the salivary gland: morphologic patterns and imaging features on CT and MRI. AJNR Am J Neuroradiol. 35(9):1813-9, 2014
- Ambrosio MR et al: Lymphoepithelial-like carcinoma of the parotid gland: a case report and a brief review of the western literature. Diagn Pathol. 8(1):115, 2013
- Ma H et al: Primary lymphoepithelioma-like carcinoma of salivary gland: 69 cases with long-term follow-up. Head Neck. Epub ahead of print, 2013
- Friborg J et al: A spectrum of basaloid morphology in a subset of EBV-associated "lymphoepithelial carcinomas" of major salivary glands. Head Neck Pathol. 6(4):445-50, 2012
- Schneider M et al: Lymphoepithelial carcinoma of the parotid glands and its relationship with benign lymphoepithelial lesions. Arch Pathol Lab Med. 132(2):278-82, 2008
- Hsiung CY et al: Lymphoepithelioma-like carcinoma of salivary glands: treatment results and failure patterns. Br J Radiol. 79(937):52-5, 2006
- Wang CP et al: Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands. Cancer. 101(9):2020-7, 2004
- Wu DL et al: Malignant lymphoepithelial lesion of the parotid gland: a case report and review of the literature. Ear Nose Throat J. 80(11):803-6, 2001
- Ahuja AT et al: Palatal lymphoepitheliomas and a review of head and neck lymphoepitheliomas. Clin Radiol. 54(5):289-93, 1999
- Dubey P et al: Nonnasopharyngeal lymphoepithelioma of the head and neck. Cancer. 82(8):1556-62, 1998
- Kuo T et al: Lymphoepithelioma-like salivary gland carcinoma in Taiwan: a clinicopathological study of nine cases demonstrating a strong association with Epstein-Barr virus. Histopathology. 31(1):75-82, 1997
- Abdulla AK et al: Lymphoepithelial carcinoma of salivary glands. Head Neck. 18(6):577-81, 1996
