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Salivary Gland Scintigraphy
Paige Bennett, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • 3 major pairs of exocrine salivary glands secrete saliva into mouth through ducts
            • Parotid glands
              • Anterior and inferior to ears
              • Function during meals or with thought/smell of food
              • Secrete saliva into mouth through parotid/Stensen duct 
            • Submandibular glands
              • Under mandible in floor of mouth
              • Continuously produce saliva
              • Secrete saliva into mouth through submandibular/Wharton/submaxillary duct 
            • Sublingual glands
              • In floor of mouth, lateral to tongue
              • Continuously produce saliva
              • Secrete saliva through ducts of Rivinus
          • Dysfunction can occur due to
            • Sjögren syndrome (autoimmune disease)
            • Iatrogenic
              • External beam radiation therapy
              • Radioactive iodine (I-131) therapy
              • Postsurgical
            • Sialadenitis (infection)
            • Sialolithiasis (stones)
            • Benign and malignant neoplasms

        IMAGING

        • General Features

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        CLINICAL ISSUES

                        • Presentation

                          • Treatment

                            DIAGNOSTIC CHECKLIST

                            • Consider

                              Selected References

                              1. Kaldeway HP et al: Validation of quantitative salivary gland scintigraphy in relation to the American-European concensus criteria for Sjögren's syndrome. Nucl Med Commun. 40(4):343-8, 2019
                              2. Afzelius P et al: Imaging of the major salivary glands. Clin Physiol Funct Imaging. 36(1):1-10, 2016
                              3. MacDonald A et al: Infrequently performed studies in nuclear medicine: part 2. J Nucl Med Technol. 37(1):1-13, 2009
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Imaging

                                • Top Differential Diagnoses

                                  • Diagnostic Checklist

                                    TERMINOLOGY

                                    • Definitions

                                      • 3 major pairs of exocrine salivary glands secrete saliva into mouth through ducts
                                        • Parotid glands
                                          • Anterior and inferior to ears
                                          • Function during meals or with thought/smell of food
                                          • Secrete saliva into mouth through parotid/Stensen duct 
                                        • Submandibular glands
                                          • Under mandible in floor of mouth
                                          • Continuously produce saliva
                                          • Secrete saliva into mouth through submandibular/Wharton/submaxillary duct 
                                        • Sublingual glands
                                          • In floor of mouth, lateral to tongue
                                          • Continuously produce saliva
                                          • Secrete saliva through ducts of Rivinus
                                      • Dysfunction can occur due to
                                        • Sjögren syndrome (autoimmune disease)
                                        • Iatrogenic
                                          • External beam radiation therapy
                                          • Radioactive iodine (I-131) therapy
                                          • Postsurgical
                                        • Sialadenitis (infection)
                                        • Sialolithiasis (stones)
                                        • Benign and malignant neoplasms

                                    IMAGING

                                    • General Features

                                      • Radiographic Findings

                                        • CT Findings

                                          • MR Findings

                                            • Ultrasonographic Findings

                                              • Nuclear Medicine Findings

                                                • Imaging Recommendations

                                                  DIFFERENTIAL DIAGNOSIS

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Treatment

                                                        DIAGNOSTIC CHECKLIST

                                                        • Consider

                                                          Selected References

                                                          1. Kaldeway HP et al: Validation of quantitative salivary gland scintigraphy in relation to the American-European concensus criteria for Sjögren's syndrome. Nucl Med Commun. 40(4):343-8, 2019
                                                          2. Afzelius P et al: Imaging of the major salivary glands. Clin Physiol Funct Imaging. 36(1):1-10, 2016
                                                          3. MacDonald A et al: Infrequently performed studies in nuclear medicine: part 2. J Nucl Med Technol. 37(1):1-13, 2009