Noncaseating granulomatous inflammatory disease of unknown etiology
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Flyger TF et al: Granulomatous inflammation in lymph nodes of the head and neck-a retrospective analysis of causes in a population with very low incidence of tuberculosis. Immunol Res. 68(4):198-203, 2020
Send T et al: Clinical features of sarcoidosis patients presenting with head and neck manifestations - a two-center retrospective study and proposal of a diagnostic algorithm for the otorhinolaryngologist. Acta Otolaryngol. 140(2):144-8, 2020
Welter SM et al: Histologic review of sarcoidosis in a neck lymph node. Head Neck Pathol. 12(2):255-8, 2018
Białek EJ et al: Mistakes in ultrasound diagnosis of superficial lymph nodes. J Ultrason. 17(68):59-65, 2017
Eisenmenger LB et al: Imaging of head and neck lymph nodes. Radiol Clin North Am. 53(1):115-32, 2015
*Holzapfel K et al: Value of diffusion-weighted MR imaging in the differentiation between benign and malignant cervical lymph nodes. Eur J Radiol. 72(3):381-7, 2008
Iannuzzi MC et al: Sarcoidosis. N Engl J Med. 357(21):2153-65, 2007
Li YJ et al: Cervical and axillary lymph node sarcoidosis misdiagnosed as lymphoma on F-18 FDG PET-CT. Clin Nucl Med. 32(3):262-4, 2007
Teirstein AS et al: Results of 188 whole-body fluorodeoxyglucose positron emission tomography scans in 137 patients with sarcoidosis. Chest. 132(6):1949-53, 2007
Saussez S et al: Clinically unsuspected tonsillar sarcoidosis in a child revealed by routine histologic examination. Int J Pediatr Otorhinolaryngol. 70(1):155-8, 2006
Porter N et al: Endocrine and reproductive manifestations of sarcoidosis. QJM. 96(8):553-61, 2003
Joe A et al: Cervical lymph node sarcoidosis as a pitfall in F-18 FDG positron emission tomography. Clin Nucl Med. 26(6):542-3, 2001
Onishi Y et al: Systemic sarcoidosis with significant granulomatous swelling of the pharyngeal tonsil. Intern Med. 37(2):157-60, 1998
Kaji AV et al: Imaging of cervical lymphadenopathy. Semin Ultrasound CT MR. 18(3):220-49, 1997
Schroder KE et al: Granulomatos cervical lymphadenitis. J Otolaryngol. 8(2):127-31, 1979
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Noncaseating granulomatous inflammatory disease of unknown etiology
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Flyger TF et al: Granulomatous inflammation in lymph nodes of the head and neck-a retrospective analysis of causes in a population with very low incidence of tuberculosis. Immunol Res. 68(4):198-203, 2020
Send T et al: Clinical features of sarcoidosis patients presenting with head and neck manifestations - a two-center retrospective study and proposal of a diagnostic algorithm for the otorhinolaryngologist. Acta Otolaryngol. 140(2):144-8, 2020
Welter SM et al: Histologic review of sarcoidosis in a neck lymph node. Head Neck Pathol. 12(2):255-8, 2018
Białek EJ et al: Mistakes in ultrasound diagnosis of superficial lymph nodes. J Ultrason. 17(68):59-65, 2017
Eisenmenger LB et al: Imaging of head and neck lymph nodes. Radiol Clin North Am. 53(1):115-32, 2015
*Holzapfel K et al: Value of diffusion-weighted MR imaging in the differentiation between benign and malignant cervical lymph nodes. Eur J Radiol. 72(3):381-7, 2008
Iannuzzi MC et al: Sarcoidosis. N Engl J Med. 357(21):2153-65, 2007
Li YJ et al: Cervical and axillary lymph node sarcoidosis misdiagnosed as lymphoma on F-18 FDG PET-CT. Clin Nucl Med. 32(3):262-4, 2007
Teirstein AS et al: Results of 188 whole-body fluorodeoxyglucose positron emission tomography scans in 137 patients with sarcoidosis. Chest. 132(6):1949-53, 2007
Saussez S et al: Clinically unsuspected tonsillar sarcoidosis in a child revealed by routine histologic examination. Int J Pediatr Otorhinolaryngol. 70(1):155-8, 2006
Porter N et al: Endocrine and reproductive manifestations of sarcoidosis. QJM. 96(8):553-61, 2003
Joe A et al: Cervical lymph node sarcoidosis as a pitfall in F-18 FDG positron emission tomography. Clin Nucl Med. 26(6):542-3, 2001
Onishi Y et al: Systemic sarcoidosis with significant granulomatous swelling of the pharyngeal tonsil. Intern Med. 37(2):157-60, 1998
Kaji AV et al: Imaging of cervical lymphadenopathy. Semin Ultrasound CT MR. 18(3):220-49, 1997
Schroder KE et al: Granulomatos cervical lymphadenitis. J Otolaryngol. 8(2):127-31, 1979
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