Bookmarks
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Neurosarcoidosis
Definitions
- Noncaseating granulomatous disease of spine and spinal cord
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Murphy OC et al: Clinical and MRI phenotypes of sarcoidosis-associated myelopathy. Neurol Neuroimmunol Neuroinflamm. 7(4):e722, 2020
- Ben Hassine I et al: Osseous sarcoidosis: a multicenter retrospective case-control study of 48 patients. Joint Bone Spine. 86(6):789-93, 2019
- Sigaux J et al: High prevalence of spondyloarthritis in sarcoidosis patients with chronic back pain. Semin Arthritis Rheum. 49(2):246-50, 2019
- Soni N et al: Imaging findings in spinal sarcoidosis: a report of 18 cases and review of the current literature. Neuroradiol J. 32(1):17-28, 2019
- Sohn M et al: Spinal cord neurosarcoidosis. Am J Med Sci. 347(3):195-8, 2014
- Nozaki K et al: Neurosarcoidosis. Curr Treat Options Neurol. 15(4):492-504, 2013
- Brembilla C et al: Surgical management in spinal sarcoidosis: case report. Spine (Phila Pa 1976). 34(7):E258-61, 2009
- Makino T et al: Diffuse neurosarcoidosis involving only the leptomeninges of the brainstem and spinal cord. Intern Med. 48(21):1909-13, 2009
- Varron L et al: Spinal cord sarcoidosis: report of seven cases. Eur J Neurol. 16(3):289-96, 2009
- Beros V et al: Thoracic intramedullary sarcoidosis mimicking an intramedullary tumor. Coll Antropol. 32(2):645-7, 2008
- Boulaajaj FZ et al: [Subacute myelopathy revealing systemic sarcoidosis.] Rev Neurol (Paris). 163(11):1049-53, 2007
- Perdigão S et al: [Atypical presentation of intramedullary sarcoidosis: report of two cases.] Rev Neurol. 45(7):406-8, 2007
- Ravaglia S et al: Pathogenetic role of myelitis for syringomyelia. Clin Neurol Neurosurg. 109(6):541-6, 2007
- Schaller B et al: Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature. Spine J. 6(2):204-10, 2006
- Smith JK et al: Imaging manifestations of neurosarcoidosis. AJR Am J Roentgenol. 182(2):289-95, 2004
- Bose B: Extramedullary sarcoid lesion mimicking intraspinal tumor. Spine J. 2(5):381-5, 2002
- Dubey N et al: Role of fluorodeoxyglucose positron emission tomography in the diagnosis of neurosarcoidosis. J Neurol Sci. 205(1):77-81, 2002
- Gullapalli D et al: Neurologic manifestations of sarcoidosis. Neurol Clin. 20(1):59-83, vi, 2002
- Bode MK et al: Isolated neurosarcoidosis - MR findings and pathologic correlation. Acta Radiol. 42(6):563-7, 2001
- Hayat GR et al: Solitary intramedullary neurosarcoidosis: role of MRI in early detection. J Neuroimaging. 11(1):66-70, 2001
- Maroun FB et al: Sarcoidosis presenting as an intramedullary spinal cord lesion. Can J Neurol Sci. 28(2):163-6, 2001
- Vinas FC et al: Spinal cord sarcoidosis: a diagnostic dilemma. Neurol Res. 23(4):347-52, 2001
- Dumas JL et al: Central nervous system sarcoidosis: follow-up at MR imaging during steroid therapy. Radiology. 214(2):411-20, 2000
- Koike H et al: Differential response to corticosteroid therapy of MRI findings and clinical manifestations in spinal cord sarcoidosis. J Neurol. 247(7):544-9, 2000
- Yasui K et al: Correlation of magnetic resonance imaging findings and histopathology of lesion distribution of spinal cord sarcoidosis at post-mortem. Neuropathol Appl Neurobiol. 26(5):481-7, 2000
- Christoforidis GA et al: MR of CNS sarcoidosis: correlation of imaging features to clinical symptoms and response to treatment. AJNR Am J Neuroradiol. 20(4):655-69, 1999
- Hashmi M et al: Diagnosis and treatment of intramedullary spinal cord sarcoidosis. J Neurol. 245(3):178-80, 1998
- Jallo GI et al: Intraspinal sarcoidosis: diagnosis and management. Surg Neurol. 48(5):514-20; discussion 521, 1997
- Lexa FJ et al: MR of sarcoidosis in the head and spine: spectrum of manifestations and radiographic response to steroid therapy. AJNR Am J Neuroradiol. 15(5):973-82, 1994
- Junger SS et al: Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics. Neurology. 43(2):333-7, 1993
- Seltzer S et al: CNS sarcoidosis: evaluation with contrast-enhanced MR imaging. AJNR Am J Neuroradiol. 12(6):1227-33, 1991
- Nesbit GM et al: Spinal cord sarcoidosis: a new finding at MR imaging with Gd-DTPA enhancement. Radiology. 173(3):839-43, 1989
- Terunuma H et al: Sarcoidosis presenting as progressive myelopathy. Clin Neuropathol. 7(2):77-80, 1988
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Neurosarcoidosis
Definitions
- Noncaseating granulomatous disease of spine and spinal cord
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Murphy OC et al: Clinical and MRI phenotypes of sarcoidosis-associated myelopathy. Neurol Neuroimmunol Neuroinflamm. 7(4):e722, 2020
- Ben Hassine I et al: Osseous sarcoidosis: a multicenter retrospective case-control study of 48 patients. Joint Bone Spine. 86(6):789-93, 2019
- Sigaux J et al: High prevalence of spondyloarthritis in sarcoidosis patients with chronic back pain. Semin Arthritis Rheum. 49(2):246-50, 2019
- Soni N et al: Imaging findings in spinal sarcoidosis: a report of 18 cases and review of the current literature. Neuroradiol J. 32(1):17-28, 2019
- Sohn M et al: Spinal cord neurosarcoidosis. Am J Med Sci. 347(3):195-8, 2014
- Nozaki K et al: Neurosarcoidosis. Curr Treat Options Neurol. 15(4):492-504, 2013
- Brembilla C et al: Surgical management in spinal sarcoidosis: case report. Spine (Phila Pa 1976). 34(7):E258-61, 2009
- Makino T et al: Diffuse neurosarcoidosis involving only the leptomeninges of the brainstem and spinal cord. Intern Med. 48(21):1909-13, 2009
- Varron L et al: Spinal cord sarcoidosis: report of seven cases. Eur J Neurol. 16(3):289-96, 2009
- Beros V et al: Thoracic intramedullary sarcoidosis mimicking an intramedullary tumor. Coll Antropol. 32(2):645-7, 2008
- Boulaajaj FZ et al: [Subacute myelopathy revealing systemic sarcoidosis.] Rev Neurol (Paris). 163(11):1049-53, 2007
- Perdigão S et al: [Atypical presentation of intramedullary sarcoidosis: report of two cases.] Rev Neurol. 45(7):406-8, 2007
- Ravaglia S et al: Pathogenetic role of myelitis for syringomyelia. Clin Neurol Neurosurg. 109(6):541-6, 2007
- Schaller B et al: Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature. Spine J. 6(2):204-10, 2006
- Smith JK et al: Imaging manifestations of neurosarcoidosis. AJR Am J Roentgenol. 182(2):289-95, 2004
- Bose B: Extramedullary sarcoid lesion mimicking intraspinal tumor. Spine J. 2(5):381-5, 2002
- Dubey N et al: Role of fluorodeoxyglucose positron emission tomography in the diagnosis of neurosarcoidosis. J Neurol Sci. 205(1):77-81, 2002
- Gullapalli D et al: Neurologic manifestations of sarcoidosis. Neurol Clin. 20(1):59-83, vi, 2002
- Bode MK et al: Isolated neurosarcoidosis - MR findings and pathologic correlation. Acta Radiol. 42(6):563-7, 2001
- Hayat GR et al: Solitary intramedullary neurosarcoidosis: role of MRI in early detection. J Neuroimaging. 11(1):66-70, 2001
- Maroun FB et al: Sarcoidosis presenting as an intramedullary spinal cord lesion. Can J Neurol Sci. 28(2):163-6, 2001
- Vinas FC et al: Spinal cord sarcoidosis: a diagnostic dilemma. Neurol Res. 23(4):347-52, 2001
- Dumas JL et al: Central nervous system sarcoidosis: follow-up at MR imaging during steroid therapy. Radiology. 214(2):411-20, 2000
- Koike H et al: Differential response to corticosteroid therapy of MRI findings and clinical manifestations in spinal cord sarcoidosis. J Neurol. 247(7):544-9, 2000
- Yasui K et al: Correlation of magnetic resonance imaging findings and histopathology of lesion distribution of spinal cord sarcoidosis at post-mortem. Neuropathol Appl Neurobiol. 26(5):481-7, 2000
- Christoforidis GA et al: MR of CNS sarcoidosis: correlation of imaging features to clinical symptoms and response to treatment. AJNR Am J Neuroradiol. 20(4):655-69, 1999
- Hashmi M et al: Diagnosis and treatment of intramedullary spinal cord sarcoidosis. J Neurol. 245(3):178-80, 1998
- Jallo GI et al: Intraspinal sarcoidosis: diagnosis and management. Surg Neurol. 48(5):514-20; discussion 521, 1997
- Lexa FJ et al: MR of sarcoidosis in the head and spine: spectrum of manifestations and radiographic response to steroid therapy. AJNR Am J Neuroradiol. 15(5):973-82, 1994
- Junger SS et al: Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics. Neurology. 43(2):333-7, 1993
- Seltzer S et al: CNS sarcoidosis: evaluation with contrast-enhanced MR imaging. AJNR Am J Neuroradiol. 12(6):1227-33, 1991
- Nesbit GM et al: Spinal cord sarcoidosis: a new finding at MR imaging with Gd-DTPA enhancement. Radiology. 173(3):839-43, 1989
- Terunuma H et al: Sarcoidosis presenting as progressive myelopathy. Clin Neuropathol. 7(2):77-80, 1988
