Malignant mesenchymal neoplasms arising from connective tissue elements of breast, including AS, MFH, pleomorphic spindle cell sarcoma, liposarcoma, leiomyosarcoma, and MFH
IMAGING
General Features
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
Duncan MA et al: Sarcomas of the breast. Surg Clin North Am. 98(4):869-876, 2018
Feinberg L et al: Impact of specialist management on survival from radiation-associated angiosarcoma of the breast. Br J Surg. 105(4):401-409, 2018
Hatta N et al: Undifferentiated pleomorphic sarcoma in a patient with Cowden syndrome after radiotherapy for breast cancer. J Dermatol. ePub, 2018
Kunkiel M et al: Primary angiosarcoma of the breast-series of 11 consecutive cases-a single-centre experience. Curr Oncol. 25(1):e50-e53, 2018
Salminen SH et al: Radiation-associated sarcoma after breast cancer in a nationwide population: Increasing risk of angiosarcoma. Cancer Med. ePub, 2018
Whorms DS et al: Mesenchymal Lesions of the Breast: What Radiologists Need to Know. AJR Am J Roentgenol. 211(1):224-233, 2018
Singh G et al: Primary Leiomyosarcoma of Breast Presenting with Metastasis: An Atypical Presentation with Dismal Prognosis. Indian J Med Paediatr Oncol. 38(4):535-537, 2017
Holm M et al: Primary breast sarcoma: A retrospective study over 35 years from a single institution. Acta Oncol. 55(5):584-90, 2016
Lim SZ et al: Sarcoma of the breast: an update on a rare entity. J Clin Pathol. 69(5):373-81, 2016
Yin M et al: Primary female breast sarcoma: clinicopathological features, treatment and prognosis. Sci Rep. 6:31497, 2016
Chikarmane SA et al: MRI findings of radiation-associated angiosarcoma of the breast (RAS). J Magn Reson Imaging. 42(3):763-70, 2015
Wang F et al: Comparison of the clinical and prognostic features of primary breast sarcomas and malignant phyllodes tumor. Jpn J Clin Oncol. 45(2):146-52, 2015
Smith TB et al: Imaging features of primary breast sarcoma. AJR Am J Roentgenol. 198(4):W386-93, 2012
Tan H et al: Imaging findings in phyllodes tumors of the breast. Eur J Radiol. 81(1):e62-9, 2012
Surov A et al: Primary breast sarcoma: prevalence, clinical signs, and radiological features. Acta Radiol. 52(6):597-601, 2011
SantamarĂa G et al: Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 30(2):533-48, 2010
Glazebrook KN et al: Angiosarcoma of the breast. AJR Am J Roentgenol. 190(2):533-8, 2008
Lvoff NM et al: Case of the season: primary angiosarcoma of the breast: correlative imaging and pathology. Semin Roentgenol. 42(4):208-10, 2007
Yang WT et al: Imaging differences in metaplastic and invasive ductal carcinomas of the breast. AJR Am J Roentgenol. 189(6):1288-93, 2007
Yang WT et al: Mammary angiosarcomas: imaging findings in 24 patients. Radiology. 242(3):725-34, 2007
Adem C et al: Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. Br J Cancer. 91(2):237-41, 2004
Barrow BJ et al: Role of radiotherapy in sarcoma of the breast--a retrospective review of the M.D. Anderson experience. Radiother Oncol. 52(2):173-8, 1999
Gutman H et al: Sarcoma of the breast: implications for extent of therapy. The M. D. Anderson experience. Surgery. 116(3):505-9, 1994
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Angiosarcoma (AS)
Malignant fibrous histiocytoma (MFH)
Definitions
Malignant mesenchymal neoplasms arising from connective tissue elements of breast, including AS, MFH, pleomorphic spindle cell sarcoma, liposarcoma, leiomyosarcoma, and MFH
IMAGING
General Features
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
Selected References
Duncan MA et al: Sarcomas of the breast. Surg Clin North Am. 98(4):869-876, 2018
Feinberg L et al: Impact of specialist management on survival from radiation-associated angiosarcoma of the breast. Br J Surg. 105(4):401-409, 2018
Hatta N et al: Undifferentiated pleomorphic sarcoma in a patient with Cowden syndrome after radiotherapy for breast cancer. J Dermatol. ePub, 2018
Kunkiel M et al: Primary angiosarcoma of the breast-series of 11 consecutive cases-a single-centre experience. Curr Oncol. 25(1):e50-e53, 2018
Salminen SH et al: Radiation-associated sarcoma after breast cancer in a nationwide population: Increasing risk of angiosarcoma. Cancer Med. ePub, 2018
Whorms DS et al: Mesenchymal Lesions of the Breast: What Radiologists Need to Know. AJR Am J Roentgenol. 211(1):224-233, 2018
Singh G et al: Primary Leiomyosarcoma of Breast Presenting with Metastasis: An Atypical Presentation with Dismal Prognosis. Indian J Med Paediatr Oncol. 38(4):535-537, 2017
Holm M et al: Primary breast sarcoma: A retrospective study over 35 years from a single institution. Acta Oncol. 55(5):584-90, 2016
Lim SZ et al: Sarcoma of the breast: an update on a rare entity. J Clin Pathol. 69(5):373-81, 2016
Yin M et al: Primary female breast sarcoma: clinicopathological features, treatment and prognosis. Sci Rep. 6:31497, 2016
Chikarmane SA et al: MRI findings of radiation-associated angiosarcoma of the breast (RAS). J Magn Reson Imaging. 42(3):763-70, 2015
Wang F et al: Comparison of the clinical and prognostic features of primary breast sarcomas and malignant phyllodes tumor. Jpn J Clin Oncol. 45(2):146-52, 2015
Smith TB et al: Imaging features of primary breast sarcoma. AJR Am J Roentgenol. 198(4):W386-93, 2012
Tan H et al: Imaging findings in phyllodes tumors of the breast. Eur J Radiol. 81(1):e62-9, 2012
Surov A et al: Primary breast sarcoma: prevalence, clinical signs, and radiological features. Acta Radiol. 52(6):597-601, 2011
SantamarĂa G et al: Radiologic and pathologic findings in breast tumors with high signal intensity on T2-weighted MR images. Radiographics. 30(2):533-48, 2010
Glazebrook KN et al: Angiosarcoma of the breast. AJR Am J Roentgenol. 190(2):533-8, 2008
Lvoff NM et al: Case of the season: primary angiosarcoma of the breast: correlative imaging and pathology. Semin Roentgenol. 42(4):208-10, 2007
Yang WT et al: Imaging differences in metaplastic and invasive ductal carcinomas of the breast. AJR Am J Roentgenol. 189(6):1288-93, 2007
Yang WT et al: Mammary angiosarcomas: imaging findings in 24 patients. Radiology. 242(3):725-34, 2007
Adem C et al: Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature. Br J Cancer. 91(2):237-41, 2004
Barrow BJ et al: Role of radiotherapy in sarcoma of the breast--a retrospective review of the M.D. Anderson experience. Radiother Oncol. 52(2):173-8, 1999
Gutman H et al: Sarcoma of the breast: implications for extent of therapy. The M. D. Anderson experience. Surgery. 116(3):505-9, 1994
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