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Schwannoma
Terrance Healey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Neurilemmoma
              • Definitions

                • Peripheral nerve sheath tumor (PNST)

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Kapoor A et al: Mediastinal schwannoma: A clinical, pathologic, and imaging review. South Asian J Cancer. 4(2):104-5, 2015
                                          2. Shin KE et al: Diffusion-weighted MRI for distinguishing non-neoplastic cysts from solid masses in the mediastinum: problem-solving in mediastinal masses of indeterminate internal characteristics on CT. Eur Radiol. 24(3):677-84, 2014
                                          3. Abreu E et al: Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol. Epub ahead of print, 2011
                                          4. Koontz NA et al: Schwannomatosis: the overlooked neurofibromatosis? AJR Am J Roentgenol. 200(6):W646-53, 2013
                                          5. Gerszten PC et al: Radiosurgery for benign tumors of the spine using the Synergy S with cone-beam computed tomography image guidance. J Neurosurg. 117 Suppl:197-202, 2012
                                          6. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                          7. Woertler K: Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol. 14(5):547-58, 2010
                                          8. Spitzer AL et al: Anatomic classification system for surgical management of paraspinal tumors. Arch Surg. 139(3):262-9, 2004
                                          9. Takeda S et al: Intrathoracic neurogenic tumors--50 years' experience in a Japanese institution. Eur J Cardiothorac Surg. 26(4):807-12, 2004
                                          10. Cardona S et al: Evaluation of F18-deoxyglucose positron emission tomography (FDG-PET) to assess the nature of neurogenic tumours. Eur J Surg Oncol. 29(6):536-41, 2003
                                          11. Erasmus JJ et al: MR imaging of mediastinal masses. Magn Reson Imaging Clin N Am. 8(1):59-89, 2000
                                          12. Reeder LB: Neurogenic tumors of the mediastinum. Semin Thorac Cardiovasc Surg. 12(4):261-7, 2000
                                          13. Lee JY et al: Spectrum of neurogenic tumors in the thorax: CT and pathologic findings. J Comput Assist Tomogr. 23(3):399-406, 1999
                                          14. Marchevsky AM: Mediastinal tumors of peripheral nervous system origin. Semin Diagn Pathol. 16(1):65-78, 1999
                                          15. Strollo DC et al: Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 112(5):1344-57, 1997
                                          16. Sakai F et al: Intrathoracic neurogenic tumors: MR-pathologic correlation. AJR Am J Roentgenol. 159(2):279-83, 1992
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Neurilemmoma
                                                      • Definitions

                                                        • Peripheral nerve sheath tumor (PNST)

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Kapoor A et al: Mediastinal schwannoma: A clinical, pathologic, and imaging review. South Asian J Cancer. 4(2):104-5, 2015
                                                                                  2. Shin KE et al: Diffusion-weighted MRI for distinguishing non-neoplastic cysts from solid masses in the mediastinum: problem-solving in mediastinal masses of indeterminate internal characteristics on CT. Eur Radiol. 24(3):677-84, 2014
                                                                                  3. Abreu E et al: Peripheral tumor and tumor-like neurogenic lesions. Eur J Radiol. Epub ahead of print, 2011
                                                                                  4. Koontz NA et al: Schwannomatosis: the overlooked neurofibromatosis? AJR Am J Roentgenol. 200(6):W646-53, 2013
                                                                                  5. Gerszten PC et al: Radiosurgery for benign tumors of the spine using the Synergy S with cone-beam computed tomography image guidance. J Neurosurg. 117 Suppl:197-202, 2012
                                                                                  6. Nam SJ et al: Imaging of primary chest wall tumors with radiologic-pathologic correlation. Radiographics. 31(3):749-70, 2011
                                                                                  7. Woertler K: Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol. 14(5):547-58, 2010
                                                                                  8. Spitzer AL et al: Anatomic classification system for surgical management of paraspinal tumors. Arch Surg. 139(3):262-9, 2004
                                                                                  9. Takeda S et al: Intrathoracic neurogenic tumors--50 years' experience in a Japanese institution. Eur J Cardiothorac Surg. 26(4):807-12, 2004
                                                                                  10. Cardona S et al: Evaluation of F18-deoxyglucose positron emission tomography (FDG-PET) to assess the nature of neurogenic tumours. Eur J Surg Oncol. 29(6):536-41, 2003
                                                                                  11. Erasmus JJ et al: MR imaging of mediastinal masses. Magn Reson Imaging Clin N Am. 8(1):59-89, 2000
                                                                                  12. Reeder LB: Neurogenic tumors of the mediastinum. Semin Thorac Cardiovasc Surg. 12(4):261-7, 2000
                                                                                  13. Lee JY et al: Spectrum of neurogenic tumors in the thorax: CT and pathologic findings. J Comput Assist Tomogr. 23(3):399-406, 1999
                                                                                  14. Marchevsky AM: Mediastinal tumors of peripheral nervous system origin. Semin Diagn Pathol. 16(1):65-78, 1999
                                                                                  15. Strollo DC et al: Primary mediastinal tumors: part II. Tumors of the middle and posterior mediastinum. Chest. 112(5):1344-57, 1997
                                                                                  16. Sakai F et al: Intrathoracic neurogenic tumors: MR-pathologic correlation. AJR Am J Roentgenol. 159(2):279-83, 1992