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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Neurofibromatosis type 2 (NF2)
- Multiple inherited schwannomas, meningiomas, and ependymomas (MISME)
- Neurofibromatosis type 2 (NF2)
Synonyms
- Neurinoma, neurilemmoma (outdated terms)
- Nerve sheath tumor (NST)
Definitions
- Neoplasm of nerve sheath (Schwann cells)
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Tish S et al: The epidemiology of spinal schwannoma in the United States between 2006 and 2014. J Neurosurg Spine. 1-6, 2019
- Ardern-Holmes S et al: Neurofibromatosis type 2. J Child Neurol. 32(1):9-22, 2017
- Gu BS et al: Surgical strategies for removal of intra- and extraforaminal dumbbell-shaped schwannomas in the subaxial cervical spine. Eur Spine J. 24(10):2114-8, 2015
- Kukreja S et al: Cauda equina schwannoma presenting with intratumoral hemorrhage and intracranial subarachnoid hemorrhage. J Neurosurg Spine. 21(3):357-60, 2014
- Netra R et al: Spinal cystic schwannoma: an MRI evaluation. J Coll Physicians Surg Pak. 24(2):145-7, 2014
- Vadivelu S et al: Giant invasive spinal schwannoma in children: a case report and review of the literature. J Med Case Rep. 7:289, 2013
- Murovic JA et al: Foraminal nerve sheath tumors: intermediate follow-up after cyberknife radiosurgery. Neurosurgery. 64(2 Suppl):A33-43, 2009
- Ozawa H et al: Spinal dumbbell tumors: an analysis of a series of 118 cases. J Neurosurg Spine. 7(6):587-93, 2007
- Dodd RL et al: CyberKnife radiosurgery for benign intradural extramedullary spinal tumors. Neurosurgery. 58(4):674-85; discussion 674-85, 2006
- Conti P et al: Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature. Surg Neurol. 61(1):34-43; discussion 44, 2004
- Colosimo C et al: Magnetic resonance imaging of intramedullary spinal cord schwannomas. Report of two cases and review of the literature. J Neurosurg. 99(1 Suppl):114-7, 2003
- Hasegawa M et al: Surgical pathology of spinal schwannomas: a light and electron microscopic analysis of tumor capsules. Neurosurgery. 49(6):1388-92; discussion 1392-3, 2001
- Sridhar K et al: Giant invasive spinal schwannomas: definition and surgical management. J Neurosurg. 94(2 Suppl):210-5, 2001
- Woodruff JM et al: Schwannoma. In Kleihues P et al: Tumors of the Nervous System. Lyon: IARC Press. 164-6, 2000
- Murphey MD et al: From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 19(5):1253-80, 1999
- Vallat-Decouvelaere AV et al: Spinal melanotic schwannoma: a tumour with poor prognosis. Histopathology. 35(6):558-66, 1999
- Mautner VF et al: Spinal tumors in patients with neurofibromatosis type 2: MR imaging study of frequency, multiplicity, and variety. AJR Am J Roentgenol. 165(4):951-5, 1995
- Akeson P et al: Radiological investigation of neurofibromatosis type 2. Neuroradiology. 36(2):107-10, 1994
- Matsumoto S et al: MRI of intradural-extramedullary spinal neurinomas and meningiomas. Clin Imaging. 17(1):46-52, 1993
- Friedman DP et al: Intradural schwannomas of the spine: MR findings with emphasis on contrast-enhancement characteristics. AJR Am J Roentgenol. 158(6):1347-50, 1992
- Shen WC et al: Cystic spinal neurilemmoma on magnetic resonance imaging. Neuroradiology. 34(5):447-8, 1992
- Demachi H et al: MR imaging of spinal neurinomas with pathological correlation. J Comput Assist Tomogr. 14(2):250-4, 1990
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Neurofibromatosis type 2 (NF2)
- Multiple inherited schwannomas, meningiomas, and ependymomas (MISME)
- Neurofibromatosis type 2 (NF2)
Synonyms
- Neurinoma, neurilemmoma (outdated terms)
- Nerve sheath tumor (NST)
Definitions
- Neoplasm of nerve sheath (Schwann cells)
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
- Tish S et al: The epidemiology of spinal schwannoma in the United States between 2006 and 2014. J Neurosurg Spine. 1-6, 2019
- Ardern-Holmes S et al: Neurofibromatosis type 2. J Child Neurol. 32(1):9-22, 2017
- Gu BS et al: Surgical strategies for removal of intra- and extraforaminal dumbbell-shaped schwannomas in the subaxial cervical spine. Eur Spine J. 24(10):2114-8, 2015
- Kukreja S et al: Cauda equina schwannoma presenting with intratumoral hemorrhage and intracranial subarachnoid hemorrhage. J Neurosurg Spine. 21(3):357-60, 2014
- Netra R et al: Spinal cystic schwannoma: an MRI evaluation. J Coll Physicians Surg Pak. 24(2):145-7, 2014
- Vadivelu S et al: Giant invasive spinal schwannoma in children: a case report and review of the literature. J Med Case Rep. 7:289, 2013
- Murovic JA et al: Foraminal nerve sheath tumors: intermediate follow-up after cyberknife radiosurgery. Neurosurgery. 64(2 Suppl):A33-43, 2009
- Ozawa H et al: Spinal dumbbell tumors: an analysis of a series of 118 cases. J Neurosurg Spine. 7(6):587-93, 2007
- Dodd RL et al: CyberKnife radiosurgery for benign intradural extramedullary spinal tumors. Neurosurgery. 58(4):674-85; discussion 674-85, 2006
- Conti P et al: Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature. Surg Neurol. 61(1):34-43; discussion 44, 2004
- Colosimo C et al: Magnetic resonance imaging of intramedullary spinal cord schwannomas. Report of two cases and review of the literature. J Neurosurg. 99(1 Suppl):114-7, 2003
- Hasegawa M et al: Surgical pathology of spinal schwannomas: a light and electron microscopic analysis of tumor capsules. Neurosurgery. 49(6):1388-92; discussion 1392-3, 2001
- Sridhar K et al: Giant invasive spinal schwannomas: definition and surgical management. J Neurosurg. 94(2 Suppl):210-5, 2001
- Woodruff JM et al: Schwannoma. In Kleihues P et al: Tumors of the Nervous System. Lyon: IARC Press. 164-6, 2000
- Murphey MD et al: From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 19(5):1253-80, 1999
- Vallat-Decouvelaere AV et al: Spinal melanotic schwannoma: a tumour with poor prognosis. Histopathology. 35(6):558-66, 1999
- Mautner VF et al: Spinal tumors in patients with neurofibromatosis type 2: MR imaging study of frequency, multiplicity, and variety. AJR Am J Roentgenol. 165(4):951-5, 1995
- Akeson P et al: Radiological investigation of neurofibromatosis type 2. Neuroradiology. 36(2):107-10, 1994
- Matsumoto S et al: MRI of intradural-extramedullary spinal neurinomas and meningiomas. Clin Imaging. 17(1):46-52, 1993
- Friedman DP et al: Intradural schwannomas of the spine: MR findings with emphasis on contrast-enhancement characteristics. AJR Am J Roentgenol. 158(6):1347-50, 1992
- Shen WC et al: Cystic spinal neurilemmoma on magnetic resonance imaging. Neuroradiology. 34(5):447-8, 1992
- Demachi H et al: MR imaging of spinal neurinomas with pathological correlation. J Comput Assist Tomogr. 14(2):250-4, 1990
