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Sclerosing Mesenteritis
Siva P. Raman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Retractile mesenteritis, fibrosing mesenteritis, mesenteric panniculitis, mesenteric lipodystrophy, liposclerotic mesenteritis, systemic nodular panniculitis, xanthogranulomatous mesenteritis
            • Definitions

              • Idiopathic inflammatory and fibrotic disorder of unknown etiology affecting mesentery

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Radiographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Wang J et al: Getting to the root of the problem. Gastroenterology. 158(5):1229-31, 2020
                                            2. Buragina G et al: Clinical and radiological features of mesenteric panniculitis: a critical overview. Acta Biomed. 90(4):411-22, 2019
                                            3. Kumar P et al: Demystifying the mesenteric root lesions. Abdom Radiol (NY). 44(8):2708-20, 2019
                                            4. Fu Z et al: 18F-FDG PET/CT Findings in a patient with IgG4-related sclerosing mesenteritis. Clin Nucl Med. 43(4):294-5, 2018
                                            5. Gögebakan Ö et al: Mesenteric panniculitis (MP): a frequent coincidental CT finding of debatable clinical significance. Rofo. 190(11):1044-52, 2018
                                            6. Halligan S et al: Mesenteric panniculitis: systematic review of cross-sectional imaging findings and risk of subsequent malignancy. Eur Radiol. 26(12):4531-7, 2016
                                            7. Wasnik AP et al: Primary and secondary disease of the peritoneum and mesentery: review of anatomy and imaging features. Abdom Imaging. 40(3):626-42, 2015
                                            8. van Putte-Katier N et al: Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up. Br J Radiol. 87(1044):20140451, 2014
                                            9. McLaughlin PD et al: The "misty mesentery": mesenteric panniculitis and its mimics. AJR Am J Roentgenol. 200(2):W116-23, 2013
                                            10. Canyigit M et al: Multidetector-row computed tomography findings of sclerosing mesenteritis with associated diseases and its prevalence. Jpn J Radiol. 29(7):495-502, 2011
                                            11. Coulier B: Mesenteric panniculitis. Part 1: MDCT--pictorial review. JBR-BTR. 94(5):229-40, 2011
                                            12. Scudiere JR et al: Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer. Am J Surg Pathol. 34(4):447-53, 2010
                                            13. Arora M et al: A clinical case study: sclerosing mesenteritis presenting as chylous ascites. Medscape J Med. 10(2):30, 2008
                                            14. Chen TS et al: Are tumefactive lesions classified as sclerosing mesenteritis a subset of IgG4-related sclerosing disorders? J Clin Pathol. 61(10):1093-7, 2008
                                            15. Preda M et al: Sclerosing mesenteritis presenting with abdominal pain and fever in a young woman: computed tomography findings. ANZ J Surg. 78(8):709-10, 2008
                                            16. Akram S et al: Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients. Clin Gastroenterol Hepatol. 5(5):589-96; quiz 523-4, 2007
                                            17. Levy AD et al: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics. 26(1):245-64, 2006
                                            18. Matsuki M et al: CT and MR features of sclerosing mesenteritis mimicking a mesenteric metastasis from the carcinoid tumor. Radiat Med. 24(3):220-3, 2006
                                            19. Zissin R et al: Mesenteric panniculitis in oncologic patients: PET-CT findings. Br J Radiol. 79(937):37-43, 2006
                                            20. Horton KM et al: CT findings in sclerosing mesenteritis (panniculitis): spectrum of disease. Radiographics. 23(6): 1561-7, 2003
                                            21. Nguyen BD: F-18 FDG PET demonstration of sclerosing mesenteritis. Clin Nucl Med. 28(8):670-1, 2003
                                            22. Seo BK et al: Segmental misty mesentery: analysis of CT features and primary causes. Radiology. 226(1): 86-94, 2003
                                            23. Mindelzun RE et al: The misty mesentery on CT: differential diagnosis. AJR Am J Roentgenol. 167(1): 61-5, 1996
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Retractile mesenteritis, fibrosing mesenteritis, mesenteric panniculitis, mesenteric lipodystrophy, liposclerotic mesenteritis, systemic nodular panniculitis, xanthogranulomatous mesenteritis
                                                      • Definitions

                                                        • Idiopathic inflammatory and fibrotic disorder of unknown etiology affecting mesentery

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Nuclear Medicine Findings

                                                              • Radiographic Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Wang J et al: Getting to the root of the problem. Gastroenterology. 158(5):1229-31, 2020
                                                                                      2. Buragina G et al: Clinical and radiological features of mesenteric panniculitis: a critical overview. Acta Biomed. 90(4):411-22, 2019
                                                                                      3. Kumar P et al: Demystifying the mesenteric root lesions. Abdom Radiol (NY). 44(8):2708-20, 2019
                                                                                      4. Fu Z et al: 18F-FDG PET/CT Findings in a patient with IgG4-related sclerosing mesenteritis. Clin Nucl Med. 43(4):294-5, 2018
                                                                                      5. Gögebakan Ö et al: Mesenteric panniculitis (MP): a frequent coincidental CT finding of debatable clinical significance. Rofo. 190(11):1044-52, 2018
                                                                                      6. Halligan S et al: Mesenteric panniculitis: systematic review of cross-sectional imaging findings and risk of subsequent malignancy. Eur Radiol. 26(12):4531-7, 2016
                                                                                      7. Wasnik AP et al: Primary and secondary disease of the peritoneum and mesentery: review of anatomy and imaging features. Abdom Imaging. 40(3):626-42, 2015
                                                                                      8. van Putte-Katier N et al: Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up. Br J Radiol. 87(1044):20140451, 2014
                                                                                      9. McLaughlin PD et al: The "misty mesentery": mesenteric panniculitis and its mimics. AJR Am J Roentgenol. 200(2):W116-23, 2013
                                                                                      10. Canyigit M et al: Multidetector-row computed tomography findings of sclerosing mesenteritis with associated diseases and its prevalence. Jpn J Radiol. 29(7):495-502, 2011
                                                                                      11. Coulier B: Mesenteric panniculitis. Part 1: MDCT--pictorial review. JBR-BTR. 94(5):229-40, 2011
                                                                                      12. Scudiere JR et al: Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer. Am J Surg Pathol. 34(4):447-53, 2010
                                                                                      13. Arora M et al: A clinical case study: sclerosing mesenteritis presenting as chylous ascites. Medscape J Med. 10(2):30, 2008
                                                                                      14. Chen TS et al: Are tumefactive lesions classified as sclerosing mesenteritis a subset of IgG4-related sclerosing disorders? J Clin Pathol. 61(10):1093-7, 2008
                                                                                      15. Preda M et al: Sclerosing mesenteritis presenting with abdominal pain and fever in a young woman: computed tomography findings. ANZ J Surg. 78(8):709-10, 2008
                                                                                      16. Akram S et al: Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients. Clin Gastroenterol Hepatol. 5(5):589-96; quiz 523-4, 2007
                                                                                      17. Levy AD et al: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics. 26(1):245-64, 2006
                                                                                      18. Matsuki M et al: CT and MR features of sclerosing mesenteritis mimicking a mesenteric metastasis from the carcinoid tumor. Radiat Med. 24(3):220-3, 2006
                                                                                      19. Zissin R et al: Mesenteric panniculitis in oncologic patients: PET-CT findings. Br J Radiol. 79(937):37-43, 2006
                                                                                      20. Horton KM et al: CT findings in sclerosing mesenteritis (panniculitis): spectrum of disease. Radiographics. 23(6): 1561-7, 2003
                                                                                      21. Nguyen BD: F-18 FDG PET demonstration of sclerosing mesenteritis. Clin Nucl Med. 28(8):670-1, 2003
                                                                                      22. Seo BK et al: Segmental misty mesentery: analysis of CT features and primary causes. Radiology. 226(1): 86-94, 2003
                                                                                      23. Mindelzun RE et al: The misty mesentery on CT: differential diagnosis. AJR Am J Roentgenol. 167(1): 61-5, 1996