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KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Abbreviations
- Osteosarcoma (OS)
Synonyms
- Paget sarcoma
- Radiation sarcoma, post-radiation sarcoma
- Dedifferentiated chondrosarcoma
- Dedifferentiated sarcoma
Definitions
- Bone-forming sarcoma arising in bone affected by underlying condition making it susceptible to sarcomatous degeneration
- Paget disease
- Previously radiated bone
- Dedifferentiated chondrosarcoma
- Other rare disorders, including dedifferentiation of surface osteosarcomas (OS) to high-grade OS
- Bone-forming sarcoma arising in bone affected by underlying condition making it susceptible to sarcomatous degeneration
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Forest M et al: Secondary osteosarcomas. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone. Lyon: IARC Press. 277-8, 2002
- Yagishita S et al: Secondary osteosarcoma developing 10 years after chemoradiotherapy for non-small-cell lung cancer. Jpn J Clin Oncol. 44(2):191-4, 2014
- Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Abbreviations
- Osteosarcoma (OS)
Synonyms
- Paget sarcoma
- Radiation sarcoma, post-radiation sarcoma
- Dedifferentiated chondrosarcoma
- Dedifferentiated sarcoma
Definitions
- Bone-forming sarcoma arising in bone affected by underlying condition making it susceptible to sarcomatous degeneration
- Paget disease
- Previously radiated bone
- Dedifferentiated chondrosarcoma
- Other rare disorders, including dedifferentiation of surface osteosarcomas (OS) to high-grade OS
- Bone-forming sarcoma arising in bone affected by underlying condition making it susceptible to sarcomatous degeneration
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Forest M et al: Secondary osteosarcomas. In Fletcher CDM et al: World Health Organization Classification of Tumours: Tumours of Soft Tissue and Bone. Lyon: IARC Press. 277-8, 2002
- Yagishita S et al: Secondary osteosarcoma developing 10 years after chemoradiotherapy for non-small-cell lung cancer. Jpn J Clin Oncol. 44(2):191-4, 2014
- Murphey MD et al: The many faces of osteosarcoma. Radiographics. 17(5):1205-31, 1997
