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Segmental Distribution of Calcifications
Wendie A. Berg, MD, PhD, FACR, FSBI
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Linear and branching distribution
          • Definitions

            • Calcification (Ca⁺⁺) in ≥ 1 duct(s) and their branches
            • Involve ≥ 1 segments or lobes of breast

          IMAGING

          • General Features

            • Mammographic Findings

              • Ultrasonographic Findings

                • MR Findings

                  • Image-Guided Biopsy

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Kaltenbach B et al: A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies. Eur J Radiol. 86:221-226, 2017
                                        2. Raj SD et al: Stereotactic biopsy of segmental breast calcifications: Is sampling of anterior and posterior components necessary? Acad Radiol. 23(6):682-6, 2016
                                        3. Kim SY et al: Evaluation of malignancy risk stratification of microcalcifications detected on mammography: a study based on the 5th edition of BI-RADS. Ann Surg Oncol. 22(9):2895-901, 2015
                                        4. Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston: American College of Radiology, 2013
                                        5. Chen PH et al: Segmental breast calcifications. AJR Am J Roentgenol. 199(5):W532-42, 2012
                                        6. Narayanan D et al: Interpretation of positron emission mammography: feature analysis and rates of malignancy. AJR Am J Roentgenol. 196(4):956-70, 2011
                                        7. Bent CK et al: The positive predictive value of BI-RADS microcalcification descriptors and final assessment categories. AJR Am J Roentgenol. 194(5):1378-83, 2010
                                        8. Burnside ES et al: Use of microcalcification descriptors in BI-RADS 4th edition to stratify risk of malignancy. Radiology. 242(2):388-95, 2007
                                        9. Liberman L et al: MRI-guided 9-gauge vacuum-assisted breast biopsy: initial clinical experience. AJR Am J Roentgenol. 185(1):183-93, 2005
                                        10. Morakkabati-Spitz N et al: Diagnostic usefulness of segmental and linear enhancement in dynamic breast MRI. Eur Radiol. 15(9):2010-7, 2005
                                        11. Soo MS et al: Sonographic detection and sonographically guided biopsy of breast microcalcifications. AJR Am J Roentgenol. 180(4):941-8, 2003
                                        12. Liberman L et al: Breast lesions detected on MR imaging: features and positive predictive value. AJR Am J Roentgenol. 179(1):171-8, 2002
                                        13. Liberman L: Percutaneous image-guided core breast biopsy. Radiol Clin North Am. 40(3):483-500, vi, 2002
                                        14. Liberman L et al: Bracketing wires for preoperative breast needle localization. AJR Am J Roentgenol. 177(3):565-72, 2001
                                        15. Liberman L et al: Calcifications highly suggestive of malignancy: comparison of breast biopsy methods. AJR Am J Roentgenol. 177(1):165-72, 2001
                                        16. Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
                                        17. Gluck BS et al: Microcalcifications on postoperative mammograms as an indicator of adequacy of tumor excision. Radiology. 188(2):469-72, 1993
                                        18. Holland R et al: Extent, distribution, and mammographic/histological correlations of breast ductal carcinoma in situ. Lancet. 335(8688):519-22, 1990
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Synonyms

                                                  • Linear and branching distribution
                                                • Definitions

                                                  • Calcification (Ca⁺⁺) in ≥ 1 duct(s) and their branches
                                                  • Involve ≥ 1 segments or lobes of breast

                                                IMAGING

                                                • General Features

                                                  • Mammographic Findings

                                                    • Ultrasonographic Findings

                                                      • MR Findings

                                                        • Image-Guided Biopsy

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Kaltenbach B et al: A matrix of morphology and distribution of calcifications in the breast: Analysis of 849 vacuum-assisted biopsies. Eur J Radiol. 86:221-226, 2017
                                                                              2. Raj SD et al: Stereotactic biopsy of segmental breast calcifications: Is sampling of anterior and posterior components necessary? Acad Radiol. 23(6):682-6, 2016
                                                                              3. Kim SY et al: Evaluation of malignancy risk stratification of microcalcifications detected on mammography: a study based on the 5th edition of BI-RADS. Ann Surg Oncol. 22(9):2895-901, 2015
                                                                              4. Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston: American College of Radiology, 2013
                                                                              5. Chen PH et al: Segmental breast calcifications. AJR Am J Roentgenol. 199(5):W532-42, 2012
                                                                              6. Narayanan D et al: Interpretation of positron emission mammography: feature analysis and rates of malignancy. AJR Am J Roentgenol. 196(4):956-70, 2011
                                                                              7. Bent CK et al: The positive predictive value of BI-RADS microcalcification descriptors and final assessment categories. AJR Am J Roentgenol. 194(5):1378-83, 2010
                                                                              8. Burnside ES et al: Use of microcalcification descriptors in BI-RADS 4th edition to stratify risk of malignancy. Radiology. 242(2):388-95, 2007
                                                                              9. Liberman L et al: MRI-guided 9-gauge vacuum-assisted breast biopsy: initial clinical experience. AJR Am J Roentgenol. 185(1):183-93, 2005
                                                                              10. Morakkabati-Spitz N et al: Diagnostic usefulness of segmental and linear enhancement in dynamic breast MRI. Eur Radiol. 15(9):2010-7, 2005
                                                                              11. Soo MS et al: Sonographic detection and sonographically guided biopsy of breast microcalcifications. AJR Am J Roentgenol. 180(4):941-8, 2003
                                                                              12. Liberman L et al: Breast lesions detected on MR imaging: features and positive predictive value. AJR Am J Roentgenol. 179(1):171-8, 2002
                                                                              13. Liberman L: Percutaneous image-guided core breast biopsy. Radiol Clin North Am. 40(3):483-500, vi, 2002
                                                                              14. Liberman L et al: Bracketing wires for preoperative breast needle localization. AJR Am J Roentgenol. 177(3):565-72, 2001
                                                                              15. Liberman L et al: Calcifications highly suggestive of malignancy: comparison of breast biopsy methods. AJR Am J Roentgenol. 177(1):165-72, 2001
                                                                              16. Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
                                                                              17. Gluck BS et al: Microcalcifications on postoperative mammograms as an indicator of adequacy of tumor excision. Radiology. 188(2):469-72, 1993
                                                                              18. Holland R et al: Extent, distribution, and mammographic/histological correlations of breast ductal carcinoma in situ. Lancet. 335(8688):519-22, 1990